Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
universityofcalifornia.edu
Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
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Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#2No post body was provided.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#3It's worth pointing out that the "genetic changes" in question are changes in gene expression.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#4> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance.
> “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,”
Italics mine.
Linoleic acid is what induces torpor (hibernation) in mammals. We are mammals. People in the modern world are possibly something like half hibernating, inclusive of mental effects and of course the effect on difficult-to-remove-weight. The rise in Soybean oil consumption is an enormous change in the human diet over the last 50 years. The scale of it replacing so many fats, especially formerly animal fats, is just huge.
See: Humans and Hibernating Mammals React to The Same Amount of Dietary Linoleic Acid in the Same Way. By Becoming Torpid.
https://fireinabottle.net/humans-and-hibernating-mammals-rea...
(I submitted that article because I think its worth its own discussion: https://news.ycombinator.com/item?id=30456454)
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#5It's worth pointing out that the "genetic changes" in question are changes in gene expression .
Could you elaborate on that? It doesn't surprise we that "genetic changes" is used sensationally, just would like to know what is actually happening and whether it's uncommon or something pretty normal?
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#6Soybean oil the most widely consumed? I would never have guessed. Figured canola would be.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#7It's worth pointing out that the "genetic changes" in question are changes in gene expression .
Could you elaborate on that? It doesn't surprise we that "genetic changes" is used sensationally, just would like to know what is actually happening and whether it's uncommon or something pretty normal?
In the simplest terms:
Gene expression constantly changes. It's a field known as epigenetics.
You have tons of genes, not all of which are constantly active.
You have histones in your DNA that allow certain portions to be read while others are locked away. This changes how your genes activate.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#8What is soybean oil traditionally called in the US? I've never actually seen "soybean oil" myself (though it surely exists). Is this the same as "vegetable oil"?
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#9In mice. Let's temper the usual nutritional conspiracy allegations and grand proclamations of effects on humans until someone trained and knowledgable provides an interpretation of this study. Most of these rodent studies end up not being applicable to humans anyway.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#10Recommended viewing: Dr. Chris Knobbe - Diseases of Civilization: Are Seed Oil Excesses the Unifying Mechanism?
https://www.youtube.com/watch?v=7kGnfXXIKZM
Here's a slide where he shows that soybean oil induces diabetes (in mice):
https://youtu.be/7kGnfXXIKZM?t=2341
The talk makes the case on how it's also applicable to humans.