Promising HIV vaccine passes phase one human trials with 90% success rate
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Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#2"if this genetic cocktail passes Phase II and Phase III future clinic trials, and makes it into production, in the future HIV could be compared to herpes virus nowadays".
As far as I know there is no herpes vaccine and herpes stays with you for life resulting in recurring problems. Doesn't quite sound like a very flattering comparison to an effective vaccine solution.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#3"if this genetic cocktail passes Phase II and Phase III future clinic trials, and makes it into production, in the future HIV could be compared to herpes virus nowadays". As far as I know there is no herpes vaccine and herpes stays with you for life resulting in recurring problems. Doesn't quite sound like a very flattering comparison to an effective vaccine solution.
Chickenpox is a form of herpes and we all have it. What matters is that it's harmless.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#4"if this genetic cocktail passes Phase II and Phase III future clinic trials, and makes it into production, in the future HIV could be compared to herpes virus nowadays". As far as I know there is no herpes vaccine and herpes stays with you for life resulting in recurring problems. Doesn't quite sound like a very flattering comparison to an effective vaccine solution.
Pretty sure they're talking about the still annoying but no death part.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#5"if this genetic cocktail passes Phase II and Phase III future clinic trials, and makes it into production, in the future HIV could be compared to herpes virus nowadays". As far as I know there is no herpes vaccine and herpes stays with you for life resulting in recurring problems. Doesn't quite sound like a very flattering comparison to an effective vaccine solution.
Chickenpox is a form of herpes and we all have it. What matters is that it's harmless.
While it won't probably kill you, it isn't exactly harmless. It can reemerge as shingles.
There are cases of herpes causing death. For example, in an infant infected by his mohel, and a laboratory researcher killed after exposure to monkey feces. (http://www.cdc.gov/mmwr/preview/mmwrhtml/00056008.htm)
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#6Earlier quoted context omitted.
Chickenpox is a form of herpes and we all have it. What matters is that it's harmless.
While it won't probably kill you, it isn't exactly harmless. It can reemerge as shingles. There are cases of herpes causing death. For example, in an infant infected by his mohel, and a laboratory researcher killed after exposure to monkey feces. ( http://www.cdc.gov/mmwr/preview/mmwrhtml/00056008.htm )
Yes, but those cases are much, much less worrisome than AIDs in its current state.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#7"if this genetic cocktail passes Phase II and Phase III future clinic trials, and makes it into production, in the future HIV could be compared to herpes virus nowadays". As far as I know there is no herpes vaccine and herpes stays with you for life resulting in recurring problems. Doesn't quite sound like a very flattering comparison to an effective vaccine solution.
Chickenpox is a form of herpes and we all have it. What matters is that it's harmless.
Varicella pneumonia? Encephalitis? The virus that causes chicken pox is not harmless.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#8Easy to miss: "The recent human trials involved 30 healthy volunteers, where 24 were treated with MVA-B, while the other 6 were treated with a placebo, carried out over a 48 week period."
This test was done on healthy volunteers, not ones with HIV. Although it's promising that 90% of the patients showed an immune response, we don't know how well that immune response translates into therapeutic benefit until it's trialled on HIV-positive patients.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#9Earlier quoted context omitted.
Chickenpox is a form of herpes and we all have it. What matters is that it's harmless.
While it won't probably kill you, it isn't exactly harmless. It can reemerge as shingles. There are cases of herpes causing death. For example, in an infant infected by his mohel, and a laboratory researcher killed after exposure to monkey feces. ( http://www.cdc.gov/mmwr/preview/mmwrhtml/00056008.htm )
Shingles can be very nasty - my mother had it after I had chickenpox. It was across her face and eyes - she was hospitalised and was on morphine for the pain.
Re: Promising HIV vaccine passes phase one human trials with 90% success rate
#10Easy to miss: "The recent human trials involved 30 healthy volunteers, where 24 were treated with MVA-B, while the other 6 were treated with a placebo, carried out over a 48 week period." This test was done on healthy volunteers, not ones with HIV. Although it's promising that 90% of the patients showed an immune response, we don't know how well that immune response translates into therapeutic benefit until it's tria…
Isn't the point of a vaccine to prevent, not cure?
EDIT: thanks guys, but I have enough upvotes. My comment didn't add much to HN. Wasn't actually trying to prove him wrong -- I thought I'd missed something and was asking for clarification.