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Reversing hearing loss with regenerative therapy

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Re: Reversing hearing loss with regenerative therapy

#91

I really hope this could also help revert tinnitus. This is a life wrecking condition that currently has no cure (suicide attempts 9% for women with severe tinnitus and 5.5% for men).

It’s funny to me seeing everyone in this thread acting like tinnitus is the worst shit ever and they’re suffering everyday. Look up Meniere’s disease. It can be so much worse.

And yes, I understand that suffering is relative and that there are worse things than Meniere’s disease, thank you.

Re: Reversing hearing loss with regenerative therapy

#92
post #61

Earlier quoted context omitted.

I have increasing;y bad tinnitus. Will this help with that? I hear a permanent and constant low-volume very high pitch "squeal" in my ears at all times, I was never a big loud music listener, and I have always brought ear-plugs to loud events - and have had no big ear-rupturing moments (such as a gun firing close to my head without protection etc...

I had odd bouts of tinitus as a teenager, like you, no obvious causes. It went away and came back with a vengence about 15 years ago. That lasted a year or so but over time it's become more of a minor irritation than a major handicap. I guess, my brain has trained itself to deal with it? The only tip I can give you is to always have some kind of background sound that you can focus on rather than the buzzing in your o…

I had pretty severe tinnitus. Getting religious about earplug usage at music performances plus getting musician-specific hearing protection pretty well put it into remission. Cymbals with no earplugs are specifically the worst.

Re: Reversing hearing loss with regenerative therapy

#93
post #4

Disclosure: I own FREQ stock. The failure of the prior trial was suspected, and I believe it, due to a refractory response by overdosing the inner ear with too frequent administrations of the drug, and then testing for effect too soon. I bet even those candidates of the phase IIa trial though would, if checked on now, show some improvement. Animal research has shown that natural cochlear hair cell regeneration and re…

I have increasing;y bad tinnitus. Will this help with that? I hear a permanent and constant low-volume very high pitch "squeal" in my ears at all times, I was never a big loud music listener, and I have always brought ear-plugs to loud events - and have had no big ear-rupturing moments (such as a gun firing close to my head without protection etc...

I have tinnitus too, and would love a cure/solution. I do play drums and have been exposed to loud music, but my tinnitus nevertheless developed from a glandular fever, and my hearing is actually fine. Would just love to get rid of the constant 3-4khz sine waves and enjoy silence again.

Re: Reversing hearing loss with regenerative therapy

#95
post #87

Earlier quoted context omitted.

“Animal research has shown that natural cochlear hair cell regeneration and resultant hearing restoration is very real” - Although exciting, we also need to remember that translatability rates from animal models to humans is notoriously low, usually in the single digits for most therapeutic areas. This is some cool tech, but just wanted to point it out that success in animal models =/= we will eventually get to see t…

> Although exciting, we also need to remember that translatability rates from animal models to humans is notoriously low, usually in the single digits for most therapeutic areas. This is true of humans as well -- there are plenty of programs that get interesting and clear results in Phase 2 (the dose ranging phase: essentially "what dosage is most efficacious") that die in Phase 3 (roughly: "OK, how does that dose re…

     It's also hard to figure out just how the 
     animal's hearing is improving (you can't simply ask)
This seems relatively easy, right? Play a sound at a given frequency, associate it with a food reward. Like Pavlov's dog, but vary the frequency of the bell.

Oversimplification obviously, and "easy" is extreme relative to all the other hard parts involved but that part seems very doable

Re: Reversing hearing loss with regenerative therapy

#96
post #4

Disclosure: I own FREQ stock. The failure of the prior trial was suspected, and I believe it, due to a refractory response by overdosing the inner ear with too frequent administrations of the drug, and then testing for effect too soon. I bet even those candidates of the phase IIa trial though would, if checked on now, show some improvement. Animal research has shown that natural cochlear hair cell regeneration and re…

I have increasing;y bad tinnitus. Will this help with that? I hear a permanent and constant low-volume very high pitch "squeal" in my ears at all times, I was never a big loud music listener, and I have always brought ear-plugs to loud events - and have had no big ear-rupturing moments (such as a gun firing close to my head without protection etc...

My personal albeit anecdotal evidence is that certain foods, or possibly too much sodium, can cause tinnitus. When I have tinnitus I drink a lot of water and reduce my sodium intake - I think that acesulfame postassium (NutraSweet) can cause it for me as well.

You might want to experiment with changing your diet, drinking more water, etc.

Re: Reversing hearing loss with regenerative therapy

#97
post #74

Earlier quoted context omitted.

I have increasing;y bad tinnitus. Will this help with that? I hear a permanent and constant low-volume very high pitch "squeal" in my ears at all times, I was never a big loud music listener, and I have always brought ear-plugs to loud events - and have had no big ear-rupturing moments (such as a gun firing close to my head without protection etc...

There can be other causes besides noise exposure, like TMJ/teeth grinding which can affect the nerves.

For me ibuprofen (at recommend doses, reasons for use etc.) makes it worse/noticeable.

Acetaminophen doesn't have the same problem for me so I'm assuming it's not just that I'm clenching my jaw without noticing.

Re: Reversing hearing loss with regenerative therapy

#98

For anybody suffering with tinnitus I highly recommend the protocol William Shatner went through. You can train your brain so it’s not noticeable any more. Like wearing pants, it fades into the background.

I developed it as a kid, and even though I feel a lot of anxiety in life, I don’t feel anxious about it. Maybe it’s easier for us to accept certain things when we are younger. if it happened today I probably would be more anxious about it. It also helps that mine hasn’t gotten worse - I noticed it, took corrective action, and continue to be mindful about it thru today

[deleted]

Re: Reversing hearing loss with regenerative therapy

#99

Earlier quoted context omitted.

I have increasing;y bad tinnitus. Will this help with that? I hear a permanent and constant low-volume very high pitch "squeal" in my ears at all times, I was never a big loud music listener, and I have always brought ear-plugs to loud events - and have had no big ear-rupturing moments (such as a gun firing close to my head without protection etc...

I vaguely remember hearing something about tapping on the back of your head can greatly reduce tinnitus. I think there are plenty of instructional videos on youtube and it's worth a shot to try.

I've tried this in the past and, for me, it never helped for more than a few minutes. But it DID work. It's amazing how interconnected various systems in our bodies can be and how little we truly understand.

Re: Reversing hearing loss with regenerative therapy

#100

Earlier quoted context omitted.

I have increasing;y bad tinnitus. Will this help with that? I hear a permanent and constant low-volume very high pitch "squeal" in my ears at all times, I was never a big loud music listener, and I have always brought ear-plugs to loud events - and have had no big ear-rupturing moments (such as a gun firing close to my head without protection etc...

I vaguely remember hearing something about tapping on the back of your head can greatly reduce tinnitus. I think there are plenty of instructional videos on youtube and it's worth a shot to try.

It helps some but only for tens of seconds to a minute. Just enough for a tech preview or nostalgia trip (depending on your level of optimism or acceptance), not a solution.
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