I just zoom in to 115% on iOS and 120% in Firefox on my desktop computer.
On a desktop OS, you should not have issues using pointer devices. (On mobile devices, when using fingers to tap, one normally pinches to enlarge and re-pinches to adjust size... Although I am not really sure if this still works with nowadays' mobile software: I am assuming text reflow, being that strictly required, and last time I checked most implementations in browsers were broken.)
For comfort in readiing, on a desktop OS, one is supposed to quickly adjust the zoom level with [Ctrl]+[Wheel], or [Ctrl]+[+/-] or similar...