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Rare genital defects seen in sons of men taking major diabetes drug

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Re: Rare genital defects seen in sons of men taking major diabetes drug

#211

Post by SpodGaju »

nradov wrote: post #207
SpodGaju wrote: post #199

Earlier quoted context omitted.

What I am saying the medical terminology is the problem. > if the intervention is removed then the condition will return. If the interventions preventing covid are removed the condition will return. Do you get that? On cancer; we all have malignant cells, all the time. everyone right now has cancer cells in their body. https://news.cancerresearchuk.org/2018/04/18/science-surgery... Not smoking is an intervention agai…

I don't understand your point. Most people including me don't engage in daily ongoing interventions to avoid COVID-19. Everyone can expect to get infected with SARS-CoV-2 (probably multiple times) but only a subset of those infections will cause clinically significant COVID-19 symptoms. https://www.medpagetoday.com/opinion/vinay-prasad/94646 Good lifestyle choices can usually prevent type-2 diabetes, but prevention i…

> The zinc deficiency hypothesis is interesting but remains unproven

Just be clear, if the hypothesis was proven it would not be a hypothesis anymore, but would be a theory.

> can't possibly explain large increases in diabetes

You cannot say it is not possible when there is so much evidence that it is possible. Tell me how many people you know diagnosed with diabetes have their doctor get their serum and urinary zinc tested?

https://www.sciencedirect.com/science/article/abs/pii/000293...

"Twenty-five percent of these patients had depressed serum zinc concentrations, and all demonstrated hyperzincurla."

100% had high urinary zinc. 100%. This point to a functional deficiency of zinc. 25% had a true deficiency. It might be that the levels of zinc that we have deemed adequate are not adequate for all people.

and this is a great short peice: https://www.proquest.com/openview/4aaebeab5e4ac98c2d1c3ced49...

The time for research is over, it is time to include serum and urinary zinc testing part of the standard of care for physicians.

And who will pay for this research on a low cost option to reverse diabetes when so much money is to be made on new medications>

> Most people including me don't engage in daily ongoing interventions to avoid COVID-19.

Same could be said for cancer and diabetes. You are probably unknowingly intervening against disease. As far as COVID, you will note the obese are more likely to suffer worse outcomes. So for whatever reason someone watches their weight, even vanity, they are helping prevent themselves from COVID.

> prevention is different from curing an existing condition

My mother prevented her self from having the symptoms of having the symptoms of diabetes occur again by changing her diet. How is that different from curing it?

Listen, what is a disease but a collection of symptoms? If I have no symptoms, where is the disease? If I had diabetes, but was never diagnosed, and I treated myself with a diet to make it go away, would a doctor diagnose diabetes when my blood sugar was normal? Funny, it sounds like you are saying doctors causes permanent diseases?

Re: Rare genital defects seen in sons of men taking major diabetes drug

#212

Post by giantg2 »

kadoban wrote: post #174
giantg2 wrote: post #153

Earlier quoted context omitted.

Considering the root(?) commenter said that a low carb diet did in fact work for them even though they had to go research it on their own, it sounds like it was effective.

A lot of diets work at least in the short/medium term, for those that have selection bias and "completed" them. That's very much _not_ the same thing as a doctor recommending or prescribing them having any effect.

There's no talk of completion. This isn't a "diet", it's a diet. We aren't using it as some colloquial meaning for losing weight, etc. This is about a lifelong dietary change to address excessive carbohydrate intake.

If it doesn't have "any effect" then I guess all type 1 diabetics are already dead?

The point still stands - doctors should be counseling diabetics on dietary changes, even if they are being prescribed medication. Some patients can improve their condition and overall health to the point that they can stop the medication. If you disagree with this, please, show me some sources. As for mine, you can check the AMA, AHA, ADA, and PubMed (American Medical/Heart/Diabetes Associations).

