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Evidence That ADHD Is a Genetic Disorder

sciencedaily.com

11–20 of 77 posts

Re: Evidence That ADHD Is a Genetic Disorder

#11
post #9
post #5

Earlier quoted context omitted.

"Let me tell you from personal experience, these people are doing more harm to their children than good." The problem is that the science clearly says the opposite: "At the end of 14 months, core ADHD symptoms were reduced more in the children treated with stimulants than with behavioral therapy. However, at the end of three years, 'medication use was a significant marker not of beneficial outcome, but of deteriorati…

If we're getting into a debate of whether medications can have other effects than intended, I cannot argue that. ADHD and ADD should be treated in completely different ways. People diagnosed with ADHD have a much higher chance of psychotic symptoms than those who are only of the inattentive type. Then there is the old saying, "if you've seen one child with ADHD, you've seen one child with ADHD." In my experience, and…

What you're experiencing now is called the honeymoon period. You can go Google for what people on r/drugs have written about their experiences with this, or you can just wait to find out on your own.

edit: http://www.reddit.com/r/Drugs/comments/excne/advice_needed_h...

Re: Evidence That ADHD Is a Genetic Disorder

#12
post #8

As a child of 8 years old, I was given 120MG of Ritalin per day. I rarely slept the first 2 years. If I did it was around 6am for an hour or so. Then I had to take my morning dose for school. They also wanted me to take a pill to sleep, which felt so horrible I cannot even explain it. I was a zombie in the morning if I took it, then onto the morning ritalin dose. I would just do pushups in my room until 3am some nigh…

120mg as a kid, damn thats a lot.

I took 90 mg as an adult and that was the absolute maximum allowed (in Iceland).

It did me a lot of good but thankfully I am off them now and doing pretty well, meditation is a great substitute.

Re: Evidence That ADHD Is a Genetic Disorder

#13
ADHD is a real problem, but the rate at which it's diagnosed, and the rate that kids are just thrown Ritalin and other drugs is alarming. A child's brain is a very plastic environment that is still developing. The impact it can have on the brain is not as predictable as a developed adult.

It would be foolish not to try more sensible approaches like diet/exercise/parenting FIRST, and if those have no impact, then consider alternatives. However, this is not how parents of today approach problems. They want the quick fix: give my child a pill/shot/instant gratification, so I can get back to my job.

Also, this article is from Sept 2010.. not exactly news is it?

Re: Evidence That ADHD Is a Genetic Disorder

#14
post #8

As a child of 8 years old, I was given 120MG of Ritalin per day. I rarely slept the first 2 years. If I did it was around 6am for an hour or so. Then I had to take my morning dose for school. They also wanted me to take a pill to sleep, which felt so horrible I cannot even explain it. I was a zombie in the morning if I took it, then onto the morning ritalin dose. I would just do pushups in my room until 3am some nigh…

120MG of Ritalin? Sounds absurd.

Re: Evidence That ADHD Is a Genetic Disorder

#15
post #5
post #2

This is welcome news. I recently got diagnosed and after taking the medication, I've found a great increase in the quality of life. There are a few who are very anti-drug when it comes to this condition and their children. Let me tell you from personal experience, these people are doing more harm to their children than good. Education is important. Depending on the severity, each year a parent doesn't take action is…

"Let me tell you from personal experience, these people are doing more harm to their children than good." The problem is that the science clearly says the opposite: "At the end of 14 months, core ADHD symptoms were reduced more in the children treated with stimulants than with behavioral therapy. However, at the end of three years, 'medication use was a significant marker not of beneficial outcome, but of deteriorati…

I don't have time for a full rebuttal, and it may well be true that medication is a worse approach to ADHD treatment than behavioral therapy. However, I want to point out by example that science is not true that "science clearly says" this.

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1. "At the end of 14 months, core ADHD symptoms were reduced more in the children treated with stimulants than with behavioral therapy. However, at the end of three years, 'medication use was a significant marker not of beneficial outcome, but of deterioration. That is, participants using medication in the 24-to-36 month period actually showed increased symptomatology during that interval relative to those not taking medication.'"

If you actually look at the data, it shows that all participants (behavioral, combined therapy, medication only) showed marked improvement at the end of 14 months, then deterioration from the 14 month improvement at 36 months.

In conclusion, all participants showed improvement at 36 months versus their scores at the start of the study.

Additionally, they found that a number of participants who begun in the the medication group stopped using their medication after 14 months (down from 90% at 14 months to 70% at 24-36 months). Whilst, on the converse members from even the behavioral and community care group begun to use medication through out the study (up to 40% in the behavioral group. 60% in the CC group).

Their conclusion says it best: "It would be incorrect to conclude from these results that treatment makes no difference or is not worth pursuing.... medication management-may only make a persistent long term difference if it is continued with the same intensity as during the MTA's initial 14 month period".

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2. "At the end of six years, medication use was 'associated with worse hyperactivity-impulsivity and oppositional defiant disorder symptoms,' and with greater 'overall functional impairment.'"

As compared to whom?

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3. "Within 21 months, 11 percent of children treated with a stimulant for ADHD developed 'psychotic symptoms.'"

ADHD is usually treated at the same age when psychosis is first diagnosed. It could be that ADHD symptoms are positively correlated with psychosis.

A close reading of the paper might actually provide that data.

Even if the side-effect does exist to some degree that does not mean that it is "clear" that the drug isn't beneficial especially considering the 89% of children that didn't experience this side effect.

Traditionally, what is done is more work into identifying those who could suffer from damaging side effects early and shunting them out of a medication program.

----

That's about all I can do now, but essentially there is no indication that stimulant medication is wholly poor performing and that early studies indicating efficacy were flawed.

What there is is evidence that side-effects exist, and preliminary investigation into the degree and distribution of those side-effects.

