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Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

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Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#31

Post by lambdaba »

ezekiel68 wrote: post #26
vncecartersknee wrote: post #20

Earlier quoted context omitted.

Ivermectin is an FDA approved drug and is regularly prescribed to humans. Sure, it probably doesn't do anything for covid but it's not just 'horse dewormer'.

You can remove the "probably". The manufacturer of Ivermectin states there is no scientific evidence [0] supporting the use of the drug for COVID-19. So much for the notion some espouse that "Big Pharma" pushes their drugs on us without fail. [0] https://www.merck.com/news/merck-statement-on-ivermectin-use...

It is out of patent

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#32

Post by taf2 »

_Microft wrote: post #9
kragen wrote: post #8

Earlier quoted context omitted.

What's "ATA"? The scammy-looking commercial page you linked doesn't mention it.

I found something. "ata" seems to mean "atmosphere absolute" and describes the total pressure: "The ata unit is used in place of atm to indicate the total pressure of the system, compared to a vacuum. For example, underwater pressure of 3 ata would mean that this pressure includes 1 atm of air pressure and thus 2 atm due to the water." , from https://en.wikipedia.org/wiki/Standard_atmosphere_(unit)#Pre...

Makes me think of the air commercial from Lorax- https://youtu.be/NWZUp2KF5ls

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#33

Post by rbanffy »

easytiger wrote: post #21
robbedpeter wrote: post #17

Earlier quoted context omitted.

60 sessions, 90 minutes, 100% oxygen via mask with breaks every 20 minutes, over 3 months, 5 per week. Seems like this is a great thing, hopefully it pans out over larger populations of patients.

100% oxygen under high pressure is dangerous

My guess is that the mask is the only source of pure oxygen and that the rest of the atmosphere in the chamber has less oxygen than atmospheric air, making it still breathable because of the higher pressure.

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#34

Post by rbanffy »

sgeisler wrote: post #18

If this turns out to be true I wonder if it'd be practical (given the financial resources) to have pressure sealed rooms that you spend a lot of time in at home (e.g. your office). These could be precisely controlled (O2, CO2 levels, pressure, …) and possibly both increase current and future performance. The main problem seems the time needed to exit because an abrupt loss of pressure would be hazardous. But if you h…

2ATA is like a 10 meter dive. I don’t think you’d need to decompress after a 90 minute dive like that.

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#35

Post by lambdaba »

zzt123 wrote: post #29

Thoughts that popped up: 1. Isn’t hyperbaric therapy used by athletes to reduce inflammation? 2. Isn’t the failure of the amyloid hypothesis leading to researchers considering whether inflammation is the progenitor of Alzheimer’s? So if hyperbaric therapy does work… could that be a sign in favor of the inflammation hypothesis? Although, the authors suggest the results are due to improved oxygenation rather than any a…

I think the etiology is best summed up as "energy deficiency", basically the mitochondria aren't able to provide enough energy. Nutritional repletion, ketogenic diets, ketone supplementation (specifically ketone esters) and everything else that improves energy supply / circumvents issues (impaired glucose metabolism being #1) will help.

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#37

Post by api »

sgeisler wrote: post #18

If this turns out to be true I wonder if it'd be practical (given the financial resources) to have pressure sealed rooms that you spend a lot of time in at home (e.g. your office). These could be precisely controlled (O2, CO2 levels, pressure, …) and possibly both increase current and future performance. The main problem seems the time needed to exit because an abrupt loss of pressure would be hazardous. But if you h…

Depends on your financial resources.

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#38

Post by pivo »

koolba wrote: post #36

Is this the same thing as scuba diving? And if so, can we look at the medical history of scuba divers to see the relative prevalence of Alzheimer’s?

Scuba divers don’t breathe pure oxygen, so that’s one difference

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#39

Post by spuz »

harryleeming wrote: post #7

I'm using 2.4ATA 90min back to back sessions to treat my covid induced brain fog, with great results. It's the first time in a year I can think clearly. Anyone with long covid should seriously look into this as a treatment, it has some solid science behind it and is very safe, albeit expensive. At this point I've tried 14 different drugs, not a single thing has moved the needle except this. More info here on it for l…

What do you mean by "back to back sessions"? How many sessions are we talking about here? What happens between one session and the next?

Re: Hyperbaric oxygen therapy reverses hallmarks of Alzheimer’s disease and dementia

#40

Post by robbiep »

zzt123 wrote: post #29

Thoughts that popped up: 1. Isn’t hyperbaric therapy used by athletes to reduce inflammation? 2. Isn’t the failure of the amyloid hypothesis leading to researchers considering whether inflammation is the progenitor of Alzheimer’s? So if hyperbaric therapy does work… could that be a sign in favor of the inflammation hypothesis? Although, the authors suggest the results are due to improved oxygenation rather than any a…

The amyloid hypothesis is not dead - just like the tau hypothesis is not dead. The $1m question is what role do the proteins play and at what stage and to what degree
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