31–40 of 98 posts
"Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA..." Can anyone translate?
This is an engineering error at its heart. By design the spike protein were supposed to be expressed and embedded in the surface of the cell where they could be recognized by the immune system. Some proportion of them lingering and having any action within the cell was not foreseen.
Earlier quoted context omitted.
I agree, but the mRNA vaccines factually aren't long lasting. Get your booster if you haven't yet, its important since the protection is about half in under half a year. https://www.thelancet.com/journals/lancet/article/PIIS0140-6...
> I agree, but the mRNA vaccines factually aren't long lasting. Get your booster if you haven't yet, its important since the protection is about half in under half a year. This is misinformation. From your link: > Vaccine effectiveness against hospital admissions for infections with the delta variant for all ages was high overall (93% [95% CI 84–96]) up to 6 months. A post regarding a possible "issue" with the vaccin…
>vaccine effectiveness against infections of the delta variant was high during the first month after full vaccination (93% [95% CI 85–97]) but declined to 53% [39–65] after 4 months.
>Reduction in vaccine effectiveness against SARS-CoV-2 infections over time is probably primarily due to waning immunity with time rather than the delta variant escaping vaccine protection.
Its why its important to get a booster shot. Most people who didn't get vaccinated also don't go to the hospital or die, so its not like that information is significant when the control isn't a black and white difference. People don't want to get infected in the first place so they don't get long covid.
I didn't read the article, but my very basic understanding of mRNA vaccines is that they cause your own cells to produce the spike protein so that your immune system can learn to attack it without actually having the virus present. Does this finding imply that the vaccine would also inhibit DNA damage repair? Or is it more like, in combination with the virus, the spike protein inhibits DNA repair?
edit: this journal might not be worth paying attention to https://en.wikipedia.org/wiki/MDPI#Controversies >Does this finding imply that the vaccine would also inhibit DNA damage repair? Well, yes , but consider the context. If you read the article, and it's almost beyond belief that I have to recommend that you read the article in order to discuss it -- indeed, the information that might assuage your fears is in the…
And that’s the TL;DR folks. Seriously, this distillation makes the choice very easy.
Earlier quoted context omitted.
This is an engineering error at its heart. By design the spike protein were supposed to be expressed and embedded in the surface of the cell where they could be recognized by the immune system. Some proportion of them lingering and having any action within the cell was not foreseen.
Are you implying that covid-19 was engineered/designed? If not, what are you talking about?
Earlier quoted context omitted.
This is an engineering error at its heart. By design the spike protein were supposed to be expressed and embedded in the surface of the cell where they could be recognized by the immune system. Some proportion of them lingering and having any action within the cell was not foreseen.
Are you implying that covid-19 was engineered/designed? If not, what are you talking about?
I didn't read the article, but my very basic understanding of mRNA vaccines is that they cause your own cells to produce the spike protein so that your immune system can learn to attack it without actually having the virus present. Does this finding imply that the vaccine would also inhibit DNA damage repair? Or is it more like, in combination with the virus, the spike protein inhibits DNA repair?
edit: this journal might not be worth paying attention to https://en.wikipedia.org/wiki/MDPI#Controversies >Does this finding imply that the vaccine would also inhibit DNA damage repair? Well, yes , but consider the context. If you read the article, and it's almost beyond belief that I have to recommend that you read the article in order to discuss it -- indeed, the information that might assuage your fears is in the…
Explicitly saying nobody should look into a potential negative side effect of vaccines because they might actually find something is down right scary. Much scarier than any fears of “misinformation”. This kind of thinking is why there is mistrust.
Earlier quoted context omitted.
It does imply that the vaccine would also inhibit DNA damage repair. I think the key question is timescale. I suspect this would be a short-term side effect, with no real impact. If not -- if it's longitudinal -- it could be scary. I can't imagine how that would happen, though. Virus would have the same effect, so this isn't an anti-vax argument.
When you say "the vaccine", do you mean the mRNA vaccines specifically, or all of the vaccines?
I didn't read the article, but my very basic understanding of mRNA vaccines is that they cause your own cells to produce the spike protein so that your immune system can learn to attack it without actually having the virus present. Does this finding imply that the vaccine would also inhibit DNA damage repair? Or is it more like, in combination with the virus, the spike protein inhibits DNA repair?
The spike protein from the vaccine is injected into your muscle and does not circulate through your system.