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Children develop robust and sustained cross-reactive immunity after Covid

nature.com

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Re: Children develop robust and sustained cross-reactive immunity after Covid

#2
Finally some glimmers of hope in moving past Covid.. if Omicron continues on its current track of highly infectious but less serious —- and infection confers reactive immunity to a variety of strains, we could be closer to the endemic but manageable end game. Good vaccines + mild severity illness are basically the best case.

What a stroke of luck that we are here vs a more infectious strain of Delta or some other nightmare that would keep this rolling.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#3
So the long Covid we’ve been afraid of for our children this whole time has actually been long term immunity? How ironic that our own push to vaccinate and save our children could put them in a worse position immunity-wise. Like rain on your wedding day.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#4
post #3

So the long Covid we’ve been afraid of for our children this whole time has actually been long term immunity? How ironic that our own push to vaccinate and save our children could put them in a worse position immunity-wise. Like rain on your wedding day.

Biochemist here: your claim that vaccination puts children in a worse position is neither supported by this paper, nor substantiated by any other data point to the best of my knowledge.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#5

Finally some glimmers of hope in moving past Covid.. if Omicron continues on its current track of highly infectious but less serious —- and infection confers reactive immunity to a variety of strains, we could be closer to the endemic but manageable end game. Good vaccines + mild severity illness are basically the best case. What a stroke of luck that we are here vs a more infectious strain of Delta or some other nig…

Indeed! I really hope governments will start recognising this and give us back our freedom. Media messages and restrictions are still pretty negative, despite the lack of severity. I don't know how can they talk about another lockdown.

Delta also had lower mortality than the first wave: this was confirmed by some fact-checkers and not by others (depending on how alarmist the fact-checker is) but looking at numbers, it does seem to be case.

It seems to be an evolutionary trend where the virus mutations that are successful became more transmissible and less deadly (probably because a dead host doesn't spread as much as an alive one).

Re: Children develop robust and sustained cross-reactive immunity after Covid

#6
Biochemist opinion: somewhat speculative, but what I take from this is that immunity in children makes them less likely than adults to shift from 'removed' to 'susceptible', in the SIR model. [1]

[1] https://en.wikipedia.org/wiki/Compartmental_models_in_epidem...

Re: Children develop robust and sustained cross-reactive immunity after Covid

#7
post #4
post #3

So the long Covid we’ve been afraid of for our children this whole time has actually been long term immunity? How ironic that our own push to vaccinate and save our children could put them in a worse position immunity-wise. Like rain on your wedding day.

Biochemist here: your claim that vaccination puts children in a worse position is neither supported by this paper, nor substantiated by any other data point to the best of my knowledge.

I think his point is that the immune response from the vaccine is lower than from just getting covid and the risks from getting covid for children are really low.

Still, I don't think it makes much of a difference either way, especially for kids who don't have much to fear from covid.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#8
post #4

Earlier quoted context omitted.

Biochemist here: your claim that vaccination puts children in a worse position is neither supported by this paper, nor substantiated by any other data point to the best of my knowledge.

I think his point is that the immune response from the vaccine is lower than from just getting covid and the risks from getting covid for children are really low. Still, I don't think it makes much of a difference either way, especially for kids who don't have much to fear from covid.

"immune response from the vaccine is lower than from just getting covid"

{{citation needed}}

My point is that this is unsubstantiated.

And it does make a big difference, because this reduces the likelihood of children going through multiple periods of infectivity: the fewer times children are infectious to others, on average, the more herd immunity we have, collectively, against SARS-CoV-2.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#9
post #8

Earlier quoted context omitted.

I think his point is that the immune response from the vaccine is lower than from just getting covid and the risks from getting covid for children are really low. Still, I don't think it makes much of a difference either way, especially for kids who don't have much to fear from covid.

"immune response from the vaccine is lower than from just getting covid" {{citation needed}} My point is that this is unsubstantiated. And it does make a big difference, because this reduces the likelihood of children going through multiple periods of infectivity: the fewer times children are infectious to others, on average, the more herd immunity we have, collectively, against SARS-CoV-2.

No post body was provided.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#10

Finally some glimmers of hope in moving past Covid.. if Omicron continues on its current track of highly infectious but less serious —- and infection confers reactive immunity to a variety of strains, we could be closer to the endemic but manageable end game. Good vaccines + mild severity illness are basically the best case. What a stroke of luck that we are here vs a more infectious strain of Delta or some other nig…

The question ever since it became clear that this coronavirus was endemic has been what a "manageable end game" is: that is, what level of risk and mortality are we prepared to accept, given that deaths from Covid will never be zero.

This is, in my opinion, the primary underlying disagreement. Some people think that no amount of deaths from Covid is acceptable. Some people believe that even the peak pandemic mortality is acceptable. And others fall somewhere in between, by, for example, focusing on hospital capacity. I don't think there is any long-term solution to Covid as a social issue, something we talk about and can't move past, until some kind of consensus is reached on this.

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