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Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

thinkcivics.com

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Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#121
post #106
post #81

Earlier quoted context omitted.

We don't need to. People could be given the option of testing, or of going into isolation for the incubation period. Several countries had great effect from ordering a lockdown and testing the entire population over a day or two, releasing those who are negative from lockdown, and repeating this process multiple times in badly affected areas. Slovakia did this and it seems to have been extremely effective, though obv…

Irrelevant. What appeared to work temporarily in Slovakia last year has no bearing on management of the more contagious Delta variant. Community transmission in most countries is so widespread now that there's simply no practical way to isolate so many people. It's just too late for that to work.

I'm not in one of those countries. I'm in Canada and the medium-sized city I live in has a dozen cases a day, which is an increase over the last few months. The large majority have not contracted it here yet. We continue to use mass testing and partial restrictions to control the rates, along with vaccination. I have no idea if this is a winning proposition in the long run especially with the new contagious variants. But it does seem to work in terms of case numbers so far.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#122

Earlier quoted context omitted.

We don’t have any long term data on Covid infection either. Why risk children’s lives?

Because the vaccine is a risk factor on its own as well. Do you not agree with that?

No, not at all, if you understand how the vaccine works you wouldn’t either.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#123

I know this is a controversial take, but it should be in our national interest to get young children exposed and gain natural immunity, and avoid giving them the vaccine we have so little long-term data on. According to the CDC, 450 kids (0-18yo) died from Covid-19 since Jan 2020. A total of 4.6M kids tested positive since then. In the much shorter 2017-2018 Flu season, ~650 kids (0-17) died. We really have to keep t…

It is not controversial. It is what data strongly indicates, and should be the top comment. As a parent of school age children and with impending school reopening I have recently participated in Covid discussions on this forum to learn more (thanks to people posting and engaging in polite conversation). I had some idea that Covid was less dangerous for kids, but had no idea how much less. I am shocked by the disconnect between data and the public health discourse in this country (USA) pertaining to Covid and kids. On the bright side, I am heartened that the risks for kids are minimal and entirely acceptable, with or without masks, vaccines, lockdowns, school closures, covid passports and whatnot. Though please stay at home if you have symptoms, this is not the time for foolish Covid parties.

Bottom line: Life involves risk, and kids are too subject to some small, but not zero risk. The Covid fatality rate for children is 1/1000 the fatality rate for old people, in line with other risks kids face daily in their lives. For all intents and purposes there are 2 different pandemics: mostly normal for kids and 0.2-1.0% IFR for adults. As an adult, take the vaccine ASAP (I did). But please stop assuming that kids share the same risk profile. They are emphatically LESS likely to develop complications. After infection, they are likely to buildup strong natural immunity against future strains (see OP article). Caveat: the virus mutates and/or CDC estimates may be wrong, so the situation may deteriorate in the future.

* For 0-17s, total 'deaths involving covid' as of 08/25 is actually a bit smaller: 385. For comparison, 'deaths involving influenza' are 188, in influenza-suppressed season. https://www.cdc.gov/nchs/nvss/vsrr/covid_weekly/index.htm.

* CDC estimates that a full 26M kids were infected by Covid, for a fatality rate of 14/M. Total number of kids is 78M, so even the absolute numbers won't get catastrophically worse as long as the virulence of the virus stays the same. https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/burd...

* The total number of school age children fatalities from all cases in US is 5,497, for a 134/M fatality rate. Covid is 10 times less dangerous than just living as a kid. Just the drowning fatality rate is 10/M, same ballpark as Covid. https://www.cdc.gov/nchs/fastats/child-health.htm

* Unfortunately, not all kids are equally healthy. In the first year of the pandemic, 25 kids died in UK. 'around 15 had life-limiting or underlying conditions, including 13 living with complex neuro-disabilities'. '6 had no underlying conditions'. No CDC data. https://www.bbc.com/news/health-57766717

