Live data from Hacker News

Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

941–950 of 1001 posts

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#941

Earlier quoted context omitted.

The first three days of symptoms for an anti-vaxxer are obviously just a flu, because covid is fake. It's not covid until they're hooked up to a machine...

There are many who won't even get a test now, to check if it's COVID. They ride it out, and won't know if they just had a flu, cold, or COVID. And thus it seems we've currently plateaued in case counts in the US :(

Check out Reddit.com/r/hermancainaward for this exactly

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#942
post #70

Earlier quoted context omitted.

If the cost is low enough and the side effects are mild enough it could work. People would take it before a test is positive so would end up taking it when they didn’t really need it. It’s similar to the antivirals for flu where you need to take it early on so it becomes habit to test early and start early. Home labs will help with this too. Where someone could take a test, get a prescription and pickup within a few…

A useful comparison. I have never taken Tamiflu because I know I’d need to haul my weak, shivering, flu-infected self through public to see a doctor to get the Rx, go to the pharmacy… all for the personally-uncertain benefit of Tamiflu. Nowadays, this should be easier with so many virtual appointment options and delivery services. It should be, but is it? There should be an app that does all of it for you. 1. Scan yo…

There are a couple issues off the bat.

1. You're minimizing the 2 hardest parts of doing anything medical, which is the insurance billing and state licensing requirements. The state may consider you a medical services provider even if all you do is pair people with already-certified medical professionals.

2. "That day, some delivery service will bring you the Rx." This sounds illegal or heavily licensed/regulated. It's a drug addict's dream because it's so easy to maintain multiple identities. You probably get a random doctor, so the doctor won't notice it's you with a different name. And then they even send a driver to pick up the prescription, so the pharmacy won't notice that it's you with a different name.

The pharmacy would also likely need to be in on it. I.e. in Texas, pharmacies that deliver are required to include any information that would have been given orally as a written document with the prescription. If the pharmacy doesn't know it's being delivered, they won't know to include those.

If you wanted to partner with someone, it would be CVS or Walgreens, though. They already have licensed pharmacies everywhere, and handling the pharmacy requirements are going to be the hard part. I believe they also own a lot of those tiny clinic chains that are inside grocery stores, and this would give them a way to fill in any downtime in the nurses' schedules, as well as to let them soak up excess demand in one area with slack in another.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#943
post #846

Earlier quoted context omitted.

Advertising includes drug samples given to doctors, which many/most of them give to patients who can't afford said drugs. How many of them are you willing to cut off?

All of them. Having some drugs laying around and handing them out as medication is wildly irresponsible

That's not how it works. The doctor prescribes the drug and gives the patient the free sample. What, did you think they were in a "take one" candy jar?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#944
post #445

Earlier quoted context omitted.

I'd say that this will appeal to people who are covid vaccine skeptical. If you're skeptical of the mRNA vaccines, you'd probably be in favor of this treatment than the vaccines.

I had one vaccine dose with severe issues. So maybe I'm skeptical, I won't get a second or third dose. Most people in this camp will just use ivermectin. Including myself, it works and is safe.

There is no evidence ivermectin works against COVID. There is still one large study running, I think, that might show a small effect, but definitely not a big effect.

Sorry you had a severe issue with your vaccine.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#945

Earlier quoted context omitted.

The vaccine neither outright prevents spread nor severe symptoms, but it dramatically reduces the probability of both.

It increased the risk of spread by increasing viral load up to 157 times. This fact is not up for debate.

Do you have a reference for this?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#946
post #854

Rejoice, for pfizermectin is now upon us. Did they at least test the study participants for natural immunity ahead of time? In related news, Merck's molnupiravir has been approved in the UK as well.

Why would that matter? Treatment is randomly assigned.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#947
post #891

Earlier quoted context omitted.

The Latest article in BMJ about the failures in scientific integrity in the pfizer trials are a likely consequence of your last paragraph I would guess.

Can you provide a link to that?

https://www.bmj.com/content/375/bmj.n2635

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#948
post #854

Rejoice, for pfizermectin is now upon us. Did they at least test the study participants for natural immunity ahead of time? In related news, Merck's molnupiravir has been approved in the UK as well.

Why would that matter? Treatment is randomly assigned.

Because you can't trust Pfizer, unfortunately. Here's how they run their "studies" nowadays: https://www.bmj.com/content/375/bmj.n2635. This is just one lab, nobody has come forward (yet) about others, and given that the whistleblower has been fired right away, chances of other whistleblowers coming forward are pretty low. Be that as it may, I regard whatever they say about safety or efficacy of their products the same way I did in 2019 - with extreme suspicion.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#949
post #846

Earlier quoted context omitted.

Pharma companies in the US spend about twice as much on advertising as they do on R&D [1]. Recent data compiled by the House Oversight Committee shows the biggest pharma companies spent $56 billion more on stock buybacks and dividends than they did on R&D over the past five years [2]. Very little of the ridiculous prices that US citizens pay for medicine (directly or via insurance) actually goes towards R&D. [1] http…

Advertising includes drug samples given to doctors, which many/most of them give to patients who can't afford said drugs. How many of them are you willing to cut off?

Free samples over R&D? In what world does that sound... sound?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#950
post #948

Earlier quoted context omitted.

Why would that matter? Treatment is randomly assigned.

Because you can't trust Pfizer, unfortunately. Here's how they run their "studies" nowadays: https://www.bmj.com/content/375/bmj.n2635 . This is just one lab, nobody has come forward (yet) about others, and given that the whistleblower has been fired right away, chances of other whistleblowers coming forward are pretty low. Be that as it may, I regard whatever they say about safety or efficacy of their products the s…

Then your criticism makes even less sense. If they tested for natural immunity, they could put the people who have natural immunity in the vaccine group.
Post reply on HN