Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
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Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#2This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this.
It reads:
> Despite more myocarditis events occurring in older persons, the risk following COVID-19 vaccination was largely restricted to younger males aged less than 40 years, where the risks of myocarditis following vaccination and infection were similar. However, the notable exception was that in younger males receiving a second dose of mRNA-1273 vaccine, the risk of myocarditis was higher following vaccination than infection, with an additional 101 events estimated following a second dose of mRNA-1273 vaccine compared to 7 events following a positive SARS-CoV-2 test.
This guy made a graph of their data, which makes it a little more clear:
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#3This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this. It reads: > Despite more myocarditis events occurring in older persons, the risk following COVID-19 vaccination was largely restricted to younger males a…
That graph in that tweet is included in the study's PDF. It's the very last page of the PDF and has more graphs too.
I wish the study's age group was more specific (the authors admit they don't have enough data for the 13-17 age group to make it more specific). Aka, I would like to see 10 year age group intervals. From other studies, the risks is highest in 16-24 if I remember right?
There's a study out of Public Health Ontario, ON, Canada which compares the risks depending upon the intervals between first and second dose.
https://www.medrxiv.org/content/10.1101/2021.12.02.21267156v...
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#4Do they know why the shot skyrockets myocarditis risk mostly among young men?
Like what's the mechanism?
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#5This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this. It reads: > Despite more myocarditis events occurring in older persons, the risk following COVID-19 vaccination was largely restricted to younger males a…
> This guy made a graph of their data, which makes it a little more clear:
As another commenter as has pointed out, the graph in question in included in the PDF version of this preprint (which you can see here: https://www.medrxiv.org/content/10.1101/2021.12.02.21267156v...).
I want to add: "this guy" is Vinay Prasad, a professor of oncology at UCSF and an incredibly prescient thinker through the COVID-19 pandemic, and someone with whome I've had the joy to correspond and repeatedly be impressed by his straightforward, evidence-based, dry-witty way of thinking, writing, and speaking.
He's a significant up-and-come in medical science, without a doubt, and someone to follow if you are interested in science-based policy.
We had the pleasure of hosting an AMA with him on /r/lockdownskepticism which you may find enjoyable and educational: https://www.reddit.com/r/LockdownSkepticism/comments/m0ll33/...
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#6> In summary, the risk of hospital admission or death from myocarditis is greater following COVID-19 infection than following vaccination and remains modest following sequential doses of mRNA vaccine including a third booster dose of BNT162b in the overall population.
> However, the risk of myocarditis following vaccination is consistently higher in younger males, particularly following a second dose of RNA mRNA-1273 vaccine.
This is an important reminder for policy makers and the public that vaccination policy cannot be reduced to a simple dichotomy.
Vaccines can be beneficial for the overall population AND present excess risk for certain sub-populations. Stratifying by age and sex is essential for discussions on this topic to be accurate and productive.
Moreover, it takes a long time and a large sample size for these anomalies to be detected with significant statistical power. Let's do our best to avoid frustrated bickering, we need all the patience and empathy we can muster.
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#7Do they know why the shot skyrockets myocarditis risk mostly among young men? Like what's the mechanism?
The spike protein RNA vaccine saturates the body causing an inflammatory response especial so in certain muscles that use lipids (vaccine contains lipid as a transport mechanism) as a primary source of energy such as the heart muscle. A good interview of this is [1] Joe Rogan Experience episode #1747 - Dr. Peter A. McCullough
[1] https://open.spotify.com/episode/0aZte37vtFTkYT7b0b04Qz
Edit: [2] The CDCs myocarditis page on this since the Dr. McCullough is upsetting people here. And just so to pre-emptively dismiss any attacks that I am anti-vax I am fully vaxed and boosted. But talking about side effects or risks apparently puts one in said camp. Nuance is dead.
[2] https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/my...
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#8Do they know why the shot skyrockets myocarditis risk mostly among young men? Like what's the mechanism?
Could puberty and high testestorone have something to do with it? Just making a guess because it's specifically higher in 16-24 group.
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#9Do they know why the shot skyrockets myocarditis risk mostly among young men? Like what's the mechanism?
The spike protein RNA vaccine saturates the body causing an inflammatory response especial so in certain muscles that use lipids (vaccine contains lipid as a transport mechanism) as a primary source of energy such as the heart muscle. A good interview of this is [1] Joe Rogan Experience episode #1747 - Dr. Peter A. McCullough [1] https://open.spotify.com/episode/0aZte37vtFTkYT7b0b04Qz Edit: [2] The CDCs myocarditis p…
The 30 micrograms of ribonucleic acid in an mRNA vaccine dose get folded into protein and make their way into the lymph nodes in your armpit. They do not “saturate the body”.
Joe Rogan interviews are not a reliable source of medical information. Rogan is a COVID conspiracy theorist of the “just asking questions” variety. For anyone unconvinced about this, and values diversity of opinions in their media diet, the recent episode of Decoding the Gurus is worth a listen.
https://decoding-the-gurus.captivate.fm/episode/joe-rogan-ju...
Re: Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]
#10Do they know why the shot skyrockets myocarditis risk mostly among young men? Like what's the mechanism?
The spike protein RNA vaccine saturates the body causing an inflammatory response especial so in certain muscles that use lipids (vaccine contains lipid as a transport mechanism) as a primary source of energy such as the heart muscle. A good interview of this is [1] Joe Rogan Experience episode #1747 - Dr. Peter A. McCullough [1] https://open.spotify.com/episode/0aZte37vtFTkYT7b0b04Qz Edit: [2] The CDCs myocarditis p…
It saturates the body to such a degree that the "worst" vaccine in the "worst" age group creates an extra 30 cases of myocarditis per million people?
Edit: 100 per million, thanks for the correction. 0.01% of people.