See Vanity Fair's excellent long-form article "The Body in Room 348" for a real life example! https://www.vanityfair.com/culture/2013/05/true-crime-elegan...
Without reading mode, that site is unusable. All those animated ads and banners are the blink tag all over again.
You answered yourself. Read View is great even with well-behaved sites, use it generously.
Edit: I retract my comment, Reader View shows about the last third of the article, and I had already blocked JavaScript there in a previous interaction. Vanity Fair sucks.