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Phase3 Trial:Remdesivir Significantly Reduced Risk of Hospitalization with Covid

gilead.com

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Re: Phase3 Trial:Remdesivir Significantly Reduced Risk of Hospitalization with Covid

#11

Post by incrudible »

shapefrog wrote: post #10
incrudible wrote: post #9

Earlier quoted context omitted.

These are age cohort averages. If you die of COVID despite being vaccinated, clearly the vaccine was 0% effective and early treatment could possibly have helped. Either way, 70% is not incredible in my book. The 95% from the booster will not last.

You are confusing the outcomes of 'serious illness' - which you presented numbers for, and 'death'. Yes you are correct to say if something is effective 999,999 in a million, it is 0% effective in the 1 person. As you specifically mention deaths, but present no information regarding it here is the UK data: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsde... All cohorts: 51,281 total covid deaths in the 6…

You picked a source that not age-stratified and also looks at a timeframe when many were not vaccinated in the first place.

I can give you a source for deaths in the past few weeks in Israel, but only stratified between over/under 60:

https://www.covid-datascience.com/post/what-do-new-israeli-d...

The picture is similar: Efficacy of around 70% (two doses) and 95% (fresh booster) against death. This is far from "one in a million". If you age-stratified this data further, you would likely get better efficacy though.

Re: Phase3 Trial:Remdesivir Significantly Reduced Risk of Hospitalization with Covid

#12

Post by shapefrog »

incrudible wrote: post #11
shapefrog wrote: post #10

Earlier quoted context omitted.

You are confusing the outcomes of 'serious illness' - which you presented numbers for, and 'death'. Yes you are correct to say if something is effective 999,999 in a million, it is 0% effective in the 1 person. As you specifically mention deaths, but present no information regarding it here is the UK data: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsde... All cohorts: 51,281 total covid deaths in the 6…

You picked a source that not age-stratified and also looks at a timeframe when many were not vaccinated in the first place. I can give you a source for deaths in the past few weeks in Israel, but only stratified between over/under 60: https://www.covid-datascience.com/post/what-do-new-israeli-d... The picture is similar: Efficacy of around 70% (two doses) and 95% (fresh booster) against death. This is far from "one i…

Assume for the purpose every single one of the ~600 is old. Same outcome. Indeed leaving them in, according to your own source makes vaccines look worse than they are! Given how the large sample size etc is I am more than comfortable taking the UK unstratified data and clncluding the vaccines are effective.

> Because of age confounding, it is crucial to stratify by age groups, and further to remove children from the

Re: Phase3 Trial:Remdesivir Significantly Reduced Risk of Hospitalization with Covid

#13

Post by incrudible »

shapefrog wrote: post #12
incrudible wrote: post #11

Earlier quoted context omitted.

You picked a source that not age-stratified and also looks at a timeframe when many were not vaccinated in the first place. I can give you a source for deaths in the past few weeks in Israel, but only stratified between over/under 60: https://www.covid-datascience.com/post/what-do-new-israeli-d... The picture is similar: Efficacy of around 70% (two doses) and 95% (fresh booster) against death. This is far from "one i…

Assume for the purpose every single one of the ~600 is old. Same outcome. Indeed leaving them in, according to your own source makes vaccines look worse than they are! Given how the large sample size etc is I am more than comfortable taking the UK unstratified data and clncluding the vaccines are effective. > Because of age confounding, it is crucial to stratify by age groups, and further to remove children from the

No matter how you twist and turn it, the vaccines are significantly less effective in the people who need it the most, to the point where a significant amount of deaths, in both absolue and relative terms, occur in the fully vaccinated. That means better options for treatment are still needed. That is the point I am making, nothing else.

Re: Phase3 Trial:Remdesivir Significantly Reduced Risk of Hospitalization with Covid

#14

Post by shapefrog »

incrudible wrote: post #13
shapefrog wrote: post #12

Earlier quoted context omitted.

Assume for the purpose every single one of the ~600 is old. Same outcome. Indeed leaving them in, according to your own source makes vaccines look worse than they are! Given how the large sample size etc is I am more than comfortable taking the UK unstratified data and clncluding the vaccines are effective. > Because of age confounding, it is crucial to stratify by age groups, and further to remove children from the

No matter how you twist and turn it, the vaccines are significantly less effective in the people who need it the most, to the point where a significant amount of deaths, in both absolue and relative terms, occur in the fully vaccinated. That means better options for treatment are still needed. That is the point I am making, nothing else.

You are litterally making shit up by saying a significant amount of deaths, in both absolue and relative terms, occur in the fully vaccinated

Best of luck to you on your propaganda campaign.

Re: Phase3 Trial:Remdesivir Significantly Reduced Risk of Hospitalization with Covid

#15

Post by incrudible »

shapefrog wrote: post #14
incrudible wrote: post #13

Earlier quoted context omitted.

No matter how you twist and turn it, the vaccines are significantly less effective in the people who need it the most, to the point where a significant amount of deaths, in both absolue and relative terms, occur in the fully vaccinated. That means better options for treatment are still needed. That is the point I am making, nothing else.

You are litterally making shit up by saying a significant amount of deaths, in both absolue and relative terms, occur in the fully vaccinated Best of luck to you on your propaganda campaign.

> You are litterally making shit up by saying a significant amount of deaths, in both absolue and relative terms, occur in the fully vaccinated

Let's go back to current UK data: During the delta wave, 1,613 deaths have been fully vaccinated. That's 70% of deaths, despite high vaccine efficacy. If that's not significant, then the other 722 unvaccinated deaths aren't significant either.

https://assets.publishing.service.gov.uk/government/uploads/... (Page 20)

> Best of luck to you on your propaganda campaign.

Same to you.

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