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Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

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Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#81
post #78
post #18

Earlier quoted context omitted.

For now. Six months from now you'll need another booster.

It's gonna be an yearly thing, isn't it. Now with a digital pass so you need to get a paid vaccination or be restricted. Bet my life that's what's gonna happen.

It will happen if we tolerate it. Bi-annual COVID booster shots, for life, for the entire population. Big Pharma's wet dream. No employment, entertainment, travel, or shopping if you resist. Constant government surveillance - 'contact tracing'.

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#82
post #57
post #31

Earlier quoted context omitted.

The government's actions I can understand. The courts decisions based on 'unprecedence' events is troublesome. It creates a low barrier for the removal of any rights. An event will happen like this again.

Not to mention, these events are precdented. This is a 1:40 to 1:100 year pandemic; depending on how much of it has to do with modern airlines.

Try once a decade: https://swprs.org/wp-content/uploads/2020/10/sweden-monthly-...

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#83

> Canadian data now provides real world evidence that vaccinated people produce more antibodies if their second shot is delayed This was decided in March 2021 but the UK introduced a three month delay between vaccine shots in January 2021. What was it about the UK data (btw I'm British) that meant it didn't count as "real world" despite being months ahead of Canada? Don't get me wrong, the UK was laughed at for doing…

It's very difficult to take Boris Johnson seriously on any level for a great many people. Even if he was expertly advised and followed the advice many would want to see strong evidence that this occurred before assuming it was just another random whim divorced from reality in support of a particular pose that is difficult for outsiders to understand.

I'm not saying that's a fair analysis and it probably isn't but it is a very widely held one. I know the UK is pretending the herd immunity strategy of encouraging everyone to go to football games because they only infect 5 people actually never happened and was never policy despite the press conferences etc. It seems pretty unlikely to me that people from across the political ideology spectrum got that idea because of a unified Johnson smear.

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Aside it is possible it's a unified smear, of course. We've seen unified smears (nobly or ignobly motivated) of Sanders, Trump and Corbyn to name just 3. (And do you like /any/ of those politicians? A smear is still a smear when you dislike them with vigor.) It's harder to see it here. Johnson's charm works about as well outside of the UK as Trump's in the big coastal cities and Europe.

[1] I have a strong visceral dislike for Trump. The man makes my blood boil and reason hard to cling to. Yet the Russian bounties story in Afghanistan is one place I can look at a man I utterly loathe and note there was a unified smear taking place in the media. I'd be interested if someone has a similar case concerning Johnson. There don't seem to be many consequences for reporting, publishing and repeating utter falsehoods which makes sensible, reasoned, policy analysis by those of us who merely want to vote in a sensible manner increasingly challenging.

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#84
post #78

Earlier quoted context omitted.

It's gonna be an yearly thing, isn't it. Now with a digital pass so you need to get a paid vaccination or be restricted. Bet my life that's what's gonna happen.

It will happen if we tolerate it. Bi-annual COVID booster shots, for life, for the entire population. Big Pharma's wet dream. No employment, entertainment, travel, or shopping if you resist. Constant government surveillance - 'contact tracing'.

I can see the logic of it all and still be deeply concerned where it is leading. It's difficult to work out. There's a lot of heat (satirizing: you're vaccine-denying-murderer spreading evil vs you support the soviet style 1984 dystopia starting now unless you join us in opposing it with guns in the street). There's really not a lot of light.

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#85
post #38

Earlier quoted context omitted.

How did Israel gets enough vaccine by April then? Canada had barely started receiving doses then? I see an awful lot of whitewashing to cover mistakes going on.

a) Canada has 4x the population of Israel b) Israel agreed to the extraordinary term of sharing their data with Pfizer, in exchange for getting doses early, something Canada almost surely won't be willing to do c) The Israeli PM Netanyahu was facing significant electoral challenges and desperately needed a win, so there was a lot of political will

In terms of B that’s called a “patient registry” which is quite common and done in Canada as well. It’s basically a clinical trial post-approval where you aim to capture every patient on the drug. I’d argue Canada’s lack of interest has more to do with capability and overall interest in early access.

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#86
post #75
post #39

Earlier quoted context omitted.

It’s not the exact same spike protein.

Even better? Immune system learns of two (slightly) different ones, making immunity more robust.

That’s the logic, and the argument why actual infection with Covid produces an even better immune response than mixed vaccines.

But that’s by no means a guaranteed outcome. Mixed vaccines could have resulted in mediocre immune response to two different spike protein profiles.

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#87
post #71

Earlier quoted context omitted.

"Unlike the US and Europe, Canada dragged its heels on pre-ordering vaccines" Canada was one of the first countries to pre-order vaccines, signing massive agreements with just about every candidate maker. I'm aware of literally a single deal happening with another country prior to Canada's orders. What thwarted Canada's efforts was that the US defacto nationalized the medical establishment in that country, while Cana…

Not to hijack this too much but the Australian vaccine rollout has been widely panned but much of the problems come down to a choice to rely on domestically manufactured AZ vaccines. In a different timeline if the AZ vaccine hadn’t been associated with rare blood clotting, if Pfizer/Moderna hasn’t been able to scale manufacturing as well that strategy would be looking very good. It’s interesting to think that Canada…

The great hope of Australia's vaccine strategy was the University of Queensland's "Molecular Clamp". Unfortunately the clamp molecule, derived from part of the AIDS virus, triggered false positives in AIDS tests. They used that particular molecule as it was available and time scales were tight. A revised version is being developed with a new clamp molecule, but it won't be ready for the current round of vaccinations.

https://www.abc.net.au/news/health/2021-04-26/university-que...

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#88
post #31

Earlier quoted context omitted.

The government's actions I can understand. The courts decisions based on 'unprecedence' events is troublesome. It creates a low barrier for the removal of any rights. An event will happen like this again.

Removal of rights is one thing that is debatable. Not giving them back when the emergency has been gone and in developed countries everybody who wanted to get vaccinated got it is clearly an overstep.

Haven’t you seen the new excuse? The emergency isn’t over until everybody has gotten the required booster shots, and they are required indefinitely.

Re: Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off

#90

Earlier quoted context omitted.

everyone is required to take pictures of themselves inside their homes at regular intervals That is... bizarre. Very bizarre. Do you have a link to read more?

https://www.reuters.com/world/asia-pacific/australias-two-la... From what I can garner, there are such systems on trial, though as of Sept 16 the trials were on a voluntary basis.

Why would you run trials of this Big Brother system if you weren’t considering making it mandatory?
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