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Israel Finds Fourth Covid Booster Is Ineffective

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31–40 of 272 posts

Re: Israel Finds Fourth Covid Booster Is Ineffective

#31
post #3

Ineffective for Omicron . It still helps immunity in general, so is recommended for immunocompromized people and others with low immunity, most people don't need it though, the gain isn't enough to matter for them.

What is "immunity in general" for you ? This shot is not vitamin C

Presumably they are referring to other strains of COVID rather than say AIDS.

I don’t know if that’s true or false, but it’s best to take peoples statements in a reasonable context.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#32

I am living in Israel, i doubt that it is possible to state anything definitively on the subject: regulations and decissions are being changed on a daily basis. I am not a healthcare specialist, however all this is giving the impression of being one big mess...

That's how science works: when the facts become updated you update your decisions. Israel has been among the most science-driven governments in Covid policy. I'm not really sure why your "impression" should be mentioned given that you expressly state that you're not a specialist.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#33
post #5

There are two separate questions: Does an extra booster prevent infection? Does an extra booster reduce hospitalizations and deaths? Seems this study only addressed the first question. But instead of giving a fourth shot based on the OG Covid, seems an updated version based on omicron, delta, and any new variants of concern would be a better idea.

I can't for the life of me understand why your last statement isn't what the world is driving for at the moment. mRNA vaccines are easily(-ish) updated, so punch out an Omicron specific dose and get on with the regular single/dual (if needed) regime. It seems strange we'd opt for 3-4-5 shots given the benefit of mRNA was its ease of creation and modification.

Given what happened with delta, it seems likely that by the time a variant-specific booster is ready (i.e. gone through safety trials and bureaucratic approval and have manufacturing lines switched over), the variant will already have come and gone.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#34

Record cases across the planet regardless of vaccination rates...how much longer until official sources are willing to acknowledge that these vaccines are not nearly as effective as claimed? How long before official sources acknowledge that breakthrough cases are probably drastically underreported? I can't be the only one surrounded by fully vaccinated individuals testing positive. Its happening far too often for me…

"Testing positive" isn't the main question.

Are they dying? Are they in the ICU?

And those officials that you distrust so much have been quite upfront about the fact that vaccines aren't all that effective against infection with Omicron. But they are quite effective against death and serious disease. Fauci's own words are that "just about everybody" will get infected.

If you want anecdotes, at least talk to an ICU nurse. Ask what they are seeing regarding vaccinated or unvaccinated.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#35

If I understand correctly, israel mandates a third shot (to do normal stuff), as do many places in north america, either now or soon. And I can only imagine many people would be happy to mandate a fourth as soon as possible. What I find most frustrating is that politicians are happy to make these mandates live, during an ongoing situation where we actually don't know a lot about how effective things are (and in the c…

> When was the last time anyone actually trusted a government?

My feeling is that people trust the government to the extent it does things their perceived enemies dislike. It's not about evaluating what's good for yourself or others; just knowing that your enemy dislikes it is a good enough signal that it's the right thing to do. Also, if your perceived enemy likes something that happens, that means it was automatically a wrong thing to do.

The government is just a cudgel each side uses against the other. And each side adds nails to the cudgel each time they possess it, even though they know its possession is likely to return to the enemy.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#36

If I understand correctly, israel mandates a third shot (to do normal stuff), as do many places in north america, either now or soon. And I can only imagine many people would be happy to mandate a fourth as soon as possible. What I find most frustrating is that politicians are happy to make these mandates live, during an ongoing situation where we actually don't know a lot about how effective things are (and in the c…

If you’re in the US, the federal vaccine mandate was quashed by the Supreme Court, so no need to be terrified.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#37

Record cases across the planet regardless of vaccination rates...how much longer until official sources are willing to acknowledge that these vaccines are not nearly as effective as claimed? How long before official sources acknowledge that breakthrough cases are probably drastically underreported? I can't be the only one surrounded by fully vaccinated individuals testing positive. Its happening far too often for me…

Then you have not been reading a single thing coming from the official sources because nobody has stated that vaccines do much against mild disease in Omicron, but they do prevent the hospital system from being saturated with cases and drastically reduce death rates.

If at this point you're not aware of this, which has been repeated over and over again in media, you should reconsider your sources of information.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#38
post #15

> the amount of antibodies returns to the level it was after the third vaccine, not more. It’s nice, but it’s not what we expect from a booster So basically it doesn’t confer any long term benefits - the only value from it would be if you want to keep your circulating antibodies high by perpetually boosting on a regular interval.

It remains to be seen over the long-run whether antibody levels correlate inversely with either risk of: a) _any_ Covid infection or b) _severe_ Covid infection.

Antibody levels are often cited as prediction surrogates early on because they are easy to measure. Occurrence or recurrence of infection, irrespective of antibody levels, of course, takes time. Also remaining to be seen is the role of T-cell mediated immunity in reducing the severity of Covid infection. If that role is significant, then declining antibody levels may be less worrisome than people believe currently.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#39

If I understand correctly, israel mandates a third shot (to do normal stuff), as do many places in north america, either now or soon. And I can only imagine many people would be happy to mandate a fourth as soon as possible. What I find most frustrating is that politicians are happy to make these mandates live, during an ongoing situation where we actually don't know a lot about how effective things are (and in the c…

> and in the case of the latest variant, we know they are not effective

I assume you are talking about stopping spread, which could be accurate. I further assume you are not referring to reducing illness severity, because they obviously are effective at that. But that benefit extends beyond the individual insofar as it reduces strain on the overall healthcare system -- ensuring that even those who have injuries or illnesses that have nothing to do with the disease in question receive adequate care. Therefore a vaccine mandate (or restrictions placed upon those who aren't vaccinated) can still be justified.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#40
post #23

Earlier quoted context omitted.

I can't for the life of me understand why your last statement isn't what the world is driving for at the moment. mRNA vaccines are easily(-ish) updated, so punch out an Omicron specific dose and get on with the regular single/dual (if needed) regime. It seems strange we'd opt for 3-4-5 shots given the benefit of mRNA was its ease of creation and modification.

I think they are making these strain specific boosters. But it seems “they”* want to keep it quiet until they are ready to release them. My first through on this is that there is over-supply of the OG vaccine and it takes time to switch production and the booster story is designed to give some hope and confidence to the masses (which is good I think). There is also some paperwork involved which takes time, but as we…

Over-supply? A lot of third world countries would be happy to take it. We're still far from offering the entire world even their first shot
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