Additionally there is strong evidence that medication use is variable amongst participants versus other drugs for chronic conditions where drug use is sustained.

Re: Evidence That ADHD Is a Genetic Disorder

#16
post #9
post #5

Earlier quoted context omitted.

"Let me tell you from personal experience, these people are doing more harm to their children than good." The problem is that the science clearly says the opposite: "At the end of 14 months, core ADHD symptoms were reduced more in the children treated with stimulants than with behavioral therapy. However, at the end of three years, 'medication use was a significant marker not of beneficial outcome, but of deteriorati…

If we're getting into a debate of whether medications can have other effects than intended, I cannot argue that. ADHD and ADD should be treated in completely different ways. People diagnosed with ADHD have a much higher chance of psychotic symptoms than those who are only of the inattentive type. Then there is the old saying, "if you've seen one child with ADHD, you've seen one child with ADHD." In my experience, and…

Your experience is yours. How long have you been on medication? What medication specifically?

I've heard that some new meds are not stimulant. They might be good. But the old Ritalin/Adderall stimulants have quite possibly caused the psychotic symptoms you are talking about. That's what they do.

Are you familiar with street meth? Ritlain/Adderall are pharma grade long duration forms of that. They have made me crazy before. And they don't "Halt Depression" they get you so busy you that you won't reflect on yourself.

Artificial increases in motivation are silly. If you aren't inspired on your own to do something, you probably should be doing something else.

Stimulants are much less than perfect and throwing out a pharma grade street drug with the bath water is fine with me. It's drugs or it's not.

There are ways to handle ADD/ADHD without drugs. Change the environment. Forcing kids to take meth is just wrong.

Re: Evidence That ADHD Is a Genetic Disorder

#17
post #9

Earlier quoted context omitted.

If we're getting into a debate of whether medications can have other effects than intended, I cannot argue that. ADHD and ADD should be treated in completely different ways. People diagnosed with ADHD have a much higher chance of psychotic symptoms than those who are only of the inattentive type. Then there is the old saying, "if you've seen one child with ADHD, you've seen one child with ADHD." In my experience, and…

What you're experiencing now is called the honeymoon period. You can go Google for what people on r/drugs have written about their experiences with this, or you can just wait to find out on your own. edit: http://www.reddit.com/r/Drugs/comments/excne/advice_needed_h...

It may be my honeymoon period, but plenty of others who are well past their honeymoon period and still enjoying the benefits of stimulants.

Again, it's not a perfect drug, but it works if you use it as a tool and not as a silver bullet.

Re: Evidence That ADHD Is a Genetic Disorder

#18
post #9
post #5

Earlier quoted context omitted.

"Let me tell you from personal experience, these people are doing more harm to their children than good." The problem is that the science clearly says the opposite: "At the end of 14 months, core ADHD symptoms were reduced more in the children treated with stimulants than with behavioral therapy. However, at the end of three years, 'medication use was a significant marker not of beneficial outcome, but of deteriorati…

If we're getting into a debate of whether medications can have other effects than intended, I cannot argue that. ADHD and ADD should be treated in completely different ways. People diagnosed with ADHD have a much higher chance of psychotic symptoms than those who are only of the inattentive type. Then there is the old saying, "if you've seen one child with ADHD, you've seen one child with ADHD." In my experience, and…

[deleted]

Re: Evidence That ADHD Is a Genetic Disorder

#19
post #12
post #8

As a child of 8 years old, I was given 120MG of Ritalin per day. I rarely slept the first 2 years. If I did it was around 6am for an hour or so. Then I had to take my morning dose for school. They also wanted me to take a pill to sleep, which felt so horrible I cannot even explain it. I was a zombie in the morning if I took it, then onto the morning ritalin dose. I would just do pushups in my room until 3am some nigh…

120mg as a kid, damn thats a lot. I took 90 mg as an adult and that was the absolute maximum allowed (in Iceland). It did me a lot of good but thankfully I am off them now and doing pretty well, meditation is a great substitute.

1988 was the heyday. It was still a 'miracle-drug' at that point. I was the experimental group.

They dialed it down after year or so, although I didn't notice much change.

Re: Evidence That ADHD Is a Genetic Disorder

#20
post #8

As a child of 8 years old, I was given 120MG of Ritalin per day. I rarely slept the first 2 years. If I did it was around 6am for an hour or so. Then I had to take my morning dose for school. They also wanted me to take a pill to sleep, which felt so horrible I cannot even explain it. I was a zombie in the morning if I took it, then onto the morning ritalin dose. I would just do pushups in my room until 3am some nigh…

What are you saying, that people should build corralled pens for children so that they can 'thrive' on their natural ability to bounce from left to right and generally moving about a lot but accomplishing nothing?

Your appeal to emotion argument is detrimental to all those who are (through prejudices like yours) denied treatment for what is an actual, physiological brain defect. 120 mg is a lot, it may have been too much for you, or you may not have ADHD, I don't know. But denying that a disorder exists because you had a bad experience is intellectually dishonest and holding back the treatment of hundreds of thousands if not millions, and social acceptance of treating it.

The science is clear on this point: ADHD exists, it is treatable, and the quality of life of people who have it is improved significantly with medication and behavioral therapy. That methylphenidate works has been widely proven scientifically, and its effects have been studied for decades. It's true that we don't know everything about it, and we will need further studies for decades, but that doesn't take away from the dramatic improvements in functioning that many people get from it.

Your 'argument' seems to be based on 'But I was not myself.'. I'm sorry that you apparently feel that there is some sort of mystical 'true self' that is somehow different when your neural functioning is chemically improved, and I hope that until you come to terms with reality you can live a productive life and be generally happy. But until then, don't be the crab at the bottom of the bucket.

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