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Pfizer and Biontech provide update on Omicron variant

pfizer.com

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Re: Pfizer and Biontech provide update on Omicron variant

#2
This is the scientific meat of the press release where it claims a 25 times neutralizing antibody titers against the Omicron strain with a third dose of Pfizer-BionTech:

The sera were collected from subjects 3 weeks after receiving the second dose or one month after receiving the third dose of the Pfizer-BioNTech COVID-19 vaccine. Each serum was tested simultaneously for its neutralizing antibody titer against the wild-type SARS-Cov-2 spike protein, and the Omicron spike variant. The third dose significantly increased the neutralizing antibody titers against the Omicron strain spike by 25-fold. Neutralization against the Omicron variant after three doses of the Pfizer-BioNTech COVID-19 vaccine was comparable to the neutralization against the wild-type strain observed in sera from individuals who received two doses of the companies’ COVID-19 vaccine: The geometric mean titer (GMT) of neutralizing antibody against the Omicron variant measured in the samples was 154 (after three doses), compared to 398 against the Delta variant (after three doses) and 155 against the ancestral strain (after two doses). Data on the persistence of neutralizing titers over time after a booster dose of BNT162b2 against the Omicron variant will be collected.

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At the bottom of the press release it mentions that Pfizer is the marketing distribution partner for BionTech in many countries. Does anyone have a list where BionTech distributes directly?

"BioNTech is the Marketing Authorization Holder in the United States, the European Union, the United Kingdom, Canada and other countries and the holder of emergency use authorizations or equivalents in the United States (jointly with Pfizer) and other countries."

Re: Pfizer and Biontech provide update on Omicron variant

#8

Is "First Shot" "Second Shot" and "Booster" the same as 3 "doses"?

According to the CVS person who did my booster, the booster for Pfizer is a full dose while the Moderna booster is a half dose (relative to each manufacturer's original first and second shot doses).

Re: Pfizer and Biontech provide update on Omicron variant

#9
post #2

This is the scientific meat of the press release where it claims a 25 times neutralizing antibody titers against the Omicron strain with a third dose of Pfizer-BionTech: The sera were collected from subjects 3 weeks after receiving the second dose or one month after receiving the third dose of the Pfizer-BioNTech COVID-19 vaccine. Each serum was tested simultaneously for its neutralizing antibody titer against the wi…

IIRC Biontech distributes directly in some part of Europe that includes Turkey but I wouldn't bet on Kazakhstan and its neighbours. (Also, Pfizer does more than distribute, it also produces the stuff somewhere in the US, and contract manufacturers including Rentschler Biopharma produce for both of them.)
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