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Evidence that overnight fasting could extend healthy lifespan [pdf]

media.nature.com

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Re: Evidence that overnight fasting could extend healthy lifespan [pdf]

#43
post #36
post #33

Earlier quoted context omitted.

edit: commenter shared [0] which disproves my understanding. Intermittent fasting, when controlled for calorie (and protein) intake, had a healthy outcome than a 'normal' diet, but the sample size was only 14 women per group (IF and control). I wish they would have stricter diets in the study. They control for smokers, but I wonder if participants in one group consume alcohol or deep-fried calories more than the othe…

You're understanding is limited. For a nice review check out this one [1]. Although most of 16:8 effects are minor, they build up over time. [1]: https://examine.com/supplements/16-8-intermittent-fasting/

> TRF 2826 ± 412.3 kcal/day, carbohydrates 53.2 ± 1.4 %, fat 24.7 ± 3.1 %, protein 22.1 ± 2.6 %

> ND 3007 ± 444.7 kcal/day, carbohydrates 54.7 ± 2.2 %, fat 23.9 ± 3.5 %, protein 21.4 ± 1.8)

Any ideas why the TRF group has less calories and more protein than the ND group in the linked study linked in the article [0]? _Maybe_ the TRF group has smaller humans than the ND group, but then why would TRF have a higher protein diet?

> Some studies have found that 16:8 can preferentially reduce fat mass while sparing muscle, but further research is still required to confirm this

Bro-Science Body Builders know that a high protein diet + calorie restrictions are perfect for cutting abdominal fat. I don't see what value IF provides here.

[0] - https://pubmed.ncbi.nlm.nih.gov/27737674/

Re: Evidence that overnight fasting could extend healthy lifespan [pdf]

#44

It doesn’t mention that autophagy in humans takes several days. Overnight fasting might help us but not for the reasons implied here.

I’ve never found good research on autophagy. Has anyone pinpointed when it starts?

https://www.medicinenet.com/how_long_do_you_need_to_fast_for...

Says 2-4 days.

Re: Evidence that overnight fasting could extend healthy lifespan [pdf]

#47
post #39
post #36

Earlier quoted context omitted.

You're understanding is limited. For a nice review check out this one [1]. Although most of 16:8 effects are minor, they build up over time. [1]: https://examine.com/supplements/16-8-intermittent-fasting/

For a nice coverage of the effects, here: https://examine.com/supplements/16-8-intermittent-fasting/re...

oo! thank you for this. I updated my comment.

Re: Evidence that overnight fasting could extend healthy lifespan [pdf]

#48
post #30

Earlier quoted context omitted.

Yes, and you "break" the "fast" every morning.

I see what you did there. Good use of the period at the end!

> I see what you did there.

It's not a play on words, "breaking the fast" is where the word comes from :).

Re: Evidence that overnight fasting could extend healthy lifespan [pdf]

#49
post #15

Earlier quoted context omitted.

I am not sure. I have a sister who used to do that and she wasn't overweight neither had any obvious eating disorder. Maybe it was because she was an athlete? I know other people with obvious weight problems that wake up in the middle of the night to eat and maybe for those it might be considered a disorder.

These people that want to live in their 80s or beyond boggle me. Who wants to stick around that long when you have so many contemporaneous failures of the body all crashing down on you? Better to just die catastrophically in your early to mid 70s and save yourself a drab decade or two.

If you're not careful, your body will start failing at age 65 and you'll live a drab decade until croaking at 75.

If you want to avoid that, and want to stay healthy and vibrant until 75, you have pretty much the same goals as someone who wants to live to 95.

Re: Evidence that overnight fasting could extend healthy lifespan [pdf]

#50
post #44

Earlier quoted context omitted.

I’ve never found good research on autophagy. Has anyone pinpointed when it starts?

https://www.medicinenet.com/how_long_do_you_need_to_fast_for... Says 2-4 days.

From the article:

> There are, however, no conclusive studies on humans that indicate an optimal period of fasting to achieve autophagy

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