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New‐onset autoimmune phenomena post‐Covid‐19 vaccination

onlinelibrary.wiley.com

1–10 of 164 posts

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#4
post #2

is anyone able to explain this in plain english please ?

I'm not an immunologist, but skimming through this it seems to describe patient cases who developed auto-immune disorders after - not necessarily because of - a mRNA covide vaccine, and describes possible causal chains in the immune system.

Since these cases emerged within a month, it seems to describe extremely rare side-effects rather than anything widespread but as of now yet unknown.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#5
post #2

is anyone able to explain this in plain english please ?

It's a catalogue of potential side effects. What they don't state is frequency, and variance from normal population. Nor do they discuss viral risks of the same diseases.

Basically it's saying "this can happen" and that's useful but it would have helped enormously if they had said how many instances in what size cohorts.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#8
post #7

Anyone that's worried about autoimmune phenomena after vaccination should look at autoimmune phenomena post Covid infection

Isn't cytokine storm in the late stage of corona infection exactly that?

Kinda, but I'm not sure if it fits the autoimmune definition or just a runoff immune response (but still against the antigens)

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#9
post #2

is anyone able to explain this in plain english please ?

This meta-study summarises various studies that look into reported cases of auto-immune problems after vaccination.

Most of these are in the order of 1-2 cases per million vaccine doses, and often close to the natural background rate of these problems manifesting in otherwise healthy individuals: If you look at 100,000 people for a year, you expect 2 of them to contract Guillain–Barré syndrome naturally, 1 to develop blood clots, etc. pp.

So the various studies also determine if there even is a statistically significant increase or not, which there sometimes is, sometimes isn't. The meta-study summarises all that.

And even taken together, all the various problems are not significant enough to counterindicate any of the vaccines, given just how much more dangerous covid infections are:

> Although allergic reactions to vaccines are rare, as vaccination programmes are being rolled out globally, many vaccine-related side-effects are being reported. Importantly, we do not aim to disavow the overwhelming benefits of mass vaccination with COVID-19 in controlling COVID-19 pandemic and preventing COVID-19 morbidity and mortality. We encourage and support COVID-19 vaccination globally to create an immunity barrier among population.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#10
post #5
post #2

is anyone able to explain this in plain english please ?

It's a catalogue of potential side effects. What they don't state is frequency, and variance from normal population. Nor do they discuss viral risks of the same diseases. Basically it's saying "this can happen" and that's useful but it would have helped enormously if they had said how many instances in what size cohorts.

The individual studies they're referencing do that. Overall, there's a risk, but it's negligible with sufficient monitoring.
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