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Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

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Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#771

Post by ricardobeat »

greeneggs wrote: post #735
semi-extrinsic wrote: post #702

Earlier quoted context omitted.

Pharma companies in the US spend about twice as much on advertising as they do on R&D [1]. Recent data compiled by the House Oversight Committee shows the biggest pharma companies spent $56 billion more on stock buybacks and dividends than they did on R&D over the past five years [2]. Very little of the ridiculous prices that US citizens pay for medicine (directly or via insurance) actually goes towards R&D. [1] http…

Your first link is from 2008, and analyzes data from 2004. I don't see how this proves anything, or even suggests much, about the industry today. Your second link shows that the pharma companies spend almost as much on R&D as on stock dividends and buybacks. Is there any other industry that spends as much on R&D? Apple, for instance, seems to be spending ~6x as much on stock buybacks and dividends as on R&D (approxim…

This is not a dick measuring contest. The comment was challenging the notion that pharmaceuticals companies spending the majority of their cash on advertising and stock buybacks is a desired outcome. The specific numbers, especially across industries, are meaningless.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#772

Post by epakai »

dboreham wrote: post #715
jdhn wrote: post #445

Earlier quoted context omitted.

I'd say that this will appeal to people who are covid vaccine skeptical. If you're skeptical of the mRNA vaccines, you'd probably be in favor of this treatment than the vaccines.

Because _absolutely_ _anything_ is less dangerous than mRNA.

mRNA has potential to be dangerous. There is nothing inherently dangerous in what our bodies already use as building instructions, nor is there evidence to suggest current mRNA vaccines cause any of these theoretical issues.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#773

Post by ldehaan »

foolinaround wrote: post #334
shusaku wrote: post #19

I think it’s hard to overstate what a big deal this is for science. This is a completely novel molecule that appears effective as an antiviral. This would a huge achievement for the field of drug design, and will hopefully lead to all kinds of great medicine.

> completely novel molecule Can someone please ELI5 what makes this unique from others?

They can copyright it and make tons of money off of it is what it means. All of the other things that already work can't make them insane profits so, bought and paid for the news that you are fed tells you this is one of few valid ways to fight a virus you can dodge by staying in the sun for an hour each day and exercising your body.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#774

Post by nijave »

orra wrote: post #717
jdhn wrote: post #445

Earlier quoted context omitted.

I'd say that this will appeal to people who are covid vaccine skeptical. If you're skeptical of the mRNA vaccines, you'd probably be in favor of this treatment than the vaccines.

I'm not so certain. People who for whatever irrational reason don't want an mRNA vaccine can take a viral vector vaccine. Yet they don't.

Monoclonal antibodies get less pushback https://www.nytimes.com/2021/09/18/health/covid-antibody-reg...

I think there's also some "it won't happen to me" mentality that quickly disappears once it does (which is far too late for a vaccine)

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#775

Post by oezi »

docmars wrote: post #759
oezi wrote: post #749

Earlier quoted context omitted.

Well the authors could start by giving their names instead of running an anonymous page online. Then they could actually use a methodology that makes sense.

And what of the methodologies presented in the individual studies? Are they not sufficient? Who are you, or anyone, to assume the curator / scientist / reporter who put this together is acting with negative intent when it presents a positive outlook for the use of other treatments that have manifested in good outcomes and healing? Don't get me wrong, it's good to be skeptical, just not selectively.

Don't get me wrong Doc. Neither you nor I nor a random dude with a web-site has the capacity to make statements that might lead people to make medical decisions. Leave that to doctors and governments please.

It is good to be skeptical, but also important to trust the right people.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#776

Post by ldehaan »

jjwiseman wrote: post #767
zapdrive wrote: post #600

Earlier quoted context omitted.

Being in BC, Canada sucks. I went in to an Apple store to buy the fully loaded MacBook M1 max, with 6000 dollars in my hand (literally). And was told to leave the store because my mask didn't cover my nose. I'm buying a Razer 15 now. And I'm fully vaccinated. Not because I was scared of getting sick (i already contacted COVID twice before the vaccine, including the Delta variant), but because I was shamed into gettin…

If you don't understand by now that vaccines significantly reduce transmission, you just need to google "do covid vaccines reduce transmission". The top results are links to the CDC, Nature, New Scientist, the New England Journal of Medicine, The Lancet, and more, all saying that vaccines significantly reduce transmission. Vaccines significantly reduce transmission, so if someone is telling you they don't, you need t…

You must be young.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#778

Post by somewhereoutth »

inglor_cz wrote: post #765
thehappypm wrote: post #680

Earlier quoted context omitted.

I doubt we’ll see molnupiravir getting approved in this context now. I think the mechanism just has too much risk.

Already approved in the UK: https://www.bbc.com/news/health-59163899

Unfortunately in the UK there has been political pressure to do absolutely anything (no matter how questionable - e.g challenge trials) that isn't imposing even the slightest restriction.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#779

Post by inglor_cz »

somewhereoutth wrote: post #778
inglor_cz wrote: post #765

Earlier quoted context omitted.

Already approved in the UK: https://www.bbc.com/news/health-59163899

Unfortunately in the UK there has been political pressure to do absolutely anything (no matter how questionable - e.g challenge trials) that isn't imposing even the slightest restriction.

Rolling review for the EU is underway. Let's wait how it turns out.

https://www.ema.europa.eu/en/news/covid-19-ema-starts-rollin...

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