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Little Exercise, Big Effects: Reversing Aging

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Re: Little Exercise, Big Effects: Reversing Aging

#41

Post by asifjamil »

sorbus wrote: post #39
asifjamil wrote: post #32

Earlier quoted context omitted.

not sure what you mean. i was pointing out an opposite effect.

The above poster is - as I understand it - pointing out that this study does not necessarily contradict the hypothesis you mentioned. A small amount of exercise is shown to be beneficial, but it is entirely possible that larger amounts of exercise are detrimental. Do you know if any research has been done into that hypothesis? Because - failing a confirming study - it does not seem to fit with anything I've heard. I…

here is a study that does not correlate exercise but just faster metabolism in general (through an active hormone)

> http://www.sciencedaily.com/releases/2006/10/061010022316.ht...

"The study further strengthens the theory that the faster an animal's metabolism, the shorter its life, and vice versa"

Re: Little Exercise, Big Effects: Reversing Aging

#42

Post by [deleted] »

Mz wrote: post #33
kragen wrote: post #31

Earlier quoted context omitted.

I looked it up, and I think "CF" means "cystic fibrosis", a congenital lung disease that is usually fatal in early life.

Yes, it stands for cystic fibrosis. Average life expectancy in the US is currently around 36 or 37, way up from age 18 roughly 18 or 20 years ago. I was diagnosed just before my 36th birthday with a milder classification of it which is emerging and is most often called "atypical cystic fibrosis". I spent a year at death's door. It's been a long haul back from there. It's not really a lung disease. It's a genetic diso…

[deleted]

Re: Little Exercise, Big Effects: Reversing Aging

#43

Post by skybrian »

Alex3917 wrote: post #15
Cushman wrote: post #12

Earlier quoted context omitted.

If it's a receptor thing, it wouldn't only apply to phytocannibanoids, right? I'm given to understand there are a number of synthetic cannabinoid receptor agonists with much higher affinity and/or selectivity than the phytocannabinoids. Are you aware of any research into the potential differences? I suppose it wouldn't make much difference, since as you say it only takes a tiny amount of cannabis despite THC being on…

"Are you aware of any research into the potential differences?" Not off the top of my head, but here are some links to 'databases' of hundreds or thousands of research articles on cannabinoids: http://www.letfreedomgrow.com/cmu/GrannysList-Jan2011.pdf http://www.cannabis-med.org/studies/study.php http://www.cannabis-med.org/index.php?lng=en In general though I think cannabis is a good example of why plant-based medic…

re: "when one molecule in a plant acts as a poison, then generally there will be some other molecule in the plant to counteract that poison"

How does that happen? From an evolutionary point of view, it seems a bit unlikely. Unless it's part of the plant's reproductive strategy, a plant's goal is usually not to be eaten. (However, animals often evolve to counteract plants' defenses.)

Re: Little Exercise, Big Effects: Reversing Aging

#44

Post by Alex3917 »

skybrian wrote: post #43
Alex3917 wrote: post #15

Earlier quoted context omitted.

"Are you aware of any research into the potential differences?" Not off the top of my head, but here are some links to 'databases' of hundreds or thousands of research articles on cannabinoids: http://www.letfreedomgrow.com/cmu/GrannysList-Jan2011.pdf http://www.cannabis-med.org/studies/study.php http://www.cannabis-med.org/index.php?lng=en In general though I think cannabis is a good example of why plant-based medic…

re: "when one molecule in a plant acts as a poison, then generally there will be some other molecule in the plant to counteract that poison" How does that happen? From an evolutionary point of view, it seems a bit unlikely. Unless it's part of the plant's reproductive strategy, a plant's goal is usually not to be eaten. (However, animals often evolve to counteract plants' defenses.)

Mutation 'A' has has both benefits and drawbacks, so mutation 'B' fixes some of those drawbacks. Sure, it's good for a plant to be poisonous to animals that want to eat it, but not at the expense of poisoning itself.

