Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
pubmed.ncbi.nlm.nih.gov
Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
1–10 of 65 posts
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#22nd gen antihistamines (Fexofenadine, Cetirizine, Loratidine) are definitely what you want for allergies. 1st gen like Benadryl/Diphenydramine have awful side effects. I highly recommend nasal sprays like Fluticasone as well, available OTC in the US these days and amazing stuff.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#3This is the context I was missing (brand names)
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#4The article is extremely short, but comparing 2-4 OTC doses of diphenhydramine to a level of alcohol concentration above what constitutes a DUI in most places seems like an odd choice? Or is that just a matter of proof of concept, go for the big obvious demonstration first?
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#5This is the context I was missing (brand names) https://www.drugs.com/ingredient/diphenhydramine.html
Yes, it's marketed as ZzzQuil an OTC sleeping aid! (as well as benadryl)
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#650mg diphenhydramine is quite a bit! Anyone who has ever taken that amount for sleep effects will tell you so.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#7The article is extremely short, but comparing 2-4 OTC doses of diphenhydramine to a level of alcohol concentration above what constitutes a DUI in most places seems like an odd choice? Or is that just a matter of proof of concept, go for the big obvious demonstration first?
2 doses of diphenhydramine can have very noticeable and profound effects on many people, 50mg total isn't a light dose by any metric. That seems fine as a comparison to 0.1% BAC.
But 60mg Fexofenadine makes no sense to me in comparison. It's usually 180mg in a single pill.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#82nd gen antihistamines (Fexofenadine, Cetirizine, Loratidine) are definitely what you want for allergies. 1st gen like Benadryl/Diphenydramine have awful side effects. I highly recommend nasal sprays like Fluticasone as well, available OTC in the US these days and amazing stuff.
Fluticasone changed my life. It's a wonder drug.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#9The article is extremely short, but comparing 2-4 OTC doses of diphenhydramine to a level of alcohol concentration above what constitutes a DUI in most places seems like an odd choice? Or is that just a matter of proof of concept, go for the big obvious demonstration first?
The directions I'm looking at for a store brand diphenhydramine say to take 1-2 of the 25mg tablets as needed, so I'd expect that's the typical therapeutic dose.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#102nd gen antihistamines (Fexofenadine, Cetirizine, Loratidine) are definitely what you want for allergies. 1st gen like Benadryl/Diphenydramine have awful side effects. I highly recommend nasal sprays like Fluticasone as well, available OTC in the US these days and amazing stuff.
I would argue that, whatever “generation” it is, cetirizine does not deserve credit for being second generation. I know plenty of people with extremely obvious CNS effects from it. In contrast, loratadine seems innocuous.