Live data from Hacker News

Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

thelancet.com

1–10 of 127 posts

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#3
So... How was this not discovered 18 months ago?

There are plenty of people taking fluvoxamine already, which acts as a natural experiment. After a few thousand hospitalizations, this effect size would have been obvious (ie. March 2020). At that point, a double-blind study could have been run, which (if done in a city with many infections) could have given results within weeks.

What bit of health research dropped the ball on this?

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#5
What's interesting is Steve Kirsch was touting this months ago alongside Robert Malone and Bret Weinstein.

That content got banned from YouTube.

Was more or less harm done by stifling this information?

In the desire to drive official therapeutics and vaccines was this potentially not surfaced as fast as it could have been?

I'm not sure. It's good food for thought though.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#6

So... How was this not discovered 18 months ago? There are plenty of people taking fluvoxamine already, which acts as a natural experiment. After a few thousand hospitalizations, this effect size would have been obvious (ie. March 2020). At that point, a double-blind study could have been run, which (if done in a city with many infections) could have given results within weeks. What bit of health research dropped the…

Wouldn't this sort of "obvious" link require tracking every patients entire history? Couldn't it be lost in other confounding factors? This seems like it would require a lot of good data and then strong analysis chops to pull that pattern out.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#7
post #5

What's interesting is Steve Kirsch was touting this months ago alongside Robert Malone and Bret Weinstein. That content got banned from YouTube. Was more or less harm done by stifling this information? In the desire to drive official therapeutics and vaccines was this potentially not surfaced as fast as it could have been? I'm not sure. It's good food for thought though.

Was it specifically because of this one claim, or because of his claims that hydroxychloroquine works and that COVID vaccines are toxic? I think you're doing a disservice by downplaying his history surrounding COVID.

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#8
post #5

What's interesting is Steve Kirsch was touting this months ago alongside Robert Malone and Bret Weinstein. That content got banned from YouTube. Was more or less harm done by stifling this information? In the desire to drive official therapeutics and vaccines was this potentially not surfaced as fast as it could have been? I'm not sure. It's good food for thought though.

I think the issue is how was it proven back then? There are a lot of people promoting ideas, some of which will eventually get clinical backing that they are correct.

Prior to studies being done, how do we evaluate who is a quack and who is correct? There is a lot of harm promoting quack ideas during a pandemic. Based on reputation? Twitter followers? Their passion?

I do not believe anyone censored research and scientific literature that was mainstream nor did they say they can not try to get your theories proven, rather they were basically saying do can not claim you have the truth if there is nothing solid backing you up. Basically skipping showing your work (e.g. peer review), and just saying you have the answer.

I would argue that anyone who had a solution to Covid should rush to get it published in a reputable journal -- because that is how science works. You do not go and make YouTubes first promoting it as the cure first.

Did Steven even have a role in this paper or are these professionals operating completely independently of him? So Steven didn't even bother to make this mainstream? Too much work?

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#9
post #4
post #2

Hey this looks pretty awesome. More early treatment options for COVID-19 is going to save many lives!

Yep. Combined with vaccines we should be able to save more people!

Hopefully it will also help with mortality in the unvaccinated, which is driving >90% of US deaths

Re: Effect of early treatment with fluvoxamine on risk of hospitalization for Covid

#10
post #5

What's interesting is Steve Kirsch was touting this months ago alongside Robert Malone and Bret Weinstein. That content got banned from YouTube. Was more or less harm done by stifling this information? In the desire to drive official therapeutics and vaccines was this potentially not surfaced as fast as it could have been? I'm not sure. It's good food for thought though.

American history is littered with medical salesmen touting miracle cures to desperate ill people. Would you prefer our modern communication mediums be saturated with their pitches or do we want to wait until there is a reasonable scientific consensus before unleashing re-engagement algorithms?
Post reply on HN