You'd be surprised at how progressive southern states are. The Texas state motto is literally "Friendship." Now, I don't know much about Texas but I did live in Arizona for a few years. It surprised me more than a bit, as someone who grew up in New York.
Arizona legalized medical marijuana quite early, followed by recreational marijuana. Their medicaid program AHCCCS [1] is extremely comprehensive and even pays for Uber/Lyft to the doctor's office and back. Patients are able to see a great selection of GPs and specialists, and the copay is always $0. The accompanying drug plan is comprehensive, also with a copay of $0. AHCCCS will approve expensive modern drugs like Rozeram (supercharged melatonin analog for sleep) if the sufficient documentation of reasonable need is provided.
Cactuses are protected from destruction by law, and must be transplanted when doing clearing for construction. You may find the idea of being able to own a firearm without a license to be unpalatable but the state largely remains very safe crime-wise (perhaps due to that?)
I miss living in Arizona. It's a beautiful state with very caring folk. I saw almost no homeless folks in Phoenix. Folks there seem to really care about their fellow citizens. Southern hospitality is for sure a thing, take it from a daft boy from Brooklyn!
[1] https://www.azahcccs.gov/