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Japanese scientists develop vaccine to eliminate cells behind aging

japantimes.co.jp

281–290 of 382 posts

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#281
post #271

Earlier quoted context omitted.

Why do people need to die now more than ever ?

There's queues everywhere

If this technology is real it needs to be expensive enough to prevent the vast majority of people on earth from having access to it.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#282

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

> 2. I believe all governments should create Warpspeed for this approach. It wont be because of Govt but private business or a Uni maybe, you see if everyone lived a US lifestyle we need 4 planet earths, everyone living a UK lifestyle would required 2.5 planet earths, an EU lifestyle 2 planet earths, so do you see the problem if lifespans were increased any more than they currently are? Humans have exceeded the carry…

We'll just need to start living in VR. This will reduce the consumption of physical resources.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#283

Earlier quoted context omitted.

Gotta admit though, there has never been a better time to be a mouse.

Really? Because they get experimented on and then slaughtered by the thousands

Prior to that inevitable slaughter some of them get to experience things that most humans never get to experience.

Mice on MDMA for example could easily be having the best time that any mouse has ever had.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#284

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

>Imagine the massive GDP creation from making every 65+ year old feel 40 again. They'd work, consume, and generally flourish.

Yet another opportunity for boomers to fuck over their kids' generation by squeezing them out of the workforce again, and the lingering around longer than ever before, creating an unprecedented drain on social services that their children will have to pay for. Can't wait!

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#285
post #229

Earlier quoted context omitted.

> I believe all governments should create Warpspeed for this approach. What would that mean in practice?

Accelerated FDA approvals (willingness to grant EUAs), fewer blocks around human trials, even just having the FDA respond faster and more definitively would be a huge improvement over their current opaque processes (waiting weeks to even get a response to an email). Not to mention... funding.

Have you ever filed anything with the FDA? I have. The process is (understandably) cumbersome, but it is well described. I certainly don’t think communication is a barrier to drug development.

There are a lot of things that could be tweaked, but at a gross level it’s pretty consistent. In fact the recent, seemingly politicized, accelerated approval of aducanumab certainty caused a lot of turmoil and appears to have been a mistake.

When I was gestating my mother’s colleagues apparently couldn’t understand why she wouldn’t take the miracle drug thalidomide (much less even aspirin). Lucky for me! In general I think the medical side of FDA works reasonably well.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#287

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

The Red Mars series by Kim Stanley Robinson covers this in some detail. It's called the Longevity Treatment: https://www.kimstanleyrobinson.info/content/longevity-treatm...

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#288

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

In an ideal world. Even if we achieve longevity with this approach, we can't use it for everyone. People need to die now more so than ever, where would we put them otherwise? The whole idea behind the current pandemic is that people need to die, via vaccines, or the virus, or the media.

I rather see less babies.

I know it bad, but whenever I see a kid, I automatically think here's another person on this crowded plant we are ruining.

(And yes, I know the whole economic system might rely on having more kids, but maybe if there was a life extender adults could work more? Don't feel like a debate.)

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#289

Earlier quoted context omitted.

Really? Because they get experimented on and then slaughtered by the thousands

You forgot tiny detail that they live in prison for entire life eating equivalent of Mc Donalds or worse.

Sounds like suburb utopia.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#290

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

> Even if it's only 10 more years of quality life, this is the greatest good that could be done for humanity Why would that be your conclusion? It's 10 more years of life. It's not 10 more years of better life. It's a little more of the same. That 10 years is "experienced" as only a short increase in local time. Whereas before 33% of your life would have been 28 years old, afterwards 33% of your life would be at 31 y…

Tax those wealthy guys more. Tie all societal fees/fines to asset level. It might help?
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