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Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

medrxiv.org

131–140 of 207 posts

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#131
post #129
post #100

Earlier quoted context omitted.

I saw a statistic of Denmark (who are aspirating) vs Norway (who aren't), and vaccine complications[0] were something like 1 in 25.000 in Denmark vs 1 in 15.000 in Norway[1], so there was a clear difference. [0] Or myocarditis specifically? [1] Don't quote me on these numbers, they are ballpark numbers from my memory

isnt that backwards from the expectation?

Yes you're right, my bad, edited (switched the numbers around).

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#132
It seemed likely early on that the risks of vaccination exceeded the benefits for healthy young people, but the argument was they should get vaccinated anyway so they wouldn't be able to transmit the virus to someone more vulnerable. Now that it's clear vaccination doesn't prevent transmission, the argument for vaccinating healthy young people is pretty weak.

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#133
post #57

Earlier quoted context omitted.

> This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this. This is especially fascinating to me because for months I noticed that whenever I or anyone else would bring up the fear of myocarditis from the vax (w…

This preprint agrees that the risk of myocarditis is significantly higher, except if you are a. A male b. Under 40 years old c. Took the Moderna vaccine So the statement that COVID has a higher risk of myocarditis is still true. The media and those people got their information from existing data. This data was correct for the original question. However it wasn't delineated by age and by vaccine, and it's only after t…

> So the statement that COVID has a higher risk of myocarditis is still true.

Yes but it's misleading, and whether or not you want to argue it's deliberately so, is another debate. Are men under 40 who are considering Moderna (or don't even know what vax they're going to get since both are considered fairly equal) not worthy of being informed that their risk of myocarditis is actually potentially higher than if they got COVID? That doesn't make much sense to me, if it does to you then at what threshold would they be worthy of being informed that the blanket statement that's been being thrown around, doesn't actually apply to them? I seem to recall most people arguing that "COVID isn't actually that bad" not having an acceptable argument because while it's true for many people, for other groups of people, COVID actually is bad...

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#134

Earlier quoted context omitted.

I don't know. I feel that many people got unfairly labelled as "anti-vaxxer" because they simply opposed to forced vaccination --not the efficacy of the vaccine itself, based on the argument that risk of death from covid was relatively very low for healthy adults and children. And given the time constrains for the vaccine production and trials, it would have been prudent to assume that the side effects associated wit…

> I don't know. I feel that many people got unfairly labelled as "anti-vaxxer" because they simply opposed to forced vaccination Unlikely because the most of the same people chose not to get vaccinated themselves well before any mandates or requirements came into force, and were posting arguments online warning people not to get the vaccine or that it hadn't been sufficiently tested - as you yourself do in this post.…

> and were posting arguments online warning people not to get the vaccine or that it hadn't been sufficiently tested - as you yourself do in this post.

As did many news media organizations - only up until the election, that is. [0] Then everyone was a conspiracy theorist immediately after.

[0]: https://www.cnn.com/2020/09/01/health/eua-coronavirus-vaccin...

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#135
post #72
post #57

Earlier quoted context omitted.

> This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this. This is especially fascinating to me because for months I noticed that whenever I or anyone else would bring up the fear of myocarditis from the vax (w…

They might still be right; this is only a pre-print, only focused on one specific aspect of COVID and the effect size is small. But if they are wrong, the most likely explanation is they misunderstood something and were just wrong. Ironically, as is well known but bears repeating, the vocal "follow the science" types tend more to be believers in authority figures than people who care what science says. They aren't es…

> the most likely explanation is they misunderstood something and were just wrong

I think you're giving the media far too much credit especially when it comes to this issue. Remember, this is a media that actively called a legitimate, low-side-effect profile, WHO-listed essential drug "horse paste" or at least actively made comparisons to it, and a media that sowed fear and doubt about the vaccine while Trump was still President.

I think the time is long gone for giving the media the benefit of the doubt on things like this. Scientists sure, but the media, absolutely not.

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#136
post #94

Earlier quoted context omitted.

Quoted post unavailable.

> This is not peer reviewed With Covid moving so fast it's not really feasible to rely on peer-reviewed data alone. Once a paper gets reviewed things have usually changed (like new variants). Pre-prints are very necessary because of this. Of course it's not optimal, you either have unreliable or outdated data.

No post body was provided.

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#137

Do they know why the shot skyrockets myocarditis risk mostly among young men? Like what's the mechanism?

I've heard one semi plausible theory so far.. but take it with a huge grain of salt because of the theorists reputation.

Peter McCullough in his recent Joe Rogan interview suggested it may be due to the mRNA vaccines nano lipids. He said the heart, brain, and reproductive organs are "sponges" for the nano lipids. Thus these organs are getting exposed to more spike proteins than else where in the body. The damage from spike proteins is otherwise well documented.

2 questions we can use to vet this: 1. are there significant cardiovascular differences between genders, and 2. Do we see significantly more myocarditis in Pfizer vs astrazeneca.

Other than that I don't have enough medical knowledge to dispute it, but no one seems to have picked up on it in the medical community.

If it's not something that can be quickly dismissed on first principles then I think it would an interesting area to study.

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#138
post #106

Yeah but what's my risk of actually catching covid-19 vs. 100% if I just walk into my pharmacy and ask for the shot.

100% chance of what exactly?

Getting injected/exposed/transfected with the vaccine.

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#139

Wasn't there a none live attenuation vaccine coming to market that doesnt use MRNA? I read myocarditis is partly caused by the mechanisms of producing the spike protein. Can't we just go back to traditional vaccines?

"Traditional vaccines" are by no means free of side effects. The smallpox vaccine is a live vaccine and causes much more severe side effects than mRNA COVID-19 vaccines, including myocarditis [1]. This risk was accepted since smallpox is incredibly dangerous.

Inactivated vaccines appear to be quite ineffective against severe COVID and I have read that experts are doubtful about long-term protection against severe cases as well.

One alternative might be recombinant protein vaccines like the one from Novavax. This one was just approved in the EU and apparently the phase-3 trial went well. Of course, rare side effects (like myocarditis in mRNA vaccines) can only be measured once at least a few million people have been vaccinated. Also the longevity of the protection is still unknown.

[1] https://jamanetwork.com/journals/jama/fullarticle/201967

Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]

#140
post #139

Wasn't there a none live attenuation vaccine coming to market that doesnt use MRNA? I read myocarditis is partly caused by the mechanisms of producing the spike protein. Can't we just go back to traditional vaccines?

"Traditional vaccines" are by no means free of side effects. The smallpox vaccine is a live vaccine and causes much more severe side effects than mRNA COVID-19 vaccines, including myocarditis [1]. This risk was accepted since smallpox is incredibly dangerous. Inactivated vaccines appear to be quite ineffective against severe COVID and I have read that experts are doubtful about long-term protection against severe cas…

> This risk was accepted since smallpox is incredibly dangerous.

In particular, it was way more dangerous than COVID is. To figure out an acceptable level of side effects, wouldn't it be better to compare COVID to other diseases of a similar danger level?

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