Spread of Delta variant driven by both immune escape and increased infectivity
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Re: Spread of Delta variant driven by both immune escape and increased infectivity
#2I was told this is a pandemic of the unvaccinated.
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#3> it takes eight times as many antibodies from a vaccinated individual to block the virus
If this is the case, then how can we explain how vaccinated individuals experience less severe symptoms and fewer deaths? Is it because once vaccinated, the immune system is able to respond to this 8x higher demand?
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#4"immune escape"
Remember when we used to use non-bullshit language and just call it: Vaccine failure?
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#5I was told this is a pandemic of the unvaccinated.
What that means is that the unvaccinated are much more likely to become seriously ill if infected:
https://www.axios.com/unvaccinated-hospitalized-covid-60dc90...
It does not mean that the vaccinated cannot spread disease, however.
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#6> it takes eight times as many antibodies from a vaccinated individual to block the virus If this is the case, then how can we explain how vaccinated individuals experience less severe symptoms and fewer deaths? Is it because once vaccinated, the immune system is able to respond to this 8x higher demand?
It does not necessarily mean that virus is 8 times more effective in the general case, just that it takes more resources to battle it.
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#7"immune escape" Remember when we used to use non-bullshit language and just call it: Vaccine failure?
The virus mutates quickly so the vaccine can't be expected to be as effective at new variants compared to the variants it was designed to combat.
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#8I was told this is a pandemic of the unvaccinated.
What that means is that the unvaccinated are much more likely to become seriously ill if infected: https://www.axios.com/unvaccinated-hospitalized-covid-60dc90... It does not mean that the vaccinated cannot spread disease, however.
There is presently to my understanding a lot of claims of severity reduction, but I would like to see evidence and an explanation for it. My working model is that a consistent alternative explanation is the vaccine reduces infection risk dramatically but once infected severity can be the same.
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#9> it takes eight times as many antibodies from a vaccinated individual to block the virus If this is the case, then how can we explain how vaccinated individuals experience less severe symptoms and fewer deaths? Is it because once vaccinated, the immune system is able to respond to this 8x higher demand?
Every article that leads with this kind of stat is guilty of lying by omission. The typical immune response produces 10,000-100,000 times more antibodies than “necessary” to fight an infection.
If delta needs 8x more antibodies, then, well, our immune response is only overkill by a factor of 1,250-12,500.
Perhaps that’s enough for some of the virus to escape. But it’s still plenty to prevent severe illness!
Of course, these are just averages, and the 8x number does mean that people who have a depressed immune response are more likely to just not have enough antibody production, though the relationship between “8x” and this response is complex.
And in reality, transmission is driven in part by how much viral replication happens before antibodies are generated in large numbers. Delta is also better at this, presumably.
Re: Spread of Delta variant driven by both immune escape and increased infectivity
#10"immune escape" Remember when we used to use non-bullshit language and just call it: Vaccine failure?
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