Wouldn't reducing the high that users get from the same dose lead to addicts taking more, and eventually overdosing? A kind of reverse scenario where someone who has been clean for a while takes way too much and ODs anyway.
New drug to treat meth addiction receives major NIH grant
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Re: New drug to treat meth addiction receives major NIH grant
#12Addiction is complicated. There's the drug and then there's the (mental) illness and/or pain the (eventual) addict is trying to cure. And finally, there's context. That is, being in an environment where drugs are available makes saying no difficult.
Dealing with the drug part of the equation is certainly a positive. But there's still the individual and her/his demons, as well as the environmental factors. Without "cures" for the latter two, the former (drugs) isn't going to get as far as conventional wisdom likely expects.
Re: New drug to treat meth addiction receives major NIH grant
#13What’s the point? Meth isn’t a huge European issue is it? They’re usually dealing with impure amphetamine pastes. They already can block it with antipsychotics which block dopamine. Since addiction to stimulants is much faster to recover from, they can even just induce sleep for 3 days and all physical withdrawal will be gone and the dopamine receptors will recover. Is the monoclonal antibodies treatment just an arti…
I've watched hundreds of meth/"meth" addicts get clean over the past couple of decades. And though the withdrawal period may be short, the amount of time after physical withdrawal until they can exhibit any kind of cohesive and structured thought is generally about 12 months. We call it the "Spin Cycle" in the circles I frequent.