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Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

sciencealert.com

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Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#121

Post by conductr »

smackeyacky wrote: post #59
conductr wrote: post #22

Earlier quoted context omitted.

That’s the first thing that came to my mind, immediately followed by “I should tell my wife that it’s her fault if my semen turns to brain plaque” the next time she has a “headache”

Amazing! How are you posting from the 1950s?

Eh. Right on cue, I suppose. Because I married someone with a sense of humor. Maybe you can write a search engine to figure out what that is. Yes, that’s a throwback to when nerd jokes were a thing. I’ll throw this in so you you’re able to comprehend /s

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#122

Post by dang »

dotancohen wrote: post #89
yosito wrote: post #38

Earlier quoted context omitted.

According to my Garmin watch, sex with my girlfriend only gets my heart rate into the mid 90s, the same as a walk around the block. The significance of that data is up for interpretation, but I'm skeptical that sex is really a significant cardio activity.

> According to my Garmin watch, sex with my girlfriend only gets my > heart rate into the mid 90s You might want to try emrevarol's girlfriend. His Garmin watch reports she's good for the 160s.

Please don't do this here.

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#123

Post by [deleted] »

conductr wrote: post #22
d--b wrote: post #19

Is it just me or is there a sub text here that says: “maybe it’s not the drug, maybe a good shag every now and then does it, and viagra consumption is a good proxy for knowing that”?

That’s the first thing that came to my mind, immediately followed by “I should tell my wife that it’s her fault if my semen turns to brain plaque” the next time she has a “headache”

[deleted]

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#124

Post by hungryforcodes »

oliwarner wrote: post #109
hungryforcodes wrote: post #70

Earlier quoted context omitted.

It definitely has nothing to do with low sex drive. Isn't everyone using it now?

But why? My point is rather that if you don't want sex, you're not going to co-pay for a drug that helps you maintain an erection you've no interest in. If you do think everyone is popping these, I'd suggest this is maybe a side effect of years of being exposed to too much spam and way too much under-regulated pharmaceutical advertising. They're not without unwanted side effects, and again, don't overcome a disintere…

No side effects (for most people, especially using cialis) and fast, easy errections that you can maintain on demand for as long as you want. Mmmm...sounds just like 21st century progress to me.

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#125

Post by sneak »

q1w2 wrote: post #98
vidarh wrote: post #84

Earlier quoted context omitted.

We don't know any such things. Viagra has effects that could provide a plausible mechanism for a direct causal link. The article in particular points out that it directly interacts with amyloid and tau proteins, that are frequently implicated in Alzheimer's, and that they've explored it's effect on tau in vitro. That of course is not proof of a causal link, but it's enough to justify follow up research.

Viagra use indicates that the person has a partner(s) at an advanced age. This alone implies MANY lifestyle changes. What would be interesting would be a comparison again Cialis (the competitor to Viagra).

> Viagra use indicates that the person has a partner(s) at an advanced age.

Or money.

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#126

Post by dotancohen »

dang wrote: post #122
dotancohen wrote: post #89

Earlier quoted context omitted.

> According to my Garmin watch, sex with my girlfriend only gets my > heart rate into the mid 90s You might want to try emrevarol's girlfriend. His Garmin watch reports she's good for the 160s.

Please don't do this here.

I'll refrain. Thanks, dang.

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#127

Post by dotancohen »

tsol wrote: post #118
dotancohen wrote: post #103

Earlier quoted context omitted.

Perhaps nobody is joking about women being objects to be passed around. Perhaps we're no longer restrained by conventional ideas of institutionalized marriage and religion.

What? Respecting people's wives is a religious thing? Her point is valid, it is crass. Some people may like crass jokes, but I don't understand when some people refuse to admit they're crass

You are correct, it was crass. In moderation, a crass joke can sometimes be in taste. Whether this one was or not is in the eye of the beholder.

My contention was with the accusation that I had suggested "women being objects to be passed around". It seems to me that the GP could not fathom that a woman might have sex - or reject sex - by virtue of her own free will.

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#128

Post by wellthisisgreat »

james_burden wrote: post #111
Scoundreller wrote: post #25

Would be interesting to see what the effect with tadalafil is. Sildenafil is rather short acting while tadalafil is much longer acting. Tadalafil is also used in smaller but daily doses as a treatment for benign prostrate hyperplasia, so there should be more data on longer durations of use and effect. https://pubmed.ncbi.nlm.nih.gov/30901259/

I've been taking 5mg tadalafil/day for years. Super common in longevity/bbuilder circles. Lots of positive effects beyond dong gains.

Interesting. What kind of positive effects?

Also doesn’t tadalafil act for 36 or something like that hours?

Re: Viagra Is Linked to Almost 70% Lower Risk of Alzheimer's

#129

Post by vidarh »

q1w2 wrote: post #98
vidarh wrote: post #84

Earlier quoted context omitted.

We don't know any such things. Viagra has effects that could provide a plausible mechanism for a direct causal link. The article in particular points out that it directly interacts with amyloid and tau proteins, that are frequently implicated in Alzheimer's, and that they've explored it's effect on tau in vitro. That of course is not proof of a causal link, but it's enough to justify follow up research.

Viagra use indicates that the person has a partner(s) at an advanced age. This alone implies MANY lifestyle changes. What would be interesting would be a comparison again Cialis (the competitor to Viagra).

Hence why it requires further research before we can claim causality. My point was simply that assuming we "know" the causal link is something else is also unjustified without further research.

Especially given the size of the effect combined with the known interactions between Viagra and Tau proteins.

A comparison with Cialis might well be worth it down the line, but I don't see what it'd give before they've established whether or not there's a causal link.

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