* Whenever you hear 'the hospitals are filling up', do they specifically provide Covid numbers, or are leaving you to fill in the blanks and guess 'Covid'. Tennessee Health Commissioner: 'Children’s hospitals here are on pace to be completely full by the end of next week. Which ones? “All of them,” she said'. Reality: As of 07/31, 41 with enterovirus, 22 with RSV, 10 with Covid, 8 with adenovirus, plus some small tail. No CDC data. https://twitter.com/ifihadastick/status/1423326573185454080

* The CDC director, Rochelle P Walensky, is a co-author of the infamous John Snow Memo, claiming 'Furthermore, there is no evidence for lasting protective immunity to SARS-CoV-2 following natural infection, and the endemic transmission that would be the consequence of waning immunity would present a risk to vulnerable populations for the indefinite future.'. This has been a cornerstone for draconic Covid policies, and has been recently debunked by a number of studies, including the OP article. Shame. https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#124
post #104

Earlier quoted context omitted.

> Natural immunity comes with a 10--25x greater risk of death. No it doesn't. There are O(100) deaths from O(1 billion) vaccinations. That's about 100000x lower risk than from Covid itself, not just 10-25x.

I'm looking for a source, though the 25x factor was part of the 29 July 2021 CDC leaked report. I'm happy to correct / update my comment with a reputable source. From US CDC: Reports of death after COVID-19 vaccination are rare. More than 363 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through August 23, 2021. During this time, VAERS received 6,968 reports of deat…

If we are going with differentiating "all causes" then surely this should be done with infections as well? I don't have numbers on hand but the last CDC report I saw (March 2020 to 2021 I think it was) had only 740 deaths "from [Delta variant of] COVID-19" compared to a few hundred thousand of "all causes" (with COVID). Granted even if those numbers are accurately relayed by my memory (and I doubt they are) the Delta stuff didn't take off until much later, but I'm kinda just making a point here. What that point is I dunno, but I'd just like more apples to apples comparisons in these discussions.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#125
post #65

Natural immunity comes with a 10--25x greater risk of death, possibly much higher (see update) by COVID itself . (The risk from the vaccine, without a Covid infection, is effectively nil based on hundreds of millions of doses administered.) Natural immunity comes with a ~9x greater risk of hospitalisation, again from Covid itself. There's effectively no risk from the vaccine, again with hundreds of millions of doses…

>This information is interesting, but a poor basis on which to shift policy from vaccination to infecting the entire population and blessing the survivors. Only if we were starting from a point of nobody having been infected already. In LA, Chicago, NYC, Miami, ~50% of the population has been infected[0]. If the Israeli study is accurate, then all of those people should be considered as immune as vaccinated, therefor…

Those populations may not be comparable, the headline numbers are from people who were PCR tested to be positive, the population-wide studies are based on seropositivity and modelling. The Israeli study explicitly calls out that it may be undersampling asymptomatic infections.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#126
post #89

Earlier quoted context omitted.

>once infected the vaccinated spread the virus like unvaccinated You are spreading disinformation. Vaccinated people who do get sick are less likely to spread the virus, and have a high viral load in their system for a shorter duration: --- A vaccinated person may have the same viral loads as an unvaccinated person, but that high level of virus lasts only three to four days compared with an unvaccinated person who co…

>Vaccinated people who do get sick are less likely to spread the virus https://www.medrxiv.org/content/10.1101/2021.07.31.21261387v... "We find no difference in viral loads when comparing unvaccinated individuals to those who have vaccine “breakthrough” infections. " >that high level of virus lasts only three to four days compared with an unvaccinated person who could be contagious for up to 10 days may be. Yet it is…

There are lower rates of viral cell culture positivity in breakthrough infections:

https://www.medrxiv.org/content/10.1101/2021.08.20.21262158v...

Viral mRNA loads also decline faster with breakthrough infections:

https://www.medrxiv.org/content/10.1101/2021.07.28.21261295v...

