Live data from Hacker News

A $3B bet on finding the fountain of youth

economist.com

61–70 of 214 posts

Re: A $3B bet on finding the fountain of youth

#61

Earlier quoted context omitted.

You are forgetting the iron law of real-life business stories: the better they seem, the worse they are.

>the better they seem, the worse they are Is this common knowledge? I've seen it empirically but I don't know how much is that a widespread feeling. (Not being snark or sarcastic).

I suspect the recent Elizabeth Holmes conviction of investor fraud at Theranos might contribute to the idea of flashy names propping up an unsustainable idea (e.g. with so many high-ranking names in the US military establishment previously supporting the company).

I'm not aware of other recent high-profile examples, though I would be interested in learning about them.

Re: A $3B bet on finding the fountain of youth

#62

Earlier quoted context omitted.

>the better they seem, the worse they are Is this common knowledge? I've seen it empirically but I don't know how much is that a widespread feeling. (Not being snark or sarcastic).

I suspect the recent Elizabeth Holmes conviction of investor fraud at Theranos might contribute to the idea of flashy names propping up an unsustainable idea (e.g. with so many high-ranking names in the US military establishment previously supporting the company). I'm not aware of other recent high-profile examples, though I would be interested in learning about them.

Every high-profile failure of the last century fits the bill, because bad business teams cannot get invested in, by definition, without looking good.

Good business teams tend to be good in the details, which leads to them struggling to find willing audiences.

Re: A $3B bet on finding the fountain of youth

#63
post #59

Trying to fix aging for existing humans is like trying to patch a binary that's already running, it would be way easier to build new humans with better source code imo.

But that does nothing to save the rich bastards funding it from dying.

Death sucks, but I’m not sure indefinite life extension is a great idea for humanity at large.

Re: A $3B bet on finding the fountain of youth

#64

“A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents die, and a new generation grows up that is familiar with it.” – Max Planck[1] Often paraphrased as "Science progresses one funeral at a time." I don't think we really want immortality or unnatural longevity. [1] https://en.wikipedia.org/wiki/Planck%27s_principle

You might not. Sign me up. Maybe just maybe if people live longer, they will be more likely to change their beliefs over time.

Re: A $3B bet on finding the fountain of youth

#65
post #8

This all feels like the Ocean's 11 version of biotech The straight laced CEO as foil with an amazing reputation and a ticking biological clock (1) The mad scientist known for mixing human and monkey embryos (2) The beautiful and brilliant husband & wife whiz kid team (3) All funded by the secretive Russian billionaire with questionable fortune originations (4) Grabbing the popcorn (1) https://altoslabs.com/team/execu…

To be fair: there are some areas of research [0][1] which cannot but help sound like fantasy.

Even were they to be pursued with the utmost rigor. Which by definition they can't be, because the very people and institutions required to do so would shy away because it's too fantastic of an endeavor.

So here's to the dreamers! It's your (Russian oligarch) money, break a leg!

[0] https://en.m.wikipedia.org/wiki/Biosphere_2

[1] https://www.nytimes.com/2019/07/02/magazine/dead-pig-brains-...

Re: A $3B bet on finding the fountain of youth

#66

People have been trying to “cure cancer” for a while, and though there is some success, we have many more cure for mice, no? However, I have not heard of even a 10 year old lab mouse that has the health of a young mouse. Isn’t that a bad sign we can’t even slow aging (beyond fractional amounts) in a mouse?

This reasoning depends on how much effort has gone into the two goals.

Cancer therapies are a proven business model, so a lot of R&D funding has been poured into searching for them.

I'm not sure how comparably much has gone into slowing mouse aging.

Re: A $3B bet on finding the fountain of youth

#67
post #5

There's nothing Silicon Valley billionaires will throw money at faster than the ability to live longer/forever. Makes sense in a way, but pretty much everyone in the field will tell you that the science is simply not there yet. Calico is similarly funded and has been at it for a decade now, with nothing to show for it.

The science is there, but there has actually been a stigma against generalized life extension research because that particular project has been the purview of cranks for literally thousands of years.

Re: A $3B bet on finding the fountain of youth

#68
post #63
post #59

Trying to fix aging for existing humans is like trying to patch a binary that's already running, it would be way easier to build new humans with better source code imo.

But that does nothing to save the rich bastards funding it from dying. Death sucks, but I’m not sure indefinite life extension is a great idea for humanity at large.

Yeah, indefinite life extension sounds like a fools bet. However, extending the human body's abilities in order to enjoy old age better would be something I wouldn't mind.

Re: A $3B bet on finding the fountain of youth

#69
post #63
post #59

Trying to fix aging for existing humans is like trying to patch a binary that's already running, it would be way easier to build new humans with better source code imo.

But that does nothing to save the rich bastards funding it from dying. Death sucks, but I’m not sure indefinite life extension is a great idea for humanity at large.

It will definitely cripple progress. Even with our current lifespans we see past generations blocking progression with their death grips on powerful positions

Re: A $3B bet on finding the fountain of youth

#70

“A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents die, and a new generation grows up that is familiar with it.” – Max Planck[1] Often paraphrased as "Science progresses one funeral at a time." I don't think we really want immortality or unnatural longevity. [1] https://en.wikipedia.org/wiki/Planck%27s_principle

I'd definitely want immortality in the sense of stopping physical (and mental) deterioration. You can always just commit suicide if you're done. I discuss this with friends and family occasionally, and they all seem to have these ideas that we're "only supposed to live 100 years or so". But that seems like a logical fallacy (appeal to nature) to me, it's not an actual argument. And sure, there are plenty of dystopian…

There's the problem of the elderly continuing to accumulate wealth and power without ceding any to the younger generations.

It's already happening. Look no further than the geriatric US lawmakers and how out of touch they are with the future.

Post reply on HN