I'll probably be a minority here, but I'd say: java + Vaadin [1] + raw jdbc (no ORM nonsense). On Vaadin site, you can use starter [2] to create an app template. There is no need to write javascript; most Vaadin code looks like good old desktop programming. Due Java stability, that thing will run forever and will be performant. If you want to be "cloud native" (or whatever cool name now is) in the future, you can lat…
Backend: Java, C#, F#
Frontend: Svelte, React
Deployment: AWS with Pulumi
This yields to a pretty good TCO.