31–40 of 127 posts
Earlier quoted context omitted.
> IIRC, the famous "Good Friday" psilocybin experiment had some people from the control group believe they were not in the control group. I can find a few people right now that believe that Lord of the Rings is a historical account of medieval Europe.
Right but when it comes to questions of placebo, the belief is what matters.
I’m a believer in the potential value but think placebo or blind studies of psychedelics are absurd. You know full well of you’ve eaten an eighth of cubensis. I think to be fair, they should compare psychedelic treatment to other therapies like ECT or a weeklong vacation to Hawaii.
9 weeks of TMS should be tried before ECT. ECT is just one away from a lobotomy in terms of brutality and risk.
Some quick points: > 233 patients Very small, can't generalize results based on such a small number. Doesn't mean the study's trash or anything, but don't jump to any conclusions here - good or bad. > "The trial, which had all patients stopping antidepressants before participating, compared two active doses of COMP360, 25mg and 10mg, against a comparator 1mg dose." - COMP360 was, I assume, their therapeutic psilocybi…
> Very small, can't generalize results based on such a small number. This comes up pretty often, but how many subjects do you need to know getting punched in the face hurts? It's absolutely possible to get statistically significant data from 233 patients, what matters is how the study is designed.
Psilocybin has changed my life. It needs to be available to everyone in the world. Pharmaceutical companies will fuck it up (it's coming - very quickly) so learn to grow your own.
Legality aside, growing and consuming a fungus to me, someone who knows nothing about them outside the grocery store, sounds very dangerous.
Wow, 5% reported suicidal ideation or self harm, in a clinical setting. That’s pretty horrible.
But it changed my attitude towards dying. I think if I had a hopeless disease or was close to dying otherwise I wouldn't fight it but try to die in a peaceful and aware way.
I’m a believer in the potential value but think placebo or blind studies of psychedelics are absurd. You know full well of you’ve eaten an eighth of cubensis. I think to be fair, they should compare psychedelic treatment to other therapies like ECT or a weeklong vacation to Hawaii.
I’m a believer in the potential value but think placebo or blind studies of psychedelics are absurd. You know full well of you’ve eaten an eighth of cubensis. I think to be fair, they should compare psychedelic treatment to other therapies like ECT or a weeklong vacation to Hawaii.
One way to do this — and I don’t know why it isn’t done — is to use a general anesthetic and then administer drug/placebo and record effects.
I am pretty prone to depression and I definitely feel it lifting for a while after microdosing or taking a larger dose. Unfortunately I have never experienced a life changing trip that solved all problems as you may want to believe when you read some of the latest articles about the miracle of psilocybin and other psychedelics. Same for Ayahuasca. It seems to help a lot of people but for me it was more just a very in…
I am pretty prone to depression and I definitely feel it lifting for a while after microdosing or taking a larger dose. Unfortunately I have never experienced a life changing trip that solved all problems as you may want to believe when you read some of the latest articles about the miracle of psilocybin and other psychedelics. Same for Ayahuasca. It seems to help a lot of people but for me it was more just a very in…
I’m a believer in the potential value but think placebo or blind studies of psychedelics are absurd. You know full well of you’ve eaten an eighth of cubensis. I think to be fair, they should compare psychedelic treatment to other therapies like ECT or a weeklong vacation to Hawaii.
I'd love to poo-poo this because I believe in (and do) CBT and have a continuing high level engagement with somebody which is strongly anti-drug: the SSRI are a weapon for a problem which are being over-used. Its classic hammer/nail analogy stuff.
There was interesting, good science being done on these drugs before the "war on dope" took everything offline.
Consider the work on its effect on timor mortis. If we can ease people's passage into an inevitable end, Isn't that net-beneficial overall?