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CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

mdpi.com

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Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#71

Post by josh_today »

GhettoComputers wrote: post #66
josh_today wrote: post #65

Earlier quoted context omitted.

You have no way of proving mRNA is safe long term. People need to stop with that blanket statement.

mRNA is naturally occurring and all the issues are from the adjuvants. It’s like complaining about amino acids, plasma or cells. The vaccine efficiency rate drops by about half in 5 months, it’s not a sturdy permanence. If you are so worried about mRNA, why are you not concerned about its natural occurance in your body since mRNA isn't provent to be safe?

No way of proving mRNA vaccines are safe long term

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#72

Post by GhettoComputers »

josh_today wrote: post #71
GhettoComputers wrote: post #66

Earlier quoted context omitted.

mRNA is naturally occurring and all the issues are from the adjuvants. It’s like complaining about amino acids, plasma or cells. The vaccine efficiency rate drops by about half in 5 months, it’s not a sturdy permanence. If you are so worried about mRNA, why are you not concerned about its natural occurance in your body since mRNA isn't provent to be safe?

No way of proving mRNA vaccines are safe long term

Just like how your platlets, ribosomes, mitocondria and other natural classes of biologicals that naturally occur inside you are not proven to be safe.

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#73

Post by m0zg »

GhettoComputers wrote: post #72
josh_today wrote: post #71

Earlier quoted context omitted.

No way of proving mRNA vaccines are safe long term

Just like how your platlets, ribosomes, mitocondria and other natural classes of biologicals that naturally occur inside you are not proven to be safe.

And dihydrogen monoxide is often used as engine coolant. Let's not get ridiculous here. The concerns are reasonable: this is the first time this technology has been deployed at scale. Using it is a risk, and not using it is also a risk (COVID is no picnic either), and one must look at the data before making decisions, if one is able to make data-driven decisions at all.

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#74

Post by TravisDick »

revolvingocelot wrote: post #21
TravisDick wrote: post #2

I didn't read the article, but my very basic understanding of mRNA vaccines is that they cause your own cells to produce the spike protein so that your immune system can learn to attack it without actually having the virus present. Does this finding imply that the vaccine would also inhibit DNA damage repair? Or is it more like, in combination with the virus, the spike protein inhibits DNA repair?

edit: this journal might not be worth paying attention to https://en.wikipedia.org/wiki/MDPI#Controversies >Does this finding imply that the vaccine would also inhibit DNA damage repair? Well, yes , but consider the context. If you read the article, and it's almost beyond belief that I have to recommend that you read the article in order to discuss it -- indeed, the information that might assuage your fears is in the…

Thanks for the response! And absolutely a fair point about reading the article. I wasn't really trying to look for ways that the vaccines do damage, given that the risks of covid seem to clearly be higher. Just wanted to check if I understood the implication correctly. Thanks again!

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#75

Post by GhettoComputers »

m0zg wrote: post #73
GhettoComputers wrote: post #72

Earlier quoted context omitted.

Just like how your platlets, ribosomes, mitocondria and other natural classes of biologicals that naturally occur inside you are not proven to be safe.

And dihydrogen monoxide is often used as engine coolant. Let's not get ridiculous here. The concerns are reasonable: this is the first time this technology has been deployed at scale. Using it is a risk, and not using it is also a risk (COVID is no picnic either), and one must look at the data before making decisions, if one is able to make data-driven decisions at all.

mRNA as a class is safe. That is not a debate. If he’s worried about the current mRNA vaccine as a single entity he can say that or it’s effects. But he stated there is no evidence mRNA is safe. That is ridiculous as being afraid of your own shadows and that concern is not reasonable. He later says mRNA vaccines aren’t proven to be safe, which is what my post states due to externalities. But he doesn’t know what he’s talking about and can’t state any clear concerns because he’s not done any research but thinks his uninformed opinion based on ignorance without any evidence for his skeptical blanket statements is merited.

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#77

Post by GhettoComputers »

m0zg wrote: post #70
mc32 wrote: post #58

Earlier quoted context omitted.

I think it makes sense to vaccinate vulnerable populations. Elderly, and those with comorbidities, however, pre-adolescents I don’t think need it, especially as we don’t know long term effects on the young. For old folks, the reward is well worth any risk. For youngsters given their risk profile, I’m not so sure as we lack information given the trials on youngsters were short and we don’t have long term data.

