Is there a miniature ASIO soundcard planned for one of the slots? Not needing to carry an external audio interface around when working within a DAW is a major factor that's keeping me on MacOS (both pro audio and consumer use the same driver there).
They publish the CAD files (both mechanical and electrical) on GitHub with instructions on how to manufacture your own expansion cards. I believe the interface within the expansion cards is just standard USB-C. If someone could manage to squeeze all the necessary components within the physical dimensions, it should be possible to make your own soundcard expansion card. https://github.com/FrameworkComputer/ExpansionCa…
I don't know how much licensing would cost, but Framework could possibly offer a driver for the internal card as an addon. Then the slot could be used for a small headphone amp which would be more third party friendly I think.