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Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

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Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#591

Post by zapdrive »

TacticalCoder wrote: post #583

So no we have the Pfizer vaccine (which I got) who cuts the risk of both catching the virus and the risk of severe complication by a lot (forgot the number but it's big) and in addition to that we now have Pfizer oral medication that can be given to positive cases and which reduces both hospitalization and death risk by 85%. When can life go back to normal?

Lol, you think life will go back to normal? That's cute. Just like how airport security went back to normal a few years after 9/11? The powers of the world are not going to let this pandemic go to waste. There's a lot of money to be made and a lot of freedoms to be trampled.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#592

Post by fknorangesite »

president wrote: post #504
fknorangesite wrote: post #480

Earlier quoted context omitted.

> the common anti vax sentiments I hear on this web site (ugh). Seeing this stuff so prevalent on HN really disappointed me.

Try to understand why this viewpoint exists. We are all logical people. The difference is in the trust of public media and government. Both sides of the argument are mostly right in what they believe given the information they are consuming. My suggestion - read sources from both sides before deciding that anyone slightly against Covid hysteria is misinformed and is an anti-vaxxer. Second suggestion, anti-vaxxer is a…

> My suggestion - read sources from both sides

I assure you I have; only one of those sides has any intellectual merit.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#593

Post by xxpor »

subsubzero wrote: post #561
pie42000 wrote: post #491

Earlier quoted context omitted.

This is what being an engineer during WW2 must have been like. Near infinite money and resources, but very tough deadlines

agree, The manhattan project alone was 1% of the US GDP during its most expensive year, that would equate to $230 Billion in today's dollars.

Along these lines, for anyone who hasn't heard of it:

At the Trinity test, there was a containment unit called Jumbo:

https://www.atomicheritage.org/history/jumbo

Basically, if Trinity fizzled, they wanted to be able to recover the billion dollar plutonium core.

It didn't actually end up being used, and so it was ordered destroyed. But the thing was so tough that they essentially couldn't blow it up. Normal bombs just weren't powerful enough. So now it's just sitting there at the site.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#594

Post by y-c-o-m-b »

ryandrake wrote: post #524
VRay wrote: post #385

Earlier quoted context omitted.

It’s pretty amazing how stupid and shortsighted people are. We’re so good at overlooking the horrible situation we’re in and focusing on other things that are completely irrelevant I used to think that one of the worst things in the USA was that 100 people per day die in preventable car accidents, but now we’re getting 10x that from a virus and people pretend that it isn’t happening

The last two years have convinced me: When the Zombie Apocalypse comes, zombies are biting and killing people in the streets, and neighborhoods are burning down, 50% of the country (world?) will whistle and just continue to go about their day, shopping, going out to eat, sending their kids to school, and looking down at all those hysterical alarmists bunkering up trying to defend themselves from the hoard. "Governmen…

Haha I've had this conversation with my wife as well. We've basically been under house arrest since early February 2020 (yes we quarantined even before there was a quarantine) and taking very conservative measures since, always 1 step ahead of the CDC the whole time with double masking and still masking when mandates were lifted here in Oregon because we knew there would be an immediate re-surge.

I told my wife I used to think we'd be one of the first to die in the Zombie Apocalypse because her and my kids are all high-anxiety people that typically crumble with too much psychological pressure. Yet covid has shown me we'd actually be one of the longest survivors given our resilience so far and how we haven't caved into the pressures of society itching to get back to normal. My dad - a self-proclaimed "survivalist" and doomsday prepper didn't make it even two months before he gave up on quarantining. He said the psychological stress was too much, he couldn't handle it lol

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#595

Post by rangoon626 »

HWR_14 wrote: post #413
tut-urut-utut wrote: post #366

Earlier quoted context omitted.

"Please don't talk about risk with so much at stake. Just push that code you wrote this morning to our mission-critical production system." "We can do proper code review, unit testing, integration testing and full test cycle later on, when the pressure fades away." We engineers all understand the risk of pushing untested code to production, but when it comes to medicine and other fields, we forget everything and rush…

This already went through Phase III trials. It's closer in analogy to having the entire QA team on standby at their desks to do a full test as soon as you submit a PR at 1:38am for a feature that has to go live ASAP.

Lol did you not see the revelations about what was going on inside of Ventavia, the contractor that did the trial research for pfizer?

