Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

The epidemiological relevance of the Covid-vaccinated population is increasing

thelancet.com

Post reply on HN
Print view View original

21–30 of 55 posts

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#21

Post by csdvrx »

PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

> I hate that I’ve ideated suicide more in the past year than the previous 34 combined.

Ouch. What about a less "final" idea, like moving to the midwest or Texas?

Here we mostly don't care about such things, so it's business as usual!

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#22

Post by dataflow »

PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

> do you prefer the world as it is under coronavirus restrictions?

What present restrictions are you referring to? Could you list a few of the most onerous ones? I know there mask mandates in lots of places currently, and I know earlier in the pandemic there were severe restrictions on gathering indoors and such (and I'm not here to defend or condemn them), but what restrictions are there besides mask mandates that are currently causing you grief? I actually don't know. (Are you in the US? or is this about another country?)

I've been trying to guess them from the things you listed, but it's not clear to me, e.g. I don't quite know what restrictions are imposed on you that prevent you from having dinner with friends.

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#23

Post by [deleted] »

PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

[deleted]

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#24

Post by peppermint_tea »

PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

sorry to hear for your father. I do love remote meetings though, I can mute myself and go do something else.

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#25

Post by disambiguation »

sjwalter wrote: post #16
alevskaya wrote: post #8

Earlier quoted context omitted.

I used to work in immunology - this is not accurate. We know that e.g. mRNA vaccines elicit quite a good T-cell immune response. e.g. for one of many studies looking at T-cell responses to the recent sars-cov-2 vaccines: https://www.cell.com/immunity/fulltext/S1074-7613(21)00308-3

Why does vaccine-based immunity lack the durability of natural immunity?

Durability is an abstract quality, it could mean long lasting, or effective against variants, or some other resistance qualities..

IMO the science on natural immunity has been lacking, so it's hard to say with certainty.

one important thing we do know is that mRNA vaccines only generate an s-protein (the spike) whereas the full virus also includes an n-protein (the nucleocapsid). So vaccine immunity one trains against one protein whereas natural infections may train against both. This could be the basis for comprehensive immunity.. but I'll reiterate, it depends on scientific confirmation.

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#26

Post by PraetorianGourd »

dataflow wrote: post #22
PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

> do you prefer the world as it is under coronavirus restrictions? What present restrictions are you referring to? Could you list a few of the most onerous ones? I know there mask mandates in lots of places currently, and I know earlier in the pandemic there were severe restrictions on gathering indoors and such (and I'm not here to defend or condemn them), but what restrictions are there besides mask mandates that a…

I am in the US. Where I live masks are required indoors under all circumstances regardless of vaccine status. Indoor dining has been allowed for a few months now but there’s talk of introducing restrictions again.

It’s not so much how it is today, it’s the damage yesterday had done. And it’s the sword of Damocles that hangs over us all at the whisper of a new variant

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#27

Post by PraetorianGourd »

csdvrx wrote: post #21
PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

> I hate that I’ve ideated suicide more in the past year than the previous 34 combined. Ouch. What about a less "final" idea, like moving to the midwest or Texas? Here we mostly don't care about such things, so it's business as usual!

I’ve considered it.

I’m not in any way thinking of moving from ideation to realization. But ideation is scary enough

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#28

Post by vidoc »

peppermint_tea wrote: post #24
PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

sorry to hear for your father. I do love remote meetings though, I can mute myself and go do something else.

> I can mute myself and go do something else.

That's exactly what Jeffrey Toobin said as well :P

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#29

Post by PraetorianGourd »

peppermint_tea wrote: post #24
PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

sorry to hear for your father. I do love remote meetings though, I can mute myself and go do something else.

It is hard to understand what matters most in life, I’m glad you’ve found what really matters to you.

Re: The epidemiological relevance of the Covid-vaccinated population is increasing

#30

Post by renewiltord »

PraetorianGourd wrote: post #20

I mean this question with all respect. For those of you who error towards caution with COVID, do you prefer the world as it is under coronavirus restrictions? Again I am asking this with sincerity, if we could blink away COVID but keep the world as it is (remote work, limited travel, acceptable reason for isolation etc.) would you prefer that world? I hate the world COVID has created . I hate seeing everything throug…

It’s rubbish, isn’t it? But all that is past for most of us. I just came back from a bar in SF and I don’t think I wore a mask anywhere in it. Hung out with loads of friends. Had a great time.

SF is usually Restriction Central so it doesn’t seem like life is particularly bad now.

Personally, I rather like this interstitial time where the scared remain home and I am free to roam with my friends. Traffic and lines are better.

Post reply on HN