(also replicated by the recent NBA study that I failed to bookmark, which also found that the Ct levels were similar with delta and prior variants, including old-school D614G although the average for delta was slightly lower but not within the statistical power of the study)

That means that while mRNA loads are similar in breakthrough infections they're composed of more viral debris and they clear faster. That suggests they're less transmissible.

During Alpha, 80% of breakthrough infection is Israel did not transmit in social settings:

https://www.israelnationalnews.com/News/News.aspx/310490

Previously effectiveness against transmission (before delta) was 89% after fully vaccinated:

https://www.israelnationalnews.com/News/News.aspx/297167

There's no evidence that is free from massive confounding factors that delta is really that much of a game changer in vaccinated individuals. Its biggest effects is on pushing the herd immunity threshold across the population near enough to 100% as not to matter and for being twice as bad for unvaccinated individuals.

The reasonable evidence is still that vaccines work and are effective and safe and the best way to end the pandemic, and that delta is still largely transmitting and killing people through the unvaccinated population.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#127
post #9

Does this mean that the ideal path for maximum immunity is to get vaccinated and then get a breakthrough infection?

It sounds like that might be our endgame now. If covid becomes endemic, which may be inevitable, then the only question is whether you want your body to be prepared for its first infection or not. I wonder if this could end up like the 'common cold' coronaviruses, where future generations build up immunity through exposure very early in life, resulting in mild infections in adulthood. That would beg an interesting qu…

The flip side is that delta is very likely optimally transmissible/virulent.

Once immunity is built up to delta, then it'll be forced to evolve to achieve immune escape and that'll make it mutate much more than it has and pick immune escape mutations that will make it "worse" in the immune naive population. Immune escape will come at a cost.

And the scientific evidence of "waning immunity" in the headlines these days is likely wrong and a gigantic lesson in confounding factors. The HCoV-229E common cold coronavirus evolves to escape immunity, and this one probably will as well:

https://journals.plos.org/plospathogens/article?id=10.1371/j...

So our immune systems will evolve and take the edge off of all future coronavirus infections, but the virus will also have to evolve and be forced to make tradeoffs and will become less virulent in the process.

So if you caught one of the common cold coronaviruses right now and had zero inherited immunity to it, then it would probably still be somewhat mild since it would have been evolving for hundreds of years to be more stealthy than virulent. If you caught the original pandemic version though it would probably suck about as hard as SARS-CoV-2 right now.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#128

Earlier quoted context omitted.

We don’t have any long term data on Covid infection either. Why risk children’s lives?

Because the vaccine is a risk factor on its own as well. Do you not agree with that?

The vaccine risk is strictly a subset of the viral risk.

Getting the virus entails getting a lot more of the spike mRNA pumping out a lot more spike protein along with all the rest of the viral machinery and real infectious virions, infecting more cells than just in the muscle of your arm, attacking your heart, lungs, kidneys, etc.

Getting the virus is always going to be worse, for everyone, than getting the vaccine.

Which is also why people refusing to get the vaccine because they've been infected is dumb, because they already beat everything in the vaccine.

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#129
So what is the public policy value of this study? We all should try to get Covid to get immunity to Covid? This is nonsense.

This other study add some value: https://www.cdc.gov/mmwr/volumes/70/wr/mm7032e1.htm

It says that if you already got covid, the possibility of reinfection is 2.4 times lower if you also get the vaccine than if you don't get it. Now I guess that you multiply that natural immunity from 13x to 31x. Isn't cool?

Re: Israeli Study: Natural Immunity Is 13x Stronger Than Pfizer Covid Shots

#130
post #6
post #3

Earlier quoted context omitted.

People should obviously get vaccinated, yes. It does suggest that the vaccines could be improved to be even more effective. It’s also interesting that the people most resistant to delta are people that were both infected and vaccinated.

I seem to recall someone suggested that since a large percentage of the population is vaccinated and are therefore protected against severe covid, we should now actually try to catch it to develop a natural immunity to the virus.

> we should now actually try to catch it to develop a natural immunity to the virus.

We should catch it to get immunity so we don’t catch it ?

I don’t get your thinking here

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