Live data from Hacker News

Two Triple Vaccinated Israeli Doctors Infected with Omicron

reuters.com

81–90 of 106 posts

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#81

The media really needs to slow their roll, a lot. Two people having breakthrough infections for any variant is not at all unlikely, and this is absolutely not evidence that Omicron is more likely to lead to breakthrough infections. In fact it would only be actually newsworthy if Omicron _didn’t_ break through. And the pointless emotional fact that they are doctors, as if any virus considers ones CV. And the excessive…

As a counterpoint I wonder how many thousands of lives we could have/would have saved if we reported on delta with the same type of urgency. We don't have the facts yet, and every story I've seen underscores that point. But to just say "we don't know so let's ignore it entirely until we do" seems to minimize the deadliness of the past mutations we've seen.

It is just as irresponsible to say “we don’t have all the facts… but it could render vaccines useless and reinfect everyone and spread like measles and kill like small pox”.

Ignoring it is irresponsible. Panicking is irresponsible. This isn’t a difficult or new concept! Each year the flu is a new “variant” and every single year it has the _potential_ to be 1918 all over again. But we don’t close borders and force quarantine until we have proof it isn’t 1918 bad. We study it, we prepare vaccines and we take reasonable precautions

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#82

Earlier quoted context omitted.

Air-travel is an essential service according to Canadian Air Transport Security Authority (Crown corporation). https://www.catsa-acsta.gc.ca/en/covid19-response You aren't allowed to air-travel without COVID shots. Is that not mandatory then? Also the courts have stated before that: > "at the very least, liberty must include those freedoms of lawful conduct always enjoyed by Canadians and by our predecessors in the A…

> This is inaccurate. Even in mild symptom cases, vaccinated and unvaccinated infections harbour the same levels of viral load. The Delta variant is able to grow in the noses of vaccinated people to the same degree as if they were not vaccinated at all and both groups can unknowingly and unwittingly transmit the virus for 3 days before experiencing any symptoms in 75% of the Delta variant infections. It's more nuance…

The data is all over the place. There's this peer reviewed study stated:

> "By analyzing viral loads of over 16,000 infections during the current, Delta-variant-dominated pandemic wave in Israel, we found that BTIs in recently fully vaccinated individuals have lower viral loads than infections in unvaccinated individuals. However, this effect starts to decline 2 months after vacci- nation and ultimately vanishes 6 months or longer after vac- cination. Notably, we found that the effect of BNT162b2 on reducing BTI viral loads is restored after a booster dose. These results suggest that BNT162b2 might decrease the infectious- ness of BTIs even with the Delta variant, and that, although this protective effect declines with time, it can be restored, at least temporarily, with a third, booster, vaccine dose."

https://www.nature.com/articles/s41591-021-01575-4.pdf

However, we also know that the viral loads are also very high in elders, in the obese, comorbidity as well as males. The drop in effectiveness happens the fastest in males, elderly and those with comorbidities.

Also expecting everyone to keep getting boosters every 2-6 months (Canada is allowing after 2 months) is entirely unreasonable.

There's other studies which found same viral loads in vaccinated vs unvaccinated even in mild cases (though it's not clear after what period did they perform the study).

Highly vaccinated Dane County in Wisconsin, US found no difference in viral loads when comparing unvaccinated to vaccinated infections, the viral load was consistent with the ability to shed infectious viruses.

https://www.medrxiv.org/content/10.1101/2021.07.31.21261387v...

Similarly, data from 36 Wisconsin counties found that both vaccinated and unvaccinated can transmit the infection. Infectious virus is found even in vaccinated when specimen Ct values are low, meaning mild cases in vaccinated individuals can spread the virus too.

https://www.medrxiv.org/content/10.1101/2021.07.31.21261387v...

Houston Methodist Hospital of Texas also found similar viral loads and low Ct values in vaccinated vs unvaccinated infections.

https://www.medrxiv.org/content/10.1101/2021.07.19.21260808v...

Similar finding in Massachusetts:

https://www.cdc.gov/mmwr/volumes/70/wr/mm7031e2.htm

Overall, there's no logical reasoning to not allow tests as a reasonable accommodation and not testing both vaccinated and unvaccinated if the goal is to prevent the spread of COVID.

Also these minute differences in viral loads for maybe 1 to 2 months after inoculation won't be sufficient to justify discrimination based on perceived disability.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#83

Earlier quoted context omitted.

As a counterpoint I wonder how many thousands of lives we could have/would have saved if we reported on delta with the same type of urgency. We don't have the facts yet, and every story I've seen underscores that point. But to just say "we don't know so let's ignore it entirely until we do" seems to minimize the deadliness of the past mutations we've seen.

