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Japanese scientists develop vaccine to eliminate cells behind aging

japantimes.co.jp

81–90 of 382 posts

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#81

Sign me up for this the second it is available. As an aside, to spite anti vaxxers I’m on a mission to get every vaccine I can. I want my bloodstream to be like the Library at Alexandria before it burned down.

I’m with you. I’ve gotten vaccinated for everything my doctor lets me. Japanese Encephalitis? Pshaw. I don’t even know what it is, but good luck with my immune system. It’s like getting a superpower in a video game! And, vaccines have general positive effects of health: https://ec.europa.eu/research-and-innovation/en/horizon-maga...

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Re: Japanese scientists develop vaccine to eliminate cells behind aging

#82

Sign me up for this the second it is available. As an aside, to spite anti vaxxers I’m on a mission to get every vaccine I can. I want my bloodstream to be like the Library at Alexandria before it burned down.

You sound as if your mental capacity is severely limited.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#83

Sign me up for this the second it is available. As an aside, to spite anti vaxxers I’m on a mission to get every vaccine I can. I want my bloodstream to be like the Library at Alexandria before it burned down.

Did you get the rabies vaccine, yet? Also, the Dengvaxia is supposedly not recommended unless you've contracted Dengue already.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#84
post #32

> The team, including Juntendo University professor Toru Minamino, confirmed that mice administered with the vaccine showed decreases in the zombie cells, medically known as senescent cells, and in areas affected by arterial stiffening. By now this has become a trope. "Researchers develop new treatment for {UNTREATED_DISEASE}" ... in mice. Mouse models of human disease are very limited in their predictive ability. Th…

This is basic science; early research. Not immediately applicable, and harder for many people to see the benefit, but important. Humans share much fundamental biology with other mammals. Moue tests aren't guaranteed to be directly applicable, but it's what we've got.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#85
post #70
post #4

Earlier quoted context omitted.

It's probably not a good idea to get every single vaccines that's not recommended to you by the CDC/your doctor. Vaccines could potentially trigger some dangerous side effects, however rare it is.

Definitely. We have a tremendous amount of risk aversion these days and a culture that has disdain for risk, even calculated abstract risks. What many don't realize is being too risk averse comes with its own risks, it also requires accurate risk assessment so you can make the correct decisions on when to take a risk and not. You could lockup in complete fear akin to analysis paralysis where non-zero risk keeps you f…

We are very risk averse of taking vaccines, while they are incredibly safe and barely have any risk associated with them. Probably more harm is done because people are too afraid of taking a vaccine than the opposite (not only looking at covid19 vaccines). The biggest harm done by taking vaccines you don't really need is probably that the money could have been used for something more useful.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#86

Earlier quoted context omitted.

16 is too young and you won't be able to do a lot of things unless you walk around with paperwork all the time. 24 sounds good but I'd pick 30 cause looking 30 people take you a bit more seriously. You will be able to relate more with people in their 30swhen you are 50 but look 30 than with people in their 20s. Of course in this hypothetical scenario if everyone is not aging then it all cahnges.

Yeah, maybe a separate question would be what the age would be if everyone in society was forced to pause at that age. I wonder what immortal oligarchs would even do…

they’d find other ways to kill each other. that’s not facetious—our egos depend on getting an edge, however microscopic, over others, and when that doesn’t happen, we get angry (that is, desperate and irrational) and do things we shouldn’t. it’s a tale as old as time.

that ‘modern’, ‘developed’ civilizations haven’t devolved this way yet isn’t because we’re all so cultivated now, but because we’ve lived in an unusual period of extended growth and excessive abundance which keeps destructive competition at bay. but infighting (i.e., tribalism) has been rising over the past 50+ years and is threatening to overthrow that period of prosperity and civility.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#87
post #64

Earlier quoted context omitted.

You already have the Library of Alexandria. That's your lymph nodes. What vaccines do is move some books to the front of the building, so your dentritic cells don't have to spend a few days finding them. You want the right books at the front. A mission to move all the books to the front is perhaps misguided.

You have antibodies that will bind to just about anything foreign, including viruses that your body has never seen before, M-type immunoglobulin (IgM). It's the kind of antibodies that responds in the first phases of an infection. The problem is that IgMs are not very specific. They bind to a lot of things, but they bind poorly. In the library of Alexandria analogy, it's like a book that happens to mention a subject…

Is there a good resource to learn more about this without a Biology degree? I always assumed the body generated matching snippets at random and the law of large numbers would result in a match eventually.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#88

Earlier quoted context omitted.

Gotta admit though, there has never been a better time to be a mouse.

Really? Because they get experimented on and then slaughtered by the thousands

At least some get lucky and sometimes slow down aging - for example - when things work out.

I don't want to think about what the others go through when things go wrong, though...

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#90
post #27

Earlier quoted context omitted.

You already have the Library of Alexandria. That's your lymph nodes. What vaccines do is move some books to the front of the building, so your dentritic cells don't have to spend a few days finding them. You want the right books at the front. A mission to move all the books to the front is perhaps misguided.

I think it is more like the library of Borges, but with stuff that would interact with self culled.

We have an infinite library, but the literary criticism section has been carefully curated to remove all criticism of books in this library. The Library of Burges, though, we are happy to criticize unto oblivion.
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