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Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

merck.com

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Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#241

Post by dougmwne »

barbazoo wrote: post #240
dougmwne wrote: post #235

Earlier quoted context omitted.

Here is why this is a conspiracy theory and likely complete bull: there are 190 somthing countries in the world. Many of them have public health systems with socialized healthcare. Many of them are completely free of influence from Merck or the FDA. Ivermectin is cheap and widely available. There is no way Merck and the FDA could suppress a global consensus if the drug was strongly effective. Conspiracy thinking ofte…

> If you are engaging in these patterns of thinking, I recommend you step back, get out of your bubble and your normal context, diversify your information diet and try to ask more pointed questions of the viewpoints you are taking in. And please stop wiggling your eyebrows at us. I am not. I clearly pointed out that I think this is a conspiracy theory. However I should still be allowed to ask questions that help me p…

> If not, could there be some truth to the allegations that Merck somehow is stalling the Ivermectin studies?

You are holding this conspiracy theory up as something that should be discussed and considered as possible truth. You didn't say you believed it, only that it was worth our attention.

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#242

Post by sudosysgen »

b9a2cab5 wrote: post #226
EricE wrote: post #218

I'm sure this won't be patented and instead will be given away for free. Right?

Considering vaccines are widely available and cheap or free, there's no reason this should be given away for free.

Uhm, no they're not. Many countries are struggling to acquire vaccines even today as they waste away in the US.

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#245

Post by freemint »

sudosysgen wrote: post #239
Marsymars wrote: post #120

Earlier quoted context omitted.

I definitely would not want to be taking a mutagenic prophylactically.

I was talking about post exposure prophylaxis. This drug does have mutation concerns. If I'm choosing between a taking the drug right now for 2-3 days in lower doses Vs a 50% chance of taking much higher doses for 2 weeks, id take the former.

The moment you have symptoms peak replication is already over for two da,s. It's to late by then.

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#246

Post by rich_sasha »

mhb wrote: post #133
rich_sasha wrote: post #117

Earlier quoted context omitted.

> Clearly, this patent should be assigned to the federal government, not to Merck How about a proportional slice? That would seem fair. IP and products can have fractional ownership.

What does "fair" have to do with anything? Are you suggesting that your proposal maximizes the amount of health-improving interventions that society will receive in the future? Do you have any reason to conclude that what you're suggesting will be even a slight improvement?

You’re sounding rather aggressive.

It seems reasonable that if I finance X% of something, I get to enjoy X% of it. Or Y%, adjusted for non-monetary investment by someone else.

It seems strange that the state finances (drug development) research, the companies say “cheers” and proceed to keep all the profits.

Such profits could for example go towards universal health care improvements.

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#247

Post by _Microft »

EricE wrote: post #218

I'm sure this won't be patented and instead will be given away for free. Right?

Trying to improve my skills in recognizing denialism, I would say that this was the “Nefarious Intent” technique, wrapped in a layer of sarcasm?

https://doctorow.medium.com/a-denialism-taxonomy-eeb1a276684...

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#248

Post by [deleted] »

rory wrote: post #86
lsternlicht wrote: post #43

Phase 3 trial was stopped on a positive interim analysis by DSMB and in consultation with FDA Interim analysis was performed on approximately half of the total enrolled patients (775 of the 1550). Trial included many delta and other variant patients ————— Efficacy • ~50% reduction in hospitalization (14.1% PBO vs 7.3% drug) • 100% reduction in deaths (8 PBO vs 0 drug) ————— Safety • fewer adverse reactions in the dru…

Is 40% adverse reaction to a placebo typical? Really makes me wonder how many "side effects" are in our heads..

[deleted]

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#249

Post by nradov »

programmarchy wrote: post #127
rory wrote: post #86

Earlier quoted context omitted.

Is 40% adverse reaction to a placebo typical? Really makes me wonder how many "side effects" are in our heads..

Couldn’t the adverse events in the placebo arm actually be caused by Covid?

Probably. There was no uninfected control group.

Re: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

#250

Post by guilhas »

ceejayoz wrote: post #237
guilhas wrote: post #228

Earlier quoted context omitted.

"Reuters is seeking comment on the legal specificities of the FDA approval and will update the check in due course." How convenient. Pfizer states that both vaccines are legally different. Meaning even with the same formula 'Pfizer' vaccine has no liability for compensation claims, 'Comirnaty' has but it is not being supplied

"I can't be bothered to Google" and "convenient" aren't quite the same thing. The information you seek is readily available. The two have the exact same liability setup. https://www.washingtonpost.com/politics/2021/08/30/false-cla... > “There are no liability or compensation differences between a countermeasure approved under an EUA or one that has received full FDA approval,” confirmed an HHS spokesperson. Pfizer al…

"The PREP Act designation means that claims related to coronavirus vaccines are covered by the Countermeasures Injury Compensation Program (CICP), not the National Vaccine Injury Compensation Program (VICP), which was set up to handle vaccine lawsuits. ... The liability protections afforded under the PREP Act are tied to the declared public health emergency and not whether the vaccine is sold under an EUA"

OK... because of the "state of emergency" there is actually no compensations for either the vaccines

I feel so much safer

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