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Melatonin: Much More Than You Wanted to Know (2018)

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Re: Melatonin: Much More Than You Wanted to Know (2018)

#111

Post by detaro »

bserge wrote: post #93
Sunspark wrote: post #11

Melatonin is a hormone, and is contraindicated for those with existing or predisposition to mental health conditions. In fact, that used to be a warning on the label in NY state. It's not something to play with.

It is if you accept the risks. Everything should be something to "play with". Never worked for me in any dosage, anyway, hopefully it works for others. Doesn't really matter in Europe since it's prescription only like anything else half useful. Living like a bunch of idiot slaves over here.

It's not universally prescription-only in Europe. (E.g. here in Germany it is if packaged as medicine, but lower doses are available as non-medical products)

EDIT: looked it up, the latter category is also authorized through EU regulations, so likely EU-wide unless individual countries have specifically decided to ban them (which I think they still can in this case)

Re: Melatonin: Much More Than You Wanted to Know (2018)

#112

Post by Tenoke »

playcache wrote: post #109
Tenoke wrote: post #103

Earlier quoted context omitted.

Caffeine is not just harmless, every meta-analysis suggests it's beneficial for the majority and actively reduces all-cause mortality. I've quit it for months at a time but it hasn't made me feel less tired when I do, the opposite in fact. Of course, there's people like you for which it helps less than hurts but all large studies I can find suggest you are in the minority, not majority.

> Caffeine is not just harmless, every meta-analysis suggests it's beneficial for the majority and actively reduces all-cause mortality. You're conflating caffeine with coffee, specifically coffees non-caffeine properties. If you're referring to the Harvard study, that is coffee and its antioxidant properties, they even state [0] "and it doesn’t appear to matter if the coffee is caffeinated or decaf, brewed or instan…

Yes, I meant coffee though other common methods of ingesting caffeine like tea don't seem to be far off. And no, there's other studies (not sure which one this is from the article you linked).

This recent meta-analysis reviews 40 studies.

https://pubmed.ncbi.nlm.nih.gov/31055709/

Re: Melatonin: Much More Than You Wanted to Know (2018)

#113

Post by TimMeade »

scrollaway wrote: post #107
lamontcg wrote: post #4

> the correct dose A single correct dose is a myth. The author even sort of notes that with the differences between teenagers, 25 year olds and the elderly. There's also a wide variety of sleep disorders which are touched on in the article. I've suffered with 2.5mg before for long enough to understand that it doesn't work for me, no matter how many studies you have with 95% CL that the dose is much lower. The 5mg tab…

I’m 30, with sleep disorder that fits exactly what you are describing. I’ll share my own anecdote. I've taken melatonin in 0.3mg sublingual doses, it worked perfectly. It’s incredible the control it gives me over my sleep after having none for decades. However it leaves me unmotivated the next day, like I don’t want to get out of bed and if I do, I don’t want to get out of the house or do anything. I thought it was c…

Concur. My sleep issues are not severe enough to risk the "do nothing" next day. Only on exceptional bad trends do I use melatonin now. but I may try some of the variants in this.

Re: Melatonin: Much More Than You Wanted to Know (2018)

#114

Post by lugged »

lamontcg wrote: post #4

> the correct dose A single correct dose is a myth. The author even sort of notes that with the differences between teenagers, 25 year olds and the elderly. There's also a wide variety of sleep disorders which are touched on in the article. I've suffered with 2.5mg before for long enough to understand that it doesn't work for me, no matter how many studies you have with 95% CL that the dose is much lower. The 5mg tab…

Try full spectrum CBD if you're in lucky enough position to access it.

Helped me get enough sleep that my anxiety and ADD became 10x moreanageable. (ADD meds don't work for me, they blow up my anxiety.)

Re: Melatonin: Much More Than You Wanted to Know (2018)

#115

Post by oiadscient »

yosito wrote: post #53
lamontcg wrote: post #4

> the correct dose A single correct dose is a myth. The author even sort of notes that with the differences between teenagers, 25 year olds and the elderly. There's also a wide variety of sleep disorders which are touched on in the article. I've suffered with 2.5mg before for long enough to understand that it doesn't work for me, no matter how many studies you have with 95% CL that the dose is much lower. The 5mg tab…

Melatonin is not like a sleeping pill where more will necessarily make you more drowsy. It is a hormone that signals to your body that it is time to sleep. I can't find it right now, but there was a study of different doses in a large number of people that determined that just 0.2mg was more effective than larger doses for most people. And I've found that's true for me too. When I use melatonin, I use 0.2mg, and I fa…

Melatonin is not a hormone. It is a multi tasking antioxidant molecule. It is also 3 billion years old.

Re: Melatonin: Much More Than You Wanted to Know (2018)

#116

Post by oiadscient »

yosito wrote: post #55

Melatonin is not like a sleeping pill where more will necessarily make you more drowsy. It is a hormone that signals to your body that it is time to sleep. I can't find it right now, but there was a study of different doses in a large number of people that determined that just 0.2mg was more effective than larger doses for most people. And I've found that's true for me too. When I use melatonin, I use 0.2mg, and I fa…

Melatonin is not a hormone.

Re: Melatonin: Much More Than You Wanted to Know (2018)

#117

Post by oiadscient »

joelrunyon wrote: post #57
yosito wrote: post #55

Melatonin is not like a sleeping pill where more will necessarily make you more drowsy. It is a hormone that signals to your body that it is time to sleep. I can't find it right now, but there was a study of different doses in a large number of people that determined that just 0.2mg was more effective than larger doses for most people. And I've found that's true for me too. When I use melatonin, I use 0.2mg, and I fa…

It's referenced in the article - https://academic.oup.com/jcem/article/86/10/4727/2849013 In general - I'm surprised people take melatonin so casually without realizing that it's a hormone - not a mineral or amino acid like other sleep aids - https://impossible.co/blogs/health/melatonin-side-effects

It’s not a hormone. It’s an antioxidant.

Re: Melatonin: Much More Than You Wanted to Know (2018)

#118

Post by detaro »

oiadscient wrote: post #117
joelrunyon wrote: post #57

Earlier quoted context omitted.

It's referenced in the article - https://academic.oup.com/jcem/article/86/10/4727/2849013 In general - I'm surprised people take melatonin so casually without realizing that it's a hormone - not a mineral or amino acid like other sleep aids - https://impossible.co/blogs/health/melatonin-side-effects

It’s not a hormone. It’s an antioxidant.

It's both.

Re: Melatonin: Much More Than You Wanted to Know (2018)

#119

Post by concordDance »

oiadscient wrote: post #115
yosito wrote: post #53

Earlier quoted context omitted.

Melatonin is not like a sleeping pill where more will necessarily make you more drowsy. It is a hormone that signals to your body that it is time to sleep. I can't find it right now, but there was a study of different doses in a large number of people that determined that just 0.2mg was more effective than larger doses for most people. And I've found that's true for me too. When I use melatonin, I use 0.2mg, and I fa…

Melatonin is not a hormone. It is a multi tasking antioxidant molecule. It is also 3 billion years old.

Citation?

Re: Melatonin: Much More Than You Wanted to Know (2018)

#120

Post by oiadscient »

winrid wrote: post #23

What I liked about melatonin was the YEAH READY TO GO when waking up. Useful when my schedule was working on the car before work. But I really try not to take it anymore. The blue light glasses are sufficient.

As soon as your skin comes in contact with light it destroys the melatonin. Your eye balls aren’t the only thing that respond to light.
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