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Quebec bans unvaccinated from buying groceries at Walmart, Costco

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Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#2
The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa are not protected by serum igG antibodies. And the T cells trained by intramuscular vaccination are not tissue resident in the upper respiratory where they are needed to stop infection. They just do a pretty darn good job at preventing serious disease.

I wish governments of the world would heavily invest in the current and future intranasal sars-cov-2 boosters to prevent spread and follow up on the strong base of intramuscular body protection. I might not even be opposed to mandating intranasal vaccinations since they would stop spread. But this? This doesn't make a lot of scientific sense.

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#3
post #2

The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa ar…

I’ll take a shot in the arm, but my nose? Eehhhh…

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#5
post #2

The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa ar…

The Quebec government's major concern is protecting their health care system. The Canadian health care system was quite stretched pre-pandemic, and it wouldn't take much to break it.

The goal at this point is less about preventing the spread than it is about increasing the vaccination rate to keep people out of hospitals.

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#6
post #2

The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa ar…

Quebec has a heavily socialized medical system.

10% of the population is unvaccinated, but make up >50% of COVID beds in hopitals, a significant fraction of the *entire medical system*.

At some point the other 90% of taxpayers shouldn't subsidized the stupid decisions of the remaining 10%.

I'm not saying banning grocery store access is necessarily it, but something needs to be done

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#7
post #3
post #2

The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa ar…

I’ll take a shot in the arm, but my nose? Eehhhh…

It happened with Polio.

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#8
post #2

The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa ar…

> This doesn't make a lot of scientific sense.

This policy is the most flagrant targeted political attack. It has nothing to do with science. If you start restricting people’s ability to feed and clothe themselves you’ve crossed a very dark line.

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#9
post #4

The UK, Denmark and others moving to get rid of ALL restrictions. Meanwhile Canada, Australia and others devolving into police states... Edit - forgot some other countries. Netherlands, Ireland also ditching restrictions...

The UK is only doing that because the PM has been so fragile because he's screwed up covid related things for so long he needs the backbenchers. They're also super desperate because they left the European Union and that is also having a terrible effect on the economy. Copying the UK is not a clever idea.

Re: Quebec bans unvaccinated from buying groceries at Walmart, Costco

#10
post #6
post #2

The public policy responses to this pandemic would make a whole lot more sense if intramuscular (humoral) vaccination actually prevented (or even significantly mitigated) the spread of sars-cov-2. Unfortunately humoral vaccination only starts the B cell to plasma cells training and generation of igG antibodies in the body serum to protect internal organs. Other immune compartments like the upper respiratory mucosa ar…

Quebec has a heavily socialized medical system. 10% of the population is unvaccinated, but make up >50% of COVID beds in hopitals, a significant fraction of the *entire medical system*. At some point the other 90% of taxpayers shouldn't subsidized the stupid decisions of the remaining 10%. I'm not saying banning grocery store access is necessarily it, but something needs to be done

>At some point the other 90% of taxpayers shouldn't subsidized the stupid decisions of the remaining 10%.

The idea that vaccinated people are an island unconcerned with the fate of the un-vaccinated or the spread of the disease breaks down in two places:

1. You can still die from it if you have the shot, you're just substantially less likely to.

2. Eventually, unless they're stopped, random mutations will create a virus that the vaccine doesn't help with at all.

Honestly, the fact that the virus is running around replicating in a way that's constantly exposed to anti-vaccination selection pressure (both from trying to jump out of the un-vaccinated reservoir to vaccinated people and replicating to a limited extent in the presence of vaccine-primed immune systems) is in some ways a worst-case-scenario. It would be hard to intentionally design a vaccine escape guided evolution experiment more effective than what we've created in the world today.

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