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Four-year-old Israeli child tests positive for polio, first case since 1989

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Re: Four-year-old Israeli child tests positive for polio, first case since 1989

#4
> Indications of the virus have been found in sewage samples in the area

Oh this decade is going to be insane. We have the technology to solve so much but people no longer have the education and thinking process to use it. Disease and war back on the front burners.

Re: Four-year-old Israeli child tests positive for polio, first case since 1989

#5
You might wonder how polio gets reintroduced into Israel or anywhere else. The polio vaccines we currently use are imperfect.

The oral vaccine is a weakened form but it mutates in the neighborhood of one in a million cases to become effectively wild polio and some years this accounts for most of the poliomyelitis cases.

On the other hand, the fully inactivated injected vaccine is non-sterilizing: it prevents poliomyelitis but still allows for gut infection. This eradicates the disease but not the virus. This is why they previously found the polio virus in sewage samples even though there were no poliomyelitis cases.

Most anger at the un-vaccinated (due to the assumption that they are causing the spread) seems mis-placed since those vaccinated by the injected form (that's probably you commenting on Hacker News!) will spread the polio virus as well.

Re: Four-year-old Israeli child tests positive for polio, first case since 1989

#8
post #5

You might wonder how polio gets reintroduced into Israel or anywhere else. The polio vaccines we currently use are imperfect. The oral vaccine is a weakened form but it mutates in the neighborhood of one in a million cases to become effectively wild polio and some years this accounts for most of the poliomyelitis cases. On the other hand, the fully inactivated injected vaccine is non-sterilizing: it prevents poliomye…

This is also somewhat complicated because, as the article notes, sewage monitoring in Israel picks up polio virus with some degree of frequency, despite there being no recorded cases - there's definitely shedding going on, and it's sort of an odd case due to a number of demographic and geopolitical factors.

This is not necessarily something that can be attributed to the vaccine. Will be curious to see what the results are if they try to trace it back.

Re: Four-year-old Israeli child tests positive for polio, first case since 1989

#9
post #5

You might wonder how polio gets reintroduced into Israel or anywhere else. The polio vaccines we currently use are imperfect. The oral vaccine is a weakened form but it mutates in the neighborhood of one in a million cases to become effectively wild polio and some years this accounts for most of the poliomyelitis cases. On the other hand, the fully inactivated injected vaccine is non-sterilizing: it prevents poliomye…

This bears some correction. As the article reports, the strain that caused infection was traced from Malawi/Pakistan, where there is still endemic polio because of long-lasting vaccine hesitancy.

Re: Four-year-old Israeli child tests positive for polio, first case since 1989

#10
post #5

You might wonder how polio gets reintroduced into Israel or anywhere else. The polio vaccines we currently use are imperfect. The oral vaccine is a weakened form but it mutates in the neighborhood of one in a million cases to become effectively wild polio and some years this accounts for most of the poliomyelitis cases. On the other hand, the fully inactivated injected vaccine is non-sterilizing: it prevents poliomye…

> Most anger at the un-vaccinated (due to the assumption that they are causing the spread) seems mis-placed since those vaccinated by the injected form (that's probably you commenting on Hacker News!) will spread the polio virus as well.

Seriously. In what population does polio spread, the unnvacinnated or the vaccinated? In what population are you exposed to it?

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