Re: Rare genital defects seen in sons of men taking major diabetes drug

#213

Post by collegeburner »

Lammy wrote: post #76
mensetmanusman wrote: post #28

It’s sad seeing the crazy downstream multigenerational damage that massive sugar consumption is causing as obesity rates reach 50%. Good luck future humanity.

Our leaders have been calling for a population decrease since around the time of the civil rights era, so maybe future-humanity gets a coincidental-but-desired outcome after all? https://files.eric.ed.gov/fulltext/ED050960.pdf#page=10 "The time has come to ask what level of population growth is good for the United States. There was a period when rapid growth made better sense ks we sought to settle a continent and bu…

If we're going to decrease population then we should probably start finding ways to encourage reproducing only among the most genetically fit. There's a fine line to be walked with this line kind of thinking and itspast, but if we're going to so limit the pool of available physical and intellectual talent, we should make sure we minimize handicaps, obesity, addiction, mental illness, etc.

Hopefully, gene editing obviates the these concerns.

Re: Rare genital defects seen in sons of men taking major diabetes drug

#214

Post by collegeburner »

adewinter wrote: post #60
ecf wrote: post #38

Earlier quoted context omitted.

It’s an extremely sad situation and will guarantee every single healthcare system eventually breaks down.

You're saying that it's a guarantee that every single healthcare system (in the world?) will break down because of _sugar consumption_? Seriously?

Almost every health care system is based on shared payment. Either insurance or socialized medicine, it's similar with a varying amount of pooling. If almost everybody is obese, us few healthy people may end up stuck paying for the fatties. And eventually, there will be too many fatties, they will vote that they can't be pooled separately so we have to pay even more, and there will at some point be too few of us.

IInsurance for me should be very low. I am in great shape by anybody's measure. But all the drunks, junkies, fatties, make my payments so high I've debated dropping medical insurance.

Re: Rare genital defects seen in sons of men taking major diabetes drug

#215

Post by watwut »

nradov wrote: post #200
watwut wrote: post #169

Earlier quoted context omitted.

> Doctors are now seeing children come in fatty liver disease. That never used to happen. They used to die of malnutrition of all kinds. Not just because of being poor, but because of us not knowing this or that is necessary in food. The physical work people used to do was body breaking fairly often. The chemicals people used to be in daily contact with were body damaging too.

Well now you're just making things up. Deaths from nutritional deficiency have always been extremely rare in the USA. Outside of some isolated cases of abuse or neglect or mental illness, only the poorest people ever died of malnutrition. It has never been among the leading causes of death. Knowing this or that is necessary in food is mostly just of academic interest and hasn't actually produced better health outcome…

This is not true. The malnutrition of some kind is not rare and diseases from it were life. Malnutrition is not famine. It is lack of Iron and anemia. It is Rickets due to lacking calcium. It is missing any of vitamins - like being sickly in winter due to lack of vitamin C.

It is missing Iodine which is now commonly added to salt.

You can be overfed in calories and still suffer from malnutrition. Especially without science we have now. And whole classes of sicknesses caused by malnutrition don't exist anymore.

Re: Rare genital defects seen in sons of men taking major diabetes drug

#216

Post by AmericanChopper »

bladley wrote: post #209
AmericanChopper wrote: post #138

Earlier quoted context omitted.

No food is specifically obesity inducing, and you personally are responsible for everything you choose to eat, not a politician.

> No food is specifically obesity inducing This is false. Of course certain foods are metabolized in ways that are more likely to lead to obesity than others.

Absolute nonsense. Your food contains calories in the form of carbohydrates, protein and fat. None of those macronutrients are metabolized in a way that is likely to lead to obesity. Obesity comes from consuming more calories than you burn. It doesn’t matter at all where those calories come from.

Re: Rare genital defects seen in sons of men taking major diabetes drug

#217

Post by zaroth »

ch0I9daAiO wrote: post #149
robbiep wrote: post #48

Earlier quoted context omitted.