Exactly my thinking as well. Mandates (and other forms of "encouragement") should be by BMI, age, and comorbidities. I'd be covered by a mandate myself, if one existed: high BMI, (treated) high blood pressure, haven't had COVID (yet, that I know of). That's why I chose to vaccinate myself and that's also why my wife chose to vaccinate. I don't have to do it, I'm self employed, I've done it voluntarily. Moreover, if i…

The issue is that the most vulnerable elderly people get terrible effects or die from the immune response. They need to be healthy enough to receive the vaccine, if they’re old and sickly it’s better to vaccinate everyone around them and continue to keep their immune response up.

The second most vulnerable elderly people are prime candidates for vaccination though. They’re not as old, more healthy and less likely to have complications from the vaccine. It can be very dangerous for very old or sickly people and those are the people that others vaccinate for so they don’t get it themselves.

The heart problems aren’t common but I didn’t get vaccinated myself, I was waiting for the novavax which they kept delaying. Hopefully by next year it’ll be released, I’ll be first in line since it doesn’t have the same issues that concern me about mRNA or adenovirus.

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#78

Post by m0zg »

GhettoComputers wrote: post #75
m0zg wrote: post #73

Earlier quoted context omitted.

And dihydrogen monoxide is often used as engine coolant. Let's not get ridiculous here. The concerns are reasonable: this is the first time this technology has been deployed at scale. Using it is a risk, and not using it is also a risk (COVID is no picnic either), and one must look at the data before making decisions, if one is able to make data-driven decisions at all.

mRNA as a class is safe. That is not a debate. If he’s worried about the current mRNA vaccine as a single entity he can say that or it’s effects. But he stated there is no evidence mRNA is safe. That is ridiculous as being afraid of your own shadows and that concern is not reasonable. He later says mRNA vaccines aren’t proven to be safe, which is what my post states due to externalities. But he doesn’t know what he’s…

> mRNA as a class is safe.

That's like saying "chemicals are safe". I'm pretty sure the same folks who created the Moderna vaccine could just as well cook up a doomsday military grade pathogen using the same equipment and technology, over approximately the same period of time (a weekend).

I'm not saying vax is not safe. Its safety record, while not perfect, is relatively well understood in adults (but wasn't at the outset). I'm merely saying it's a risk, that should be weighed against the benefits, which (IMO) significantly outweigh the risks for me personally, but not necessarily for someone younger or healthier.

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#79

Post by GhettoComputers »

m0zg wrote: post #78
GhettoComputers wrote: post #75

Earlier quoted context omitted.

mRNA as a class is safe. That is not a debate. If he’s worried about the current mRNA vaccine as a single entity he can say that or it’s effects. But he stated there is no evidence mRNA is safe. That is ridiculous as being afraid of your own shadows and that concern is not reasonable. He later says mRNA vaccines aren’t proven to be safe, which is what my post states due to externalities. But he doesn’t know what he’s…

> mRNA as a class is safe. That's like saying "chemicals are safe". I'm pretty sure the same folks who created the Moderna vaccine could just as well cook up a doomsday military grade pathogen using the same equipment and technology, over approximately the same period of time (a weekend). I'm not saying vax is not safe. Its safety record, while not perfect, is relatively well understood in adults (but wasn't at the o…

That is why his statement there is no proof mRNA is safe is so ridiculous. That is not far from saying that there is no proof chemicals are safe. I don’t think we have any disagreement, I agree with you. It’s just ridiculous uninformed blanket skepticism I disagree with.

Re: CoV–2 Spike Impairs DNA Damage Repair – Inhibits V(D)J Recombination in Vitro

#80

Post by m0zg »

GhettoComputers wrote: post #77
m0zg wrote: post #70

Earlier quoted context omitted.

Exactly my thinking as well. Mandates (and other forms of "encouragement") should be by BMI, age, and comorbidities. I'd be covered by a mandate myself, if one existed: high BMI, (treated) high blood pressure, haven't had COVID (yet, that I know of). That's why I chose to vaccinate myself and that's also why my wife chose to vaccinate. I don't have to do it, I'm self employed, I've done it voluntarily. Moreover, if i…

The issue is that the most vulnerable elderly people get terrible effects or die from the immune response. They need to be healthy enough to receive the vaccine, if they’re old and sickly it’s better to vaccinate everyone around them and continue to keep their immune response up. The second most vulnerable elderly people are prime candidates for vaccination though. They’re not as old, more healthy and less likely to…

> elderly people get terrible effects or die from the immune response.

I'm not convinced this is true. As far as I can tell after looking at the data (as thoroughly fucked up and obfuscated as it is) the vaccine is well tolerated in the elderly. Certainly much better tolerated than COVID itself, especially for people 65 and over.

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