Earlier quoted context omitted.
If I could make a 100x profit on my time doing it, you bet. To put more forcefully: if I needed to maintain one of those room sized refrigerators, and could save $10,000 for a couple hours of messing with a compressor the decision is a no brainer. I agree that mortals can't/won't do this -- doesn't mean the HN crowd is being intelligent when they say what the guy I replied to was saying :p EDIT: Downvoters, please ex…
Someone with high computing requirements shouldn't be using an ultra light notebook; get a desktop or get an amazon ec2 instance for a few pennies.
The EC2 option has always interested me, but short of EBS RAID its IO actually isn't better than a vertex 3 -- they're crazy fast; if you haven't tried them I highly recommend you do :)