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Gut microbe linked to depression in large health study

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Re: Gut microbe linked to depression in large health study

#171
post #114

Earlier quoted context omitted.

Also why would GMO be bad? The criticism comes mostly from people that also believe in osteopathic / homeopathic medicine in my social circle. I find it a terrific chance for humanity to engineer plants in such a way that they are more robust against disease and bad weather (with CRISPR/CAS and such methods).

Anti - GMO crowd is definetly very similar to anti vaxxers and other science deniers spreading dangerous propaganda while eating oranges and bananas.

Nature produces both edible products, inedible products, and toxic or partially edible (tomatoes, potatoes, etc.) products. AFAIK, there is almost no risk in transferring genes from one edible non-toxic product to another edible non-toxic product. For all other gene transfers, testing is required.

Re: Gut microbe linked to depression in large health study

#172
post #171

Earlier quoted context omitted.

Anti - GMO crowd is definetly very similar to anti vaxxers and other science deniers spreading dangerous propaganda while eating oranges and bananas.

Nature produces both edible products, inedible products, and toxic or partially edible (tomatoes, potatoes, etc.) products. AFAIK, there is almost no risk in transferring genes from one edible non-toxic product to another edible non-toxic product. For all other gene transfers, testing is required.

"AFAIK, there is almost no risk in transferring genes from one edible non-toxic product to another edible non-toxic product. "

And where is your knowledge coming from?

I am certainly not a biologist, but as far as I know, there are quite some plants that are edible in the breed we eat - but a different wild form is toxic (carrots for example). How are you sure, the wrong (dormant) genes do not get transfered and activated, without testing?

Or even with the same plant, potatoes. The root is good for us, but the flower is toxic.

In other words, you always have to do extensive testing, when you play around with genes.

Genes are not computer modules you just swap around and turn on and off. It is way more complicated.

Re: Gut microbe linked to depression in large health study

#174
post #140

Earlier quoted context omitted.

Anti - GMO crowd is definetly very similar to anti vaxxers and other science deniers spreading dangerous propaganda while eating oranges and bananas.

Don't forget the 5G radiation...

I bet you two are the type who smugly told everyone off for believing the "completely disproven" lab leak theory for a year, before never mentioning it again.

Re: Gut microbe linked to depression in large health study

#175

Earlier quoted context omitted.

At the current pace of research and studies, when do you think we could expect to see something come to 'market' that could be used - first as a diagnosis and then as a treatment/medication/technique. As someone with IBS - right now I feel like there is no clear 'problem' defined for it. You are just categorized by the doctor (Rome 3 or whatever) and people go through various tests, medications, non-fda approved stuf…

Also have an IBS diagnosis. Had a great doctor that helped me get started, after many that did a shoddy job, and this has been my experience as well. Very much a 'seems like IBS, try low FODMAP, see what works and doesn't via experience,' which was pretty amazing/alarming how little is understood about our guts. I'd love to know when the science is going to start catching up. Especially since I think it'll be interes…

I'm wondering if someone can help, re low FODMAP diet, as I'm finding some contradictory information about which foods are low FODMAP.

For example, at [1], Chickpeas are listed as low FODMAP, but at [2] they're listed as "high". Similarly for Green bell peppers.

Thanks for any help.

[1] https://www.ibsdiets.org/wp-content/uploads/2016/03/IBSDiets... [2] https://med.virginia.edu/ginutrition/wp-content/uploads/site...

Re: Gut microbe linked to depression in large health study

#176
post #158

Just another data point, but my journey through digestive issues and recovery was kicked off by the worst depression and burnout I ever experienced, which started in 2019 and lasted 3 years. My best guess for what happened is that work stress, excessive celebration and coping with the cognitive dissonance of the pre-COVID era and subsequent pandemic, combined with overtraining and the misuse of protein shakes in plac…

So, what are you actually eating now that has helped?

He mentioned that he's avoiding lectins. For that, checkout the book "The Plant Paradox".

The food list is here:

https://gundrymd.com/dr-gundry-diet-food-list/

Re: Gut microbe linked to depression in large health study

#177
post #159
post #124

There was a lot of work on microbiome and cancer immunotherapy... the latest study in the field published in the most prestigious journal there is [1] seemed to show that fibre intake was more important than any specific microbe. In fact they found that eating more fibre and taking probiotics resulted in worse outcomes than just eating more fibre alone. This was recapitulated in a mouse model: > Together, these data…

Why only more vegetables? Isn’t fiber also in some other food?

The amount of fibre in vegetables is enormous compared to most other foods, especially including “high in fibre” manufactured foods.

Re: Gut microbe linked to depression in large health study

#178
post #159
post #124

There was a lot of work on microbiome and cancer immunotherapy... the latest study in the field published in the most prestigious journal there is [1] seemed to show that fibre intake was more important than any specific microbe. In fact they found that eating more fibre and taking probiotics resulted in worse outcomes than just eating more fibre alone. This was recapitulated in a mouse model: > Together, these data…

Why only more vegetables? Isn’t fiber also in some other food?

Fiber being a type of carb is also found in other high carb foods like beans, whole grains, potatoes (with skin), and popcorn. Beans are the best source of fiber by a mile in terms of quantity.

Re: Gut microbe linked to depression in large health study

#179
post #121
post #29

Gut microbiome researcher here - not involved in this study but happy to answer questions or dig in with anyone interested!

What supplements do you take based on your scientific background?

I don't have much knowledge on supplements or even diet - beyond it's intersection with the microbiome. From the microbial perspective I think traditional dietary stuff is enough - eat fibrous plants and legumes and that's all you need to do.

Re: Gut microbe linked to depression in large health study

#180
post #124

There was a lot of work on microbiome and cancer immunotherapy... the latest study in the field published in the most prestigious journal there is [1] seemed to show that fibre intake was more important than any specific microbe. In fact they found that eating more fibre and taking probiotics resulted in worse outcomes than just eating more fibre alone. This was recapitulated in a mouse model: > Together, these data…

Are insoluble and soluble fiber equivalent in this respect?

My gut (pardon the pun) says insoluble is more important, but I'm not sure if that's true.

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