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New drug to treat meth addiction receives major NIH grant

pharmamanufacturing.com

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Re: New drug to treat meth addiction receives major NIH grant

#3

Post by tyingq »

"reduce the euphoric rush associated with the drug and help prevent overdose"

Doesn't mention reducing cravings. I wonder how effective it would be then. Things like naltrexone and buprenorphine both reduce the euphoric rush and reduce cravings for opiates. And even with both effects, those don't have phenomenal success rates.

Re: New drug to treat meth addiction receives major NIH grant

#6

Post by pvarangot »

latchkey wrote: post #4

This was an interesting meth related article that came up on HN the other day: https://dynomight.net/p2p-meth/ The chemical structure has changed over time and that has made people more 'crazy'. I really hope that research like this works to help people.

That article is saying that's there's just more and cheaper meth, with the same chemical structure as always but less of the non-psychoactive enantiomer. That the "chemical structure changed" was in another bullshit article that popped up here a few days before and it's just not what's going on with the meth supply chain.

Re: New drug to treat meth addiction receives major NIH grant

#7

Post by latchkey »

pvarangot wrote: post #6
latchkey wrote: post #4

This was an interesting meth related article that came up on HN the other day: https://dynomight.net/p2p-meth/ The chemical structure has changed over time and that has made people more 'crazy'. I really hope that research like this works to help people.

That article is saying that's there's just more and cheaper meth, with the same chemical structure as always but less of the non-psychoactive enantiomer. That the "chemical structure changed" was in another bullshit article that popped up here a few days before and it's just not what's going on with the meth supply chain.

Cool, thanks for the info!

> and it's just not what's going on with the meth supply chain.

I'm curious, can you elaborate?

Re: New drug to treat meth addiction receives major NIH grant

#8

Post by woah »

latchkey wrote: post #4

This was an interesting meth related article that came up on HN the other day: https://dynomight.net/p2p-meth/ The chemical structure has changed over time and that has made people more 'crazy'. I really hope that research like this works to help people.

The article you link is debunking the "new meth" theory being pushed by https://www.theatlantic.com/magazine/archive/2021/11/the-new...

And probably rightfully so. The Atlantic article did not have any information about anyone having done any research uncovering a "new type of meth" and was basing that conclusion only on the reporter's leading questions to uninformed people.

There seems to be a tendency for reporters to make a fuss about supposedly new, more dangerous versions of common drugs, like the "skunk" hysteria of the 2000's. Probably gets more clicks than just writing about how drug addiction is still a problem just as it has been for thousands of years.

Re: New drug to treat meth addiction receives major NIH grant

#9

Post by GhettoComputers »

What’s the point? Meth isn’t a huge European issue is it? They’re usually dealing with impure amphetamine pastes.

They already can block it with antipsychotics which block dopamine. Since addiction to stimulants is much faster to recover from, they can even just induce sleep for 3 days and all physical withdrawal will be gone and the dopamine receptors will recover.

Is the monoclonal antibodies treatment just an artifact of the COVID one like how mRNA treatments will probably also be in the pipeline from research?

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