It is just as irresponsible to say “we don’t have all the facts… but it could render vaccines useless and reinfect everyone and spread like measles and kill like small pox”. Ignoring it is irresponsible. Panicking is irresponsible. This isn’t a difficult or new concept! Each year the flu is a new “variant” and every single year it has the _potential_ to be 1918 all over again. But we don’t close borders and force qua…

I think our top doctor here in bc said it wonderfully. We must anticipate and plan for the worst even as we hope for the best.

It isn't asking for much after what we've been through to go a month with more caution. If we had a 1918 flu, and then another strain worse than that within 2 years, of course we might take some precautions when we find a 3rd strain overtaking the 2nd strain.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#84

> The two doctors had received three doses of the Pfizer/BioNtech vaccine, and so far have shown mild COVID-19 symptoms, the hospital said. The mildness of the symptoms is just as newsworthy as the fact that there are breakthrough infections. It has long been speculated that COVID-19 would evolve into more contagious but less virulent variants. Omicron may be one such variant. If it is, that's probably a good thing.…

It's just as newsworthy in the sense that it's not newsworthy at all. A mild infection in a triple-vaccinated person is the default case. Two such anecdotes tells us basically nothing.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#85

Earlier quoted context omitted.

Yes, you see this as people point out that Gibraltar, a place that is supposedly 100% vaccinated, is experiencing an outbreak of 3000 cases since June. What they leave out is that 4 people have died in Gibraltar of Covid since that outbreak started. In January before vaccines were available, they had an earlier outbreak of 3000 cases. Close to 100 people died during that outbreak. This seems like a very obvious case…

> vaccine skeptic analysis seems to stop at the cases and concludes that the vaccine is ineffective This is not accurate. It's the mandates which most people have problems with, not the vaccine. Mandating something which doesn't prevent transmission under coercion from the government is illogical. The current shots are basically potential severe symptom mitigator - which if you think you would benefit, you should tak…

This is exactly right. Vaccine mandates are the problem, as the US government has done for government employees, and Biden is attempting to do for all employers with over 100 employees. Almost every single person agrees the vaccines are a good thing (now that Trump is out of office) but this specific vaccine goes a step further and does not stop the spread of the virus. Some articles and data extrapolation studies claim it reduces the spread by 5 to even 50 percent in some cases, but it is extremely obvious vaccinated are spreading the disease nearly as much as non vaccinated. Since hospitals never were overwhelmed since COVID began, I don’t even know why the US government is still allowed to make the case that we should be in a state of emergency and under emergency rules passed by the president and governors. All of the lockdowns and emergency orders should have been halted until hospitals were actually overwhelmed, not just projected to be overwhelmed. When it is a real emergency the army will need to set up bases or ships to be hospitals, not just a few doctors working overtime, like they always did already.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#86
post #35

The media really needs to slow their roll, a lot. Two people having breakthrough infections for any variant is not at all unlikely, and this is absolutely not evidence that Omicron is more likely to lead to breakthrough infections. In fact it would only be actually newsworthy if Omicron _didn’t_ break through. And the pointless emotional fact that they are doctors, as if any virus considers ones CV. And the excessive…

Reuters is just reporting an event. Nobody goes to the front page of Reuters to see what stories are important. It’s aggregators like… hacker news… that are fanning the flames.

Journalists should strive for neutrality (good ones try to despite what boulevard tells you, they are on a completely different mission) even if they can never reach it. A case where neutrality fails often is deciding what is newsworthy and what is not.

That said, I don't see that as egregious and of interest because the effectiveness of the vaccine against this mutation is as well. It does not provide answers and the focus on the researchers is questionable, but I don't really see it as a problem or fear mongering.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#87

> The two doctors had received three doses of the Pfizer/BioNtech vaccine, and so far have shown mild COVID-19 symptoms, the hospital said. The mildness of the symptoms is just as newsworthy as the fact that there are breakthrough infections. It has long been speculated that COVID-19 would evolve into more contagious but less virulent variants. Omicron may be one such variant. If it is, that's probably a good thing.…

That seems to be a decent strategy. Virus is endemic and you will catch it at some point. It isn't sure and probably unlikely that immunity against this variant would shield you from the others. Same problem the vaccine has in the end. If there aren't unknown long term effects, the idea doesn't seem to bad. I guess responsible doctors would always advise against this though because it would still be an experiment.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#88

Earlier quoted context omitted.

