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Man given genetically modified pig heart dies

bbc.com

191–200 of 241 posts

Re: Man given genetically modified pig heart dies

#192
post #189

Earlier quoted context omitted.

It's hardly penance to be given the chance to live longer.

You seem to be missing the point - his repayment to society was being the guinea pig for a medical experiment, which would have been unethical to do on somebody in nearly any other circumstance.

Another comment points out that his crime was not taken into account, only the fact that he had no other medical procedures as options due to his ill health and history of not following doctor's orders.

So what's the point I missed?

Re: Man given genetically modified pig heart dies

#194

Earlier quoted context omitted.

Funny how having had COVID opens doors (eg. quarantine not required when traveling to some countries, and your example), but at the same time people are punished for not preventing it (vaccination, PPE). Talk about mixed incentives...

> (eg. quarantine not required when traveling to some countries, and your example) For policies like quarantine following travel does it make any sense to distinguish anyone whether they have had covid, had a vaccine, had both a vaccine and covid, or had neither a vaccine or covid? Aren’t all of the above equally capable of carrying and transmitting the virus?

I thought the last one on the list (neither vaccine nor covid) has a higher chance of carrying covid.

Re: Man given genetically modified pig heart dies

#195
post #104

Earlier quoted context omitted.

I’m glad this team was more concerned about science and minimizing risk than PR. Hopefully negative press doesn’t cause much of a hinderance.

How is this negative press? This transplant was a huge success.

It is bad press for people who only read (or understand) headlines.

The man with the pig heart died. Sounds bad. Pig heart not good.

Swipe.

Next newsflash.

Re: Man given genetically modified pig heart dies

#196
post #84

Earlier quoted context omitted.

Well that really raises the question of what did he die from? If not from the heart, how do they proceed with the research? Gotta do the next one on a person whose not already nearly gone. That seems like a highly sensitive line, no doubt it's a big discussion to move it.

"What people die of" seems like the sort of question the medical community should be quite good at answering. People are waiting for human heart transplants and dying from the wait. I don't think there will be a shortage of patients who we can ethically treat whilst researching this new technique. It certainly isn't binary with a hard "sensitive line".

> "What people die of" seems like the sort of question the medical community should be quite good at answering.

Does it? As far as I know, not only are they happy to admit that they can't do it, efforts to try have mostly ceased. We used to do autopsies.

https://www.todaysgeriatricmedicine.com/archive/SO17p26.shtm...

> In the United States it is estimated that the rate of major errors (eg, incorrect cause of death [CoD], incorrect manner of death) found on death certificates completed at academic institutions is approximately 33% to 40%. Internationally, this rate at some hospitals rises as high as 80%

> A wealth of literature is available highlighting the prevalence of death certificate inaccuracy seen at the national and international levels, as well as multiple studies that indicate lack of training as the root cause in the United States. Despite these noted errors, death certificate data continue to inform research pathways and drive medical practice.

https://americanmind.org/salvo/a-covid-death-the-bureaucracy...

> natural cause of death reports are known to have a 20 percent to 60 percent inaccuracy rate according to the peer-reviewed literature.

> The system isn’t built to allow for investigation. In fact, in the state where I worked, doctors are supposed to provide causes of death within 15 hours of the death

> 30 percent of doctors have reported being instructed by the coroner to put an inaccurate cause of death on purpose so the [coroner's] office won’t need to take the case.

> When I worked as a death certificate clerk, I occasionally would send death certificate worksheets to multiple doctors involved in a patient’s care if we had a rush to bury or cremate. In these situations we needed to cast a wider net to find a rapidly responding doctor to finish the record before final disposition. Many times each physician would report an entirely different cause of death.

Death certificates and cause-of-death attribution mainly exist to satisfy procedural requirements, not because they're supposed to be informative or helpful. Courts need to do cause-of-death attribution. It can't be done. So they solve their problem by the very simple method of pretending they can do it anyway. (Courts take this approach everywhere, not just in death certificates. Drug dogs, accounting errors, expert testimony...)

Re: Man given genetically modified pig heart dies

#197
post #22

Earlier quoted context omitted.

In the US I presume? Canadians have a harder time... In Canada/Ontario, you have to convince your doctor to give you a cholesterol test, e.g. family history. It won't be done preventively [1]. Even if you manage to get tested, if you're under 40 the doctor won't care and there will be no followup. [1] https://exechealth.ca/ontario-drops-annual-physicals/

A test in the US < $50 and is easy to schedule without having a doctor involved at LabCore or similar. Is that an option in CA?

That's interesting pricing. I just did some blood tests at Quest Labs w/o a Dr and it ran me $200

Re: Man given genetically modified pig heart dies

#198

Earlier quoted context omitted.

To be honest, not sure why we spend so much resources on heart transplants. For the most part, the underlying condition that wrecked your old heart is probably still there. We should be putting more resources into preventative medicine.

Preventative medicine is well understood and widely available. People just aren't interested or unresponsive to treatment.

This. I know a doctor who was heading the liver transplant list. Patients would come in, be diagnosed and told they need to live healthier, do this and do that as part of the preventative measures. Clear medical advice. Habitual change is the hardest in my view and this is also how this story continues. Over the course of time these patients will visit regularly. Their condition is worsening and the preventative medical advice will be stronger and more urgent. In the end most still end in the transplant list. Most having exhibited little effort to turn their life around.

Re: Man given genetically modified pig heart dies

#199
post #90

Earlier quoted context omitted.

Isn't that something that you could sue for?

Is it just me or is this such a stereotypical American comment?

I’m not american and thought this would be a good generic word to convey “getting some answers/justice”.

I’ve had so many infuriating encounters with dismissive doctors, that I fear I’ll get into a similar situation.

The healthcare system is really strained, but does it have to give them the right to not take your “only annoying, not life threatening” level of simptoms seriously?

I do not have the resources to go for three different doctors to really make sure they are right about telling me “just don’t worry about it..”

Re: Man given genetically modified pig heart dies

#200

Earlier quoted context omitted.

I thought that hospitals specifically only put you on the list if you committed to a healthy lifestyle.

It likely varies hospital to hospital and region to region. I would hope it's more often the case than not though. I'm an organ donor and I wouldn't be happy to find out that my liver went to an alcoholic that wasn't making a strong effort at sobriety.

Do you know how arrogant that is? Alcoholics aren't people who deserve to die because of some kind of moral failing. Very often they're alcoholic because of other mental health problems or abuse. Would you want to deny a clininically depressed person your liver because they might commit suicide?
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