Re: Little Exercise, Big Effects: Reversing Aging

#45

Post by sliverstorm »

AngryParsley wrote: post #38
asifjamil wrote: post #17

Interesting article. I remember reading somewhere the opposite hypothesis. The argument went like this: more exercise --> faster metabolism --> faster consumption of your body utilities --> lower life expectancy

Exercise does cause damage to your body, both structural and oxidative. Fortunately, that damage triggers repair mechanisms which make you stronger than before. See http://en.wikipedia.org/wiki/Hormesis#Physical_exercise An aside: Reading this article made me wonder why I tasted blood after particularly hard workouts. Apparently the heart can pump with enough pressure to rupture some of the capillaries in your lungs.…

Seriously, how can one not already realize this? You can of course work yourself to death, but you'd think people would have noticed how much healthier they feel when they have been exercising, and how quickly they deteriorate when they haven't.

Re: Little Exercise, Big Effects: Reversing Aging

#47

Post by evgen »

danielharan wrote: post #11
Alex3917 wrote: post #5

For what it's worth, cannabis also prevents neuroinflammation, even in extremely low doses: http://www.youtube.com/watch?v=2uVXs6CY2ps http://www.freedomtoexhale.com/clinical.pdf The endocannabinoid system seems to be the main mechanism our bodies use to naturally regulate inflammation. My understanding is that there is a growing belief among cannabinoid researchers that our cannabinoid receptors can get blocked as w…

Cannabis as a treatment for Alzheimer's would be rather ironic, given its current reputation.

As there is a rather large cohort of regular and past cannabis smokers entering into prime Alzheimer years we are going to see if this is true within the decade and do not even need to fund a study. If the Alzheimer rate starts to drop then this is worth further research, but if not I will begin to suspect some people are blowing some rather fragrant smoke on this issue...

Re: Little Exercise, Big Effects: Reversing Aging

#48

Post by roel_v »

Alex3917 wrote: post #9
d2 wrote: post #6

Earlier quoted context omitted.

The problem is that I feel less smart and less motivated for 2 weeks after smoking a joint.

Then don't smoke a joint. The standard sized joints that NIDA hands out for research are 0.7 grams. The amount needed to get this anti-inflammatory effect is roughly .02 grams, in other words 1 / 35th of a joint. There are also two different ways that you can get the same health benefits without any psychoactive side effects. First, you can get high-CBD weed. CBD is a non-psychoactive cannabinoid that basically cance…

"The standard sized joints that NIDA hands out for research are 0.7 grams."

Really? That seems like a lot. I was a sporadic recreational smoker about 15 years ago, we bought marihuana one gram at a time and that gram would last us a weekend. Maybe the difference is in THC content; I bought in the Netherlands where quality is generally high and THC concentrations relatively high in higher-end varieties, from what I understand (I don't have experience with foreign varieties to compare it with). Then again, our usage customs are different from elsewhere in the world, too; we rolled joints out of tobacco and only sprinkled on some marihuana. When I told that to Americans they'd look at me as if I was crazy.

Re: Little Exercise, Big Effects: Reversing Aging

#49

Post by adrianN »

Alex3917 wrote: post #44
skybrian wrote: post #43

Earlier quoted context omitted.

re: "when one molecule in a plant acts as a poison, then generally there will be some other molecule in the plant to counteract that poison" How does that happen? From an evolutionary point of view, it seems a bit unlikely. Unless it's part of the plant's reproductive strategy, a plant's goal is usually not to be eaten. (However, animals often evolve to counteract plants' defenses.)

Mutation 'A' has has both benefits and drawbacks, so mutation 'B' fixes some of those drawbacks. Sure, it's good for a plant to be poisonous to animals that want to eat it, but not at the expense of poisoning itself.

Plant biochemistry is sufficiently different that they are not susceptible to poisons that affect mammals.

Re: Little Exercise, Big Effects: Reversing Aging

#50

Post by narag »

skybrian wrote: post #43
Alex3917 wrote: post #15

Earlier quoted context omitted.

"Are you aware of any research into the potential differences?" Not off the top of my head, but here are some links to 'databases' of hundreds or thousands of research articles on cannabinoids: http://www.letfreedomgrow.com/cmu/GrannysList-Jan2011.pdf http://www.cannabis-med.org/studies/study.php http://www.cannabis-med.org/index.php?lng=en In general though I think cannabis is a good example of why plant-based medic…

re: "when one molecule in a plant acts as a poison, then generally there will be some other molecule in the plant to counteract that poison" How does that happen? From an evolutionary point of view, it seems a bit unlikely. Unless it's part of the plant's reproductive strategy, a plant's goal is usually not to be eaten. (However, animals often evolve to counteract plants' defenses.)

Some plants make delicious fruits that get their seeds spread.
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