I am a bit on the fence with Vaccine mandates, I wish they weren't necessary. But I get the key reason for them, which you have missed, is it isn't really about the health choices of the person getting vaccinated. If your vaccination status affected no-one but yourself then I would be strongly against any vaccine mandate. If you are unvaccinated you are more likely to get infected, that is your risk. But, if you do g…

What you are describing falls under "discrimination based on perceived disability" which both Canadian Supreme Court and US Supreme Court have repeatedly frowned upon. The Ontario Human Rights Code includes "any degree of infirmity" in the definition of disability. They also recognize that the definition of disability extends to the actual or perceived possibility that a person may develop a disability in the future.…

Thank you for your informative reply.

You are right, regular (as in, weekly or more frequently) testing should also prove effective at preventing the spread amongst both vaccinated and unvaccinated people.

But, the key there is you would have to trust people to do the right thing, and actually get tested, and isolate if they test positive. I'm not confident that enough people who won't get vaccinated would comply with that.

And you are misusing statistics when you say that a greater growth of cases amongst the vaccinated proves the vaccine doesn't prevent the spread. Everyone knows the vaccine doesn't 100% prevent you catching covid, no surprise there. But it does slow it somewhat, and most crucuially it does greatly reduce your chances of dying or being hospitalized. I'm too lazy to link references, but a quick google would show you plenty of reputable sources with statistics showing you are much safer vaccinated than unvaccinated.

Regarding the greater growth of cases amongst the vaccinated, many, many things explain this. For a start, 76% of Canada's population is vaccinated. So, if the vaccine had no effect then you'd expect 76% of all new cases would be amongst the vaccinated. You stated the actual measure is 53%, so clearly the vaccine is preventing a lot of the spread.

But in the end of the day, setting aside the whole issue of should the vaccine should be mandated or not, disagreeing with the mandate is not a valid reason to not get vaccinated. Just get vaccinated. Once you disregard all the crazy, crazy conspiracy theories about the vaccine "magentizing" your body, or changing your DNA or causing infertility then you are left with a real, but infantesimal risk of a bad reaction to the vaccine. A rational comparison of the risks of getting vaccinated vs the risks of not getting vaccinated cleary shows there is no valid reson to not get vaccinated except a tiny fraction of people who cannot get vaccinated due to valid medical advice.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#89

> The two doctors had received three doses of the Pfizer/BioNtech vaccine, and so far have shown mild COVID-19 symptoms, the hospital said. The mildness of the symptoms is just as newsworthy as the fact that there are breakthrough infections. It has long been speculated that COVID-19 would evolve into more contagious but less virulent variants. Omicron may be one such variant. If it is, that's probably a good thing.…

I think you're reading too much into this. Vaccinated people who get covid _normally_ have mild symptoms.

Re: Two Triple Vaccinated Israeli Doctors Infected with Omicron

#90

Earlier quoted context omitted.

> vaccine skeptic analysis seems to stop at the cases and concludes that the vaccine is ineffective This is not accurate. It's the mandates which most people have problems with, not the vaccine. Mandating something which doesn't prevent transmission under coercion from the government is illogical. The current shots are basically potential severe symptom mitigator - which if you think you would benefit, you should tak…

I am a bit on the fence with Vaccine mandates, I wish they weren't necessary. But I get the key reason for them, which you have missed, is it isn't really about the health choices of the person getting vaccinated. If your vaccination status affected no-one but yourself then I would be strongly against any vaccine mandate. If you are unvaccinated you are more likely to get infected, that is your risk. But, if you do g…

"if you do get infected then you are MUCH more likely to pass the virus onto other people"

No, that isn't the case. Studies have shown there's no difference in infectiousness or viral loads between the vaccinated and unvaccinated, and the original clinical trials didn't even measure infectiousness at all let alone reduce it.

But this hardly matters. Even if there was some small improvement in infectiousness, so what? Vaccines aren't free. They cause collateral damage: some people end up injured, other people end up dead. Given that the virus/viruses are endemic at this point there is no real benefit to reducing infectiousness by some percentage, as vulnerable people will (supposedly) end up getting it anyway no matter what.

Also re: morality. This idea that refusing a vaccine is selfishness is itself enormous selfishness. You are asking healthy young people who are not at risk of COVID to take a risk of getting sick from the vaccine. It seems often that people who push this "vaccines are moral purity" angle cannot really handle this fact and go into denial about it, but there are many such stories out there, and databases filled with reports of such injuries. When you are demanding healthy young people risk sacrificing their own health, just to make you a bit less scared or to give an 80 year old another 8 months of life, it doesn't look like any recognizable morality to me.

Post reply on HN