21–30 of 193 posts
> PNAS October 26, 2021 118 (43) e2108728118; https://doi.org/10.1073/pnas.2108728118 I'm curious how was this published October 26, 2021? (Currently Oct 15)
PNAS recently moved to a continuous publication process so the paper comes out in the planned issue whenever ready rather than effectively coming out twice: once ahead-of-print and once in the issue.
https://www.pnas.org/page/updates#pnas-continuous-publicatio...
Earlier quoted context omitted.
There are some interesting nasal sprays that wipe out early viral load in the nose and throat that are available right now. ImmuneMist and XClear for example.
ImmuneMist is already facing warnings of regulatory action for their false claims re: covid https://www.ftc.gov/enforcement/warning-letters/warning-lett...
I'm starting to get pretty optimistic. There seem to be a bunch of antivirals with very different mechanisms of action - this one blocks entry of the virus to cells, Molnupiravir fucks up accurate replication of the virus (nucleoside analog), others are protease inhibitors, which are very effective against HIV. There's a caveat, most treatments that look promising don't pan out, but there are a lot in the pipeline an…
mRNA vaccines look extremely promising too. It’s entirely possible that some classes of cancer will be effectively eliminated in our lifetime because of it, along with HIV and/or Malaria. The latter would probably be the biggest reduction in human death and misery since the invention of the Polio vaccine
I know basically nothing about virology, but I remember hearing a podcast a million years ago talking about mRNA vaccines, and I remember after it was over thinking "if this is even half as cool as it sounds to a lay person, the implications of this are huge". It appears that it's substantially more than half as cool as it sounded, and the fact that we are even having discussions about being able to wipe out malaria is mind-boggling to me (in a good way).
I'm starting to get pretty optimistic. There seem to be a bunch of antivirals with very different mechanisms of action - this one blocks entry of the virus to cells, Molnupiravir fucks up accurate replication of the virus (nucleoside analog), others are protease inhibitors, which are very effective against HIV. There's a caveat, most treatments that look promising don't pan out, but there are a lot in the pipeline an…
A limiting factor for the effectiveness of anti-virals for Covid is time. Maximum viral load happens often happens before any symptoms are present, and the most severe diseases occurs weeks after infection as a result of the bodies inflammatory response instead of the virus itself. This means that by the time you know that a patient will have severe Covid-19, it is likely too late for any treatment that is based on i…
Sure, there will always be sceptics, but for large parts of people, organisations and governments having less perverse incentives might improve things a lot.
Earlier quoted context omitted.
https://apnews.com/article/fact-checking-067310377629
I find fact checkers quite interesting in the way they've been deployed over the last few years. As if one source is the "truth" and that settles things. Usually when you get to the end of "false" claims, you find some tidbits that make you wonder... such as: "Several posts circulating online wrongly suggest that the pills are the same because ivermectin also acts like a protease inhibitor and keeps the virus from re…
Could you please explain what exactly did you interpreted from a statement that boils down to "no one showed that this actually works"? The fact check looks pretty cut and dry to me.
I'm starting to get pretty optimistic. There seem to be a bunch of antivirals with very different mechanisms of action - this one blocks entry of the virus to cells, Molnupiravir fucks up accurate replication of the virus (nucleoside analog), others are protease inhibitors, which are very effective against HIV. There's a caveat, most treatments that look promising don't pan out, but there are a lot in the pipeline an…
I'm starting to get pretty optimistic. There seem to be a bunch of antivirals with very different mechanisms of action - this one blocks entry of the virus to cells, Molnupiravir fucks up accurate replication of the virus (nucleoside analog), others are protease inhibitors, which are very effective against HIV. There's a caveat, most treatments that look promising don't pan out, but there are a lot in the pipeline an…
A limiting factor for the effectiveness of anti-virals for Covid is time. Maximum viral load happens often happens before any symptoms are present, and the most severe diseases occurs weeks after infection as a result of the bodies inflammatory response instead of the virus itself. This means that by the time you know that a patient will have severe Covid-19, it is likely too late for any treatment that is based on i…
Earlier quoted context omitted.
mRNA vaccines look extremely promising too. It’s entirely possible that some classes of cancer will be effectively eliminated in our lifetime because of it, along with HIV and/or Malaria. The latter would probably be the biggest reduction in human death and misery since the invention of the Polio vaccine
I've been saying for roughly a year now that if nothing else good can come from Covid, we at the very least are dumping a ton of time and resources and research into mRNA vaccines. I know basically nothing about virology, but I remember hearing a podcast a million years ago talking about mRNA vaccines, and I remember after it was over thinking "if this is even half as cool as it sounds to a lay person, the implicatio…
Earlier quoted context omitted.
ImmuneMist is already facing warnings of regulatory action for their false claims re: covid https://www.ftc.gov/enforcement/warning-letters/warning-lett...
As is XLear https://www.ftc.gov/enforcement/warning-letters/warning-lett...
I'm starting to get pretty optimistic. There seem to be a bunch of antivirals with very different mechanisms of action - this one blocks entry of the virus to cells, Molnupiravir fucks up accurate replication of the virus (nucleoside analog), others are protease inhibitors, which are very effective against HIV. There's a caveat, most treatments that look promising don't pan out, but there are a lot in the pipeline an…
mRNA vaccines look extremely promising too. It’s entirely possible that some classes of cancer will be effectively eliminated in our lifetime because of it, along with HIV and/or Malaria. The latter would probably be the biggest reduction in human death and misery since the invention of the Polio vaccine