They broke all sorts of protocols, covered it up, had it reported to the FDA, who in turn just sat on it.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#596

Post by rangoon626 »

bun_at_work wrote: post #319
toyg wrote: post #109

Earlier quoted context omitted.

Yeah it's not really researchers that I'm worried about, it's their bosses.

Can you provide an example of a treatment people would like that 'big pharma' wouldn't produce because they couldn't make a profit on it? This is such a ridiculous argument, IMO. As a thought experiment consider something like cancer treatment. If some pharma company researcher found a way to 100% prevent or reverse cancer, why would the company hide that? In the best case, they could make a ton of money from it by s…

The companies who make today's lengthy and expensive cancer treatments, are also making the mass-marketed personal care products that have carcinogens inside of them.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#597

Post by dougmwne »

freddealmeida wrote: post #484

I don't trust Pfizer in any case. But interesting at least. I think it needs far more study before this is simply introduced into the wild. But what do I know. We have survived for 2m years without this. I'm sure we can be fine without it.

Sure, we survived as a species, but certainly not as individuals. We see plenty of evidence of genetic bottlenecks where the human population was reduced to small numbers, quite possibly due to disease. Just within the historical period, there are legions of plagues with extremely high mortality rates, including nearly the entire native population of North America after contact with Europeans. And let’s not forget antibiotics and near every lifesaving piece of medical knowledge we have developed over the last few thousand years. It’s your choice to refuse medical care, but don’t assume the rest of us want to go back to the caves and the hunt. Rapid drug discovery is an extremely powerful medical technology and I 100% welcome it for this disease and all futures ones.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#598

Post by spaetzleesser »

thehappypm wrote: post #390

It’s crazy that money is such a huge incentive. Knowing that a cure for Covid is a potentially $100B market means you throw the kitchen sink at it. Imagine being this lab. Do you think they ever had trouble hiring an assistant? Buying new equipment? Getting bonuses? This environment must be fantastically different from the typical meat grinder of bio R&D.

It’s also a boom and bust business. Once COVID has gone away I bet funding will dry up and a lot of these people will have trouble finding work.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#599

Post by NullPrefix »

VRay wrote: post #358
40four wrote: post #301

Earlier quoted context omitted.

I live in South Carolina as well, and I can confirm (I think you meant 2021 not 2020?). Most people in my city have been going about life as usual since ~ May if this year. Almost nobody wears masks. Everything is open. And guess what? We’re all good! The sky isn’t falling. Hospitals aren’t being overrun. Life is good, and I can remember the last time I worried or had anxiety about Covid. There seems to be a group of…

https://covid19.healthdata.org/united-states-of-america/sout... Doesn’t look too bad so far as the USA goes, although if legal gun owners or Mexican cartel members were out there killing 40 people a day, you’d be screaming bloody murder about it

How many people are dying because of obesity? There's an epidemic going on and I hear no bloody murder screams near any McDonald's

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#600

Post by zapdrive »

danielvf wrote: post #195
wincy wrote: post #169

Earlier quoted context omitted.

I live in Kansas and have basically forgotten COVID is a thing. The people who wanted to get vaccinated like me have and those who haven’t, haven’t. Nobody asks about it and no businesses have any sort of mask requirements. Half of the people at the grocery store wear masks and the other half don’t. Everyone seems to be getting along. Next door in Kansas City Missouri I stopped at a gas station and an employee was sh…

Pretty much the same story in South Carolina. Outside retail workers, mask usage in my hyper local area is about 2%. Life has been basically completely normal since June 2020.

Being in BC, Canada sucks. I went in to an Apple store to buy the fully loaded MacBook M1 max, with 6000 dollars in my hand (literally). And was told to leave the store because my mask didn't cover my nose. I'm buying a Razer 15 now.

And I'm fully vaccinated. Not because I was scared of getting sick (i already contacted COVID twice before the vaccine, including the Delta variant), but because I was shamed into getting it (think about the immunocompromised!!!). And now I'm being told that vaccine doesn't prevent transmission? So now I'm being shamed into wearing a mask.

And now the govt is trying to bully the 10% teachers who are not vaccinated. They might lose their jobs if they don't get the shots. Think about the children!!! But wait a minute, the vaccines don't prevent transmission. So even if the teachers get vaccinated, how is it going to help the children?

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