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Ask HN: Teach me something new

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341–350 of 782 posts

Re: Ask HN: Teach me something new

#341
post #119

In drug development, a lot of the engineering goes into making sure the pharmaceutical compound -- having been developed -- actually reaches the target area of the body. If the compound is a relatively large particle that needs to get into the blood stream, a nasal spray might result in the compound being deposited at the bottom of a person's lungs without ever getting absorbed. If stomach acids break the chemical do…

that's pharmacokinetics right ?

Re: Ask HN: Teach me something new

#342
I'm gonna throw some Hindu mythology- time travel here.

Did you know that time-travel is a modern concept but in the Indian scriptures, which dates back to thousands of years already mentioned about it. It is a story about King Kakudmi, who sought a husband for his beautiful daughter, Revati. They both had travel to Lord Bhrama's(Creator of the universe) place which was apparently very far from our planet to seek advice. Lord Bhrama then explains them that time moves very differently on his plane of existence and the people they knew on their planet are already dead as it's been 116 million years that has passed in last 20 minutes of Bhrama's time.

They then travel back to Earth after seeking the advice.

Hindu scriptures mentioned a lot of "modern-day concepts" thousands of years back. Isn't it fascinating?

Re: Ask HN: Teach me something new

#343
post #14

Nim ( https://nim-lang.org/ ) is a fast, compiled language that is as easy to use as Python. It doesn't have the same ecosystem or user-base of Python though, although Python and Nim can be bridged via nimpy.

I've been itching to pick up a new language, and Nim is high on the list of choices. But I'm leaning towards Rust, just because it has more recognition and a more evolved ecosystem.

The small ecosystem is Nim's downfall for now, sadly. It really is a much easier language to learn and write in.

I'm working on some Nim modules which will be Open Sourced soon. This will provide a web framework with an ORM. It will be a batteries-included framework.

It will also easily plug-in to a Flutter powered front-end engine which can use Nim defined back-end UI code (not just Nim actually). Also to be Open Sourced soon.

The landing page with a wait-list you can sign-up for: https://nexusdev.tools

Re: Ask HN: Teach me something new

#344
post #232

Ordering a typical printed circuit board with components placed on it is so cheap nowadays that this is a viable option for electeonic hobbyists nowadays (e.g. just ordered 50 pieces of audio output amplifiers at 3,49 € per piece (customs and shipping included), where 1.60 € would be the parts cost of the two chips on it. Only thing you need for this is: 1. An idea and some knowledge about electronics 2. An EDA softw…

Out of all the hobbies I've had, electronics (mostly something to do with the ESP microcontrollers) is the most satisfying one once everything works as intended. While electronics knowledge is hard to learn on your own (in my case), there are tons of communities online that are more than willing to help.

Re: Ask HN: Teach me something new

#345
If you use git and clone the same (or related) repositories in multiple places on a single disk, they can share the hashed object to reduce disk space and/or network usage and increase speed.

One workflow is to git clone mirror the main repo and use that as a shared read-only source of historical references when cloning a new repo. You can also hardlink or reference those objects to save disk space (though some file systems will do that transparently for you).

It feels like this could be done entirely transparently to the user, for a free speed boost but it's not quite there yet and still needs some thought and setup. Some big services use this behind the scenes though so it's presumably robust.

So worth looking into if you are spending time waiting for clones.

Re: Ask HN: Teach me something new

#346

Very few people know the potent facts about the brain: * your neurons are not in your "brain" 90% of your neurons are not in what you generally denote by brain. They are in your cerebellum. The cerebellum has a distinct neural architecture, that difference is in fact clearly visible with the najed eye. A very poor simplistification would be to call it our GPU. * the spinal cord is huge and is structurally a contiguou…

I have a vested interest in very precise understanding of brain structures (qualia too but less pressing matter).

In particular:

- visual perception of self - visual perception of others

and the somatosensory aspect of those points, how do i represent your emotions and body in my head, my own body / image / emotions too; and how do they relate.

if that means anything to anybody, comment down.

Thanks in advance

Re: Ask HN: Teach me something new

#347

Wombat is the only known animal whose poo is cubical. The reason for this appears to be, that this allows the poo to be easily stacked high to mark territory.

The original study of the Bare-nosed wombat was produced by a 15 year old boy, Peter Nicholson, who in the 1960s used to sneak out of his boarding school dormitory of a night to crawl into wombat burrows and make friends with the wombats. He used to "speak wombat" to them and his scientific paper is still cited.

https://www.wombatfoundation.com.au/team-view/peter-nicholso...

https://www.textpublishing.com.au/books/the-secret-life-of-w...

https://www.abc.net.au/austory/the-wombat-boy-march-25,-2002...

Re: Ask HN: Teach me something new

#348

Earlier quoted context omitted.

Ever since I learned that the frequency ratio between adjacent keys on a piano is always a constant twelfth root of 2 regardless of whether you're going black-white or white-white, I've been sort of frustrated with the way pianos are designed. Transposing a song to a different key could have been effortless if keys were structured differently, such as with uniformly alternating white and black keys, rather than the 2…

It is so annoying that standard guitar tuning isn't all perfect fourths and we've decided to throw in a major third between the G-B strings. Bar chords be damned, I want to be able to visualize it symmetrically and have chord shapes that work the same across the fretboard.

You also want open chords. There’s nothing stopping you from tuning the way you describe you’ll find it much harder to play harmony that’s musical if you do though.

Re: Ask HN: Teach me something new

#349

Humans might just be the stupidest animals on the planet when it comes to seasonal migration, we get tied down by our monetary system, taxes, government policies, borders, etc., while polluting our planet with patchwork solutions like air conditioning for the summer or burning fossil fuels to heat our surroundings in the winter. We can't simply just "move" to a different location like other animals.

I think it's the opposite. We can move, but we have the intelligence to tame our environment so we don't have to.

> but we have the intelligence to tame our environment

I beg to differ when most wealthy and well-off Americans get affected by drought, fires, hurricanes, floods, tornadoes, freak snow storms... and still stay in the same place all year round trying to tame their environment.

Re: Ask HN: Teach me something new

#350
post #260

You probably heard about the quirks in the French numerical system. For example, 99 is translated "quatre-vingt-dix-neuf" which is literally "four twenty ten nine". This is a legacy of the base 20 numerical system used by the Celtics thousands of years ago before the modern Romance language drove it out. The hybridization with our current base 10 system came with the Roman conquest of the Gaul. Another example of the…

Surely they the French could figure out that "neuf-dix-neuf" could work as well. I'm learning some South East Asian languages and the simplicity is astounding. Who needs "dix" when "dua dua" works just as well? (Indonesia)
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