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Reversing hearing loss with regenerative therapy

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Re: Reversing hearing loss with regenerative therapy

#41

Post by detritus »

smooc wrote: post #36
detritus wrote: post #25

Earlier quoted context omitted.

I've got pretty bad - although not constant - tinnitus in my left ear after a particularly loud NYE too late in life. What I find interesting though, is that I distinctly remember as a young kid living in the countryside that I found it impossible to hear absolute silence. I distinctly remember sitting on a bale of hay on a bright summer's day with not even a breeze and the quieter I perceived things, the louder a 'T…

O that's interesting. I was able to do the same (tv, refrigerator, etc). I also lived country side and I have hearing loss (35db) and tinnitus (sometimes? moderate?) in my left ear, but seemingly due to a virus infection. I have never encountered someone else that was able to hear whether a tv was on or not. At what distance could you do that?

At least within the house - we moved around a lot, but I lived in a few three storey stonework houses, and could generally tell from 'the other end' of the house if the TV was on.

I don't recall hearing the same noise from fridges though!

Re: Reversing hearing loss with regenerative therapy

#42

Post by magnetic »

Workaccount2 wrote: post #40

I wonder if this will treat hidden hearing loss at all. I check all the boxes for tinnitus behavior (loud blasting music hours a day for years) but only have mild tinnitus at worst. I do however have hidden hearing loss, where I absolutely cannot understand what people are saying if there is too much ambient noise. Bars are hopeless situations for conversation, even a fan on in a room can make conversing difficult. I…

AFAIK hidden hearing loss is due to synaptopathy (see Liberman's work). This work helps regrow hair cells, though. Does your Pure Tone Audiometry show any losses at all on your audiogram? It would be surprising that such an auditory insult had no damaging effect on your hair cells, so you may still benefit from this if it works.

Re: Reversing hearing loss with regenerative therapy

#43

Post by nanidin »

Karawebnetwork wrote: post #34

I really hope this could also help revert tinnitus. This is a life wrecking condition that currently has no cure (suicide attempts 9% for women with severe tinnitus and 5.5% for men).

9% of women with tinnitus attempt suicide, or 9% of women that attempt suicide have tinnitus?

I find it curious since I've had tinnitus since I was very young and it isn't life wrecking - but maybe that's because it is just part of my default life experience.

Re: Reversing hearing loss with regenerative therapy

#44

Post by KennyBlanken »

DantesKite wrote: post #16

For anybody suffering with tinnitus I highly recommend the protocol William Shatner went through. You can train your brain so it’s not noticeable any more. Like wearing pants, it fades into the background.

What is the scientific evidence regarding said "protocol"?

I don't get my medical advice based off what some guy who starred in a low-budget sci-fi space soap for three seasons thinks.

Re: Reversing hearing loss with regenerative therapy

#45

Post by victor106 »

lr4444lr wrote: post #13
taf2 wrote: post #7

Earlier quoted context omitted.

Looks like FREQ stock got really beat down over the last few months- any idea what happened was it the negative outcome of the study you mentioned?

There was suspected fraud on the part of the C(E?)O that he was soliciting investor money (and sold stock himself) with advance knowledge of the disappointing results of the trial I was mentioning and did not disclose it. Class action suits were filed. The trials preceding the Phase IIa results were all extremely promising, and even the Phase IIa one showed statistically significant effect on a sound discrimination ,…

Interesting. Thanks for the honesty.

What other companies are working on this problem?

Re: Reversing hearing loss with regenerative therapy

#46

Post by civilized »

We recently learned that my daughter is completely deaf in one ear. She is a very happy healthy girl otherwise, but it makes me sad to know that currently we have no therapy and she could live her whole life like this. But maybe there will be something for her in a few years.

Re: Reversing hearing loss with regenerative therapy

#47

Post by xivzgrev »

DantesKite wrote: post #16

For anybody suffering with tinnitus I highly recommend the protocol William Shatner went through. You can train your brain so it’s not noticeable any more. Like wearing pants, it fades into the background.

I developed it as a kid, and even though I feel a lot of anxiety in life, I don’t feel anxious about it.

Maybe it’s easier for us to accept certain things when we are younger. if it happened today I probably would be more anxious about it. It also helps that mine hasn’t gotten worse - I noticed it, took corrective action, and continue to be mindful about it thru today

Re: Reversing hearing loss with regenerative therapy

#48

Post by kradeelav »

civilized wrote: post #46

We recently learned that my daughter is completely deaf in one ear. She is a very happy healthy girl otherwise, but it makes me sad to know that currently we have no therapy and she could live her whole life like this. But maybe there will be something for her in a few years.

Hey there - speaking as somebody who was born profoundly deaf but has been hearing 30+ years later thanks to the use of a cochlear implant (CI) and auditory-verbal training, and almost always at the point that people off the street don't realize that I have it ... there's options out there, she doesn't have to live with that constraint. Would highly encourage you to look into the technology there at bare minimum. (The earlier that people have the training/implant, the more exceptional results tend to happen, given there's less delay in speech.)

Happy to share my story and some resources - my email's in the profile. Best of luck to you and your family, and I feel for you.

Re: Reversing hearing loss with regenerative therapy

#49

Post by kradeelav »

I foresee this being wicked cool in combination with current cochlear implant (CI) technology which is already quite mature (30-40+ years). Not a scientist, but something makes me think CI's could at least leap-frog or fill in the gaps of this therapy while it's in a less mature state.

Re: Reversing hearing loss with regenerative therapy

#50

Post by aaaaaaaaaaab »

detritus wrote: post #41
smooc wrote: post #36

Earlier quoted context omitted.

O that's interesting. I was able to do the same (tv, refrigerator, etc). I also lived country side and I have hearing loss (35db) and tinnitus (sometimes? moderate?) in my left ear, but seemingly due to a virus infection. I have never encountered someone else that was able to hear whether a tv was on or not. At what distance could you do that?

At least within the house - we moved around a lot, but I lived in a few three storey stonework houses, and could generally tell from 'the other end' of the house if the TV was on. I don't recall hearing the same noise from fridges though!

It only works with CRT TVs though. It's a 15khz tone, due to magnetostriction in the flyback transformer: https://en.wikipedia.org/wiki/Flyback_transformer
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