Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

Post reply on HN
Print view View original

521–530 of 1001 posts

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#521

Post by colordrops »

jasonpeacock wrote: post #213
colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

When hospitalization rates are down. In many metro areas the ICU are still full of un-vaccinated COVID patients, which means people with normal emergencies can't get a bed. Thus, COVID precautions are necessary to reduce the rate of infection to levels that do not overwhelm the healthcare system. And all those areas that have "returned to normal" are sending their COVID patients to regions that are still masking beca…

Aren't the unvaccinated people in ICUs already not following COVID mandates? In areas of Southern California (e.g. Temecula) with low vaccination rates, there are virtually no restrictions. Why restrict a compliant populace that is already mostly vaccinated?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#522

Post by kgin »

School-Cotton wrote: post #138
colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

It seems like we are experiencing a very slow and gradual offramp from the restrictions, rather than something that will have a clearly defined endpoint. 2021 is already "mostly normal", for me. I hope sometime in 2022 we will be back to "100% normal", but I'm not confident.

Masks became a regular fixture in Asia after original SARS. Not by regulation, but they just became an ordinary item used by people to avoid getting sick or avoid getting others sick.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#523

Post by colordrops »

striking wrote: post #354
horns4lyfe wrote: post #335

Earlier quoted context omitted.

Can you point me to a mandate anywhere with some kind of hospitalization rate cutoff? Because everywhere where there are still mask mandates, they seem to be nebulous things that will just last until it’s no longer politically popular. Oregon for example set an arbitrary date, which of course makes no sense.

Bay area (note that there are additional criteria): https://www.sfgate.com/coronavirus/article/Bay-Area-mask-man...

Does LA County have anything like this? I haven't been able to find it.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#524

Post by ryandrake »

VRay wrote: post #385
Loughla wrote: post #234

Earlier quoted context omitted.

>And all those areas that have "returned to normal" are sending their COVID patients to regions that are still masking because they've exhausted their local ICU capacity. This has been my experience as well. My state is pretty strict overall, but my area of my state is not. Our hospital has been operating at capacity for 6 months or so, but nobody is talking about it. Because we can just ship to where they have stric…

It’s pretty amazing how stupid and shortsighted people are. We’re so good at overlooking the horrible situation we’re in and focusing on other things that are completely irrelevant I used to think that one of the worst things in the USA was that 100 people per day die in preventable car accidents, but now we’re getting 10x that from a virus and people pretend that it isn’t happening

The last two years have convinced me: When the Zombie Apocalypse comes, zombies are biting and killing people in the streets, and neighborhoods are burning down, 50% of the country (world?) will whistle and just continue to go about their day, shopping, going out to eat, sending their kids to school, and looking down at all those hysterical alarmists bunkering up trying to defend themselves from the hoard. "Government, don't force me to change my life! I have the freedom to pretend everything is normal!"

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#525

Post by decebalus1 »

thr0w72594 wrote: post #268
colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

Subramanian Kumar 2021 [1] found that there is no correlation between vaccination rates and new case rates on a country-wide level, or a county-wide level in the United States. This tracks with Dr. Vanden Bossche's assessment [2] from March of this year that mass vaccination with prophylactic vaccines will actually prolong and worsen the pandemic due to shedding of infectious variants. [1] https://www.ncbi.nlm.nih.go…

Stop spreading misinformation. The 'study' is in itself a case study about shitty studies. Also check who Akhil Kumar is and what are his credentials.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#526

Post by HWR_14 »

blackbear_ wrote: post #123
matsemann wrote: post #106

Earlier quoted context omitted.

If the consequence of not taking it is death, I think people would run to the front of the queue, though.

Soo, kinda like for a vaccine? (And to clarify what I am saying, even though the vaccine does prevent death, there is still considerable push back. Not sure why it will be different for this drug)

There are a lot of hospital bed requests for the vaccine(1) from people who thought COVID wasn't a big deal. I'm fairly sure they'll take this drug once they experience the alternative.

1) Obviously, it's too late then. So it's only the most ignorant of people who changed their minds we have anecdotes of.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#527

Post by standardUser »

jaywalk wrote: post #344
pezzana wrote: post #327

Earlier quoted context omitted.

No. There's a big difference between drugs and vaccines. The drug doesn't generally illicit an immune response, but the vaccine is designed to do exactly that.

But by definition, anyone taking this drug is already infected. So their immune system has already been exposed to the virus.

With antibiotics, it is possible to kill an infection without developing a full immune response, leaving the person susceptible to reinfection. Even if that infection is symptomatic and has been going on for days, the immune response still may not be robust enough before the antibiotics kill off the infection. Not sure if that also occurs with anti-virals.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#528

Post by colordrops »

zionic wrote: post #350
jasonpeacock wrote: post #213

Earlier quoted context omitted.

When hospitalization rates are down. In many metro areas the ICU are still full of un-vaccinated COVID patients, which means people with normal emergencies can't get a bed. Thus, COVID precautions are necessary to reduce the rate of infection to levels that do not overwhelm the healthcare system. And all those areas that have "returned to normal" are sending their COVID patients to regions that are still masking beca…

The medical cartel has had 2 years to adapt at this point. How have they failed to scale capacity despite charging record prices?

If they scale then the politicians won't have an excuse to maintain their mandates. They were able to get navy ships with hundreds of beds scaled up in weeks at the start of the pandemic. The cost to society of the mandates is certainly more that it would cost to scale ICUs.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#530

Post by themitigating »

ryanobjc wrote: post #421
thehappypm wrote: post #390

It’s crazy that money is such a huge incentive. Knowing that a cure for Covid is a potentially $100B market means you throw the kitchen sink at it. Imagine being this lab. Do you think they ever had trouble hiring an assistant? Buying new equipment? Getting bonuses? This environment must be fantastically different from the typical meat grinder of bio R&D.

Therefore how can you trust this drug? Follow the money! It’s just big science trying to propagate a pandemic to make more money! If this sounds insane, we’ll ok just reflecting the common anti vax sentiments I hear on this web site (ugh).

Every business exists to make money, the same with most people.
Post reply on HN