In responding to your example first - to start with, I live and practice in a country where it isn't a choice between healthcare and food on the table. Beyond that, I believe that it is a basic human right to have free healthcare. The next bit is a bit more complex. I don't think it is right or sensible to advertise medications to people directly. The US is almost alone amongst industrialised/western countries in hav…

For finasteride I agree, as it decreases DHT, which is not exactly a useless hormone. It shouldn't be prescribed to anyone, as you have said. I don't necessarily agree for the Viagra/Cialis. Generally cialis is safer than viagra, with less side effects. But their mechanism of action is quite simple and doesn't cascade to a lot of other body functions, inhibition of PDE5. Viagra also inhibits PDE6 more, thats why you…

> If you can get an erection in the morning, while you're sleeping, PDE5 inhibitors won't help.

Did you mean to say can’t?

Re: Rare genital defects seen in sons of men taking major diabetes drug

#218

Post by Lammy »

ovi256 wrote: post #114
Lammy wrote: post #76

Earlier quoted context omitted.

Our leaders have been calling for a population decrease since around the time of the civil rights era, so maybe future-humanity gets a coincidental-but-desired outcome after all? https://files.eric.ed.gov/fulltext/ED050960.pdf#page=10 "The time has come to ask what level of population growth is good for the United States. There was a period when rapid growth made better sense ks we sought to settle a continent and bu…

Fringe leaders call for fringe positions all the time. None of the authors of that paper were elected officials, and that view never became policy of any state.

> and that view never became policy of any state.

Not officially anyway: https://wtfhappenedin1971.com/

Re: Rare genital defects seen in sons of men taking major diabetes drug

#219

Post by robbiep »

ch0I9daAiO wrote: post #149
robbiep wrote: post #48

Earlier quoted context omitted.

In responding to your example first - to start with, I live and practice in a country where it isn't a choice between healthcare and food on the table. Beyond that, I believe that it is a basic human right to have free healthcare. The next bit is a bit more complex. I don't think it is right or sensible to advertise medications to people directly. The US is almost alone amongst industrialised/western countries in hav…

For finasteride I agree, as it decreases DHT, which is not exactly a useless hormone. It shouldn't be prescribed to anyone, as you have said. I don't necessarily agree for the Viagra/Cialis. Generally cialis is safer than viagra, with less side effects. But their mechanism of action is quite simple and doesn't cascade to a lot of other body functions, inhibition of PDE5. Viagra also inhibits PDE6 more, thats why you…

I agree that viagra/cialis are generally safe for the majority of people. I guess the question with regard to the subscription prescription model is what are the subset of medications that fall into the right risk profile for the model to work effectively? It's a pretty small subset without adequate safeguards!

Re: Rare genital defects seen in sons of men taking major diabetes drug

#220

Post by fleddr »

chillingeffect wrote: post #161
fleddr wrote: post #134

Earlier quoted context omitted.

It's much more harmful to obsess over the optics of something potentially offensive at the expense of reality. None of the excuses you listed hold any ground. Time: it costs about 20 minutes to cook a simple, basic fresh meal. With a single weekly groceries delivery (or visit to the store), you're covered for some 5-6 main meals as well as breakfast and lunch. Are you telling me Americans don't have 20 minutes to pre…

Youve identified the chain but keep it going: stress and lack of sleep! Ubiquitous coffee, economic pressure, overpriced and weak preventative healthcare system, social pressure, status anxiety, housing insecurity, political threats, public-facing crimes, rampant racism. These all test our self-control around food.

None of those things help, yet none of those things prevent healthy living. For the simple reason that healthy living does not cost a lot of time or money.

Like I said, home cook 5-6 days per week, which costs little time or money. None of the issues you mention prevent you from doing it. Exercise costs no money at all.

I don't mean to dismiss your reasons as if they don't matter at all, I'm stating they are a trap. They provide a shield to hide behind. If only all of that would improve, I'd be healthier. This imaginary utopian society will not make you healthier. You become healthier by stop eating crap.

Nobody's going to do